Los Angeles Angels vs. Houston Astros, Picks and Prediction, Saturday, March 28, 2026

By: Bosun Akinpelu Published 03/28/2026, 05:40 AM ET
Angels vs. Astros prediction
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Los Angeles (1-0) will be going for the series win when they visit Daikin Park on Saturday night to face Houston (0-1) in the third game of their four-game series at 7:10 PM. ET. Read on to find out which team picks up the win in this Angels vs. Astros prediction. Don’t go down on strikes! Get our top MLB Betting Picks and increase your bankroll.

Reid Detmers will get the start for the Angels. He was 5-3 with a 3.96 ERA last season. The Astros will counter with Cristian Javier, who was 2-4 with a 4.62 ERA last season.

Houston and Los Angeles split their last 10 meetings.

**This preview was written before Friday’s game was played.**

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Angels Hoping Improved Pitching Ends Playoff Drought

The Angels finished last in the AL West last season and addressed some of their biggest problems by investing in their pitching in the offseason. They picked up a win in their first game and didn’t give up a run in that game. They will be looking for similar results when they play on Saturday.

Los Angele scored three runs in their first game. They finished the game with a .250 batting average, a .372 on base percentage, and a .417 slugging percentage.

Jo Adell led the Angels with a .667 batting average, while Mike Trout had a home run and a RBI.

Los Angeles didn’t give up a score in their first game. They held the Astros to a .100 batting average.

In his last game, Detmers gave up one hit and no runs in 0.1 innings, helping the team get a 4-3 win over Minnesota. He is 1-4 with a 7.83 ERA in 12 games against Houston.

Astros Hoping To Reclaim AL West Title

The Astros have dominated the AL West for close to a decade, winning seven of the last nine AL West titles. They had won the division four years in a row before finishing second to Seattle last year, and will try to reclaim the division this season.

Houston failed to score in the first game of the series. They finished the game with a .100 batting average, a .250 on base percentage, and a .167 slugging percentage.

Joey Loperfido led the Astros with a .600 batting average, while Christian Walker finished the game with a .333 batting average.

Houston gave up three runs in their first game. They will need a better performance from their pitchers if they want to get the win.

In his last start, Javier gave up six hits and four runs in 4.2 innings, leading to a 5-1 loss to the Athletics. He is 5-1 with a 2.93 ERA in 13 games against the Angels.

Angels vs. Astros Picks

Run Line Pick for Angels vs. Astros

  • Houston Astros -1.5 (4 Units)

The Astros have the edge in this game because they hit the ball well against left-handers last season, and they’re going up against Detmers, who has struggled against them, giving up 20 runs in his last three starts against Houston. He gave up 14 runs in his last two road starts against the Astros and will have a hard time slowing them down.

Los Angeles won’t be as successful offensively because they didn’t hit the ball well against right-handers last season, and they’re going up against Javier, who has pitched well against them, giving up eight runs in his last four starts against the Angels. He didn’t give up a run in his last start against the Angels and will keep their offense in check. Take Houston on the run line.

Over/Under Pick for Angels vs. Astros

  • Under (4 Units)

The Angels averaged 4.15 runs per game last season. They had a .224 batting average against right-handers last season, and they’re facing a starter who gave up four runs in his last two starts against them. The Astros averaged 4.23 runs per game last season. They had a .252 batting average against left-handers last season, and they’re facing a starter who gave up 13 runs in his last two starts against them. Don’t expect these teams to score enough runs to push the score over the total.

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