Los Angeles Angels vs Seattle Mariners Picks and Prediction for Saturday, September 26, 2026

By: Dylan Hellebrand Published 09/26/2026, 05:25 AM ET

The Los Angeles Angels (61-98) face off against the Seattle Mariners (74-85) at T-Mobile Park in Seattle, Washington on Saturday. Get involved in the action with our free MLB picks.

Los Angeles vs. Seattle Game Information

  • September 26, 2026
  • 9:40 PM EST
  • T-Mobile Park
  • Angels.TV/MLB.TV/Mariners.TV/Fubo

Seattle Form & Recent Results

The Mariners head into this upcoming matchup trying to find their footing and snap a frustrating one-game losing streak, a recent skid that highlights a larger rough patch where they have dropped three of their last five games leading into Friday. This cold spell has seen them stumble in a few different environments, including a tough road loss against the Rockies up in the high altitude of Denver, a difficult defeat at the hands of the Astros in front of the home crowd, and most recently, a heartbreaking setback right at home against the Angels on Thursday. Despite the disappointing outcome in that 6-4 loss to the Angels, superstar center fielder Julio Rodríguez did everything in his power to spark the lineup, putting together a stellar 2-for-4 performance at the plate that included a sharp single, a towering home run, a run scored, and two RBIs. Beyond Rodríguez's heroics, the rest of the Seattle offense struggled to find their rhythm, finishing the night with just that single long ball and a total of 11 total bases. On the flip side, the pitching staff actually put together a highly aggressive performance in the zone, racking up an impressive 13 strikeouts and pounding the plate for 102 strikes, even though a few costly mistakes ultimately made the difference.

During this season for Seattle, the heavy lifting on offense has consistently been driven by left fielder Randy Arozarena, who continues to anchor the ballclub across multiple major statistical categories. Arozarena is currently pacing the entire Mariners roster as their undisputed power and production source, leading the team with 26 home runs, driving in a team-high 76 RBIs, and setting the tone for consistency with a team-leading .279 batting average. Giving him some serious protection in the lineup is slugging catcher Cal Raleigh, who serves as the roster's second-most lethal deep threat by launching an impressive 23 home runs of his own so far this year. While this potent duo gives Seattle the ability to change any game with a single swing, the team's primary hurdle over the last week has been a suddenly generous defense and pitching staff, which has surrendered an average of 4.8 runs over their last five games. If the Mariners want to turn things around this weekend, they will desperately need to tighten up their run prevention while hoping their marquee bats can ignite a much-needed offensive explosion.

Los Angeles Form & Recent Results

Los Angeles comes into this matchup with a little bit of momentum after picking up a win in their most recent game, though they’ve still been shaky lately. Before Friday, the Angels had lost three of their last five games, with two of those defeats coming against the Athletics in Sacramento and another coming at home against the Twins. They were able to bounce back on Thursday with a 6-4 road victory over the Mariners, a game where their offense did enough to support the pitching staff and hold off Seattle. Second baseman Christian Moore had one of the stronger performances of the night for Los Angeles, going 2-for-4 at the plate with a single, a double, one run scored, and three runs batted in. On the mound, starting pitcher Grayson Rodriguez worked through five innings, giving up five hits and four earned runs while also walking five batters and striking out two. As a team, the Angels finished that game with nine hits and eleven total bases, while their pitching staff allowed seven hits overall and issued five walks.

Get Free $30 Credit for Premium Picks + Exclusive Discounts

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Winners and Whiners may use third-party services to process my data.

Los Angeles has leaned on shortstop Zach Neto as one of its most productive offensive players. Neto currently leads the team in both home runs and RBI, having hit twenty-six long balls while driving in seventy-five runs so far this year. Mike Trout has also been an important power source for the Angels, ranking second on the team with twenty-two home runs, and he leads the club in batting average at .246. While the Angels have shown they can still put together solid offensive performances, their pitching has been a concern recently. Los Angeles has allowed an average of 6.6 runs per game through their last five, which puts a lot of pressure on the lineup to keep pace. If the Angels want to build on their latest win and turn it into a stronger stretch, they will likely need more consistency from both their starting pitchers and bullpen, while continuing to get production from key hitters like Neto, Trout, and Moore.

Key Stats

  • Los Angeles’ Zach Neto this season: 26 HRs, 75 RBI, .238 AVG
  • Seattle’s Randy Arozarena this season: 26 HRs, 76 RBI, .279 AVG

Betting Odds & Market Overview:

  • SEA -191 / LAA +157; O/U 7.5

Los Angeles vs. Seattle Picks and Prediction

The Angels and Mariners have both endured disappointing seasons, and with the season winding down, each team is simply trying to finish on a positive note. Los Angeles will turn to Ryan Johnson, who enters the matchup with a 5-9 record and a 4.93 ERA. Seattle will counter with Kade Anderson, who is 2-2 with a 4.18 ERA on the season. The Angels will be aiming for a repeat performance after beating the Mariners 6-4 on Thursday. Final Score Prediction, Seattle Mariners win 3-2.

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright © 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, Massachusetts, New York, Ontario, or Puerto Rico.