Los Angeles Dodgers vs San Francisco Giants Picks and Prediction for Saturday, September 26, 2026

By: David Anicetti Published 09/26/2026, 05:45 AM ET

The Los Angeles Dodgers and San Francisco Giants meet Saturday at Oracle Park, with the opening pitch scheduled for 4:05 PM ET and the game televised on MLB.TV. Los Angeles is 97-62, first in the NL West with the division clinched, despite dropping its last two games to San Diego. The Dodgers are 7-3 over their last 10 and 46-32 away from home. San Francisco is 65-94, fourth in the NL West and eliminated from playoff contention. The Giants lost 4-2 to Minnesota in their most recent result and are 3-7 over their last 10. Let’s get into the matchup and our free MLB picks.

Los Angeles Dodgers Trying to Respond After Two Losses

Los Angeles has dropped two straight after winning five in a row, including three consecutive victories over San Francisco. The Dodgers beat the Giants 8-2, 10-4 and 3-1 in their previous series. Shohei Ohtani is batting .278 with a .381 on-base percentage and .521 slugging percentage, hitting 30 home runs with 81 RBI. Freddie Freeman leads the club with a .292 average and 167 hits, while Max Muncy has added 29 homers and 76 RBI.

The Dodgers are batting .257 with 790 runs, 199 home runs, a .339 on-base percentage and .425 slugging percentage. Los Angeles ranks near the top of MLB in batting and has also posted a 3.59 ERA, 1.15 WHIP and .219 opponent average, ranking fourth in pitching. The Dodgers have committed 64 errors with a .988 fielding percentage and own a 46-32 road record.

Injuries: Gavin Stone (out), Jake Cousins (out), Ben Casparius (out), Brusdar Graterol (out), Dalton Rushing (out).

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San Francisco Giants Trying to Stop Another Losing Stretch

San Francisco has lost four of its last five, with the lone victory coming 5-2 against Minnesota. The Giants have scored only 12 runs during that five-game stretch. Rafael Devers has been the main power source, batting .258 with 37 home runs, 98 RBI and a .525 slugging percentage. Jung Hoo Lee leads San Francisco with a .276 average and 149 hits, while Casey Schmitt has 21 home runs and 55 RBI.

The Giants are batting .246 with 665 runs, 178 home runs, a .308 on-base percentage and .403 slugging percentage. San Francisco ranks 13th in MLB batting but 23rd in pitching with a 4.36 ERA, 1.36 WHIP and .248 opponent average. The Giants are 37-41 at Oracle Park. San Francisco has committed 106 errors with a .982 fielding percentage, tied for the lowest fielding mark in MLB.

Injuries: Bo Davidson (questionable), Osleivis Basabe (questionable), Willy Adames (out), JT Brubaker (out), Matt Gage (out).

Pitching Matchup

Los Angeles Dodgers - Blake Snell

Blake Snell is 4-1 with a 1.86 ERA and 1.09 WHIP across 38.2 innings. He has allowed 26 hits and no home runs while recording 52 strikeouts and 16 walks.

San Francisco Giants - Matt Wilkinson

Matt Wilkinson is 1-3 with a 3.65 ERA and 1.01 WHIP across 24.2 innings. He has allowed 21 hits and four home runs while recording 18 strikeouts and four walks.

Los Angeles Dodgers vs San Francisco Giants Game Pick

  • Los Angeles Dodgers

The Dodgers are the pick behind Snell and the large gap between these clubs across the season. Snell has a 1.86 ERA with 52 strikeouts in 38.2 innings and has yet to allow a home run. Los Angeles also owns a .339 on-base percentage and has scored 790 runs, compared with San Francisco’s .308 on-base percentage and 665 runs. The Dodgers have already won six of the first 10 meetings in the season series, including the last three, and their pitching staff has a 3.59 ERA.

Los Angeles Dodgers vs San Francisco Giants Over/Under Pick

  • under

Under is the pick with Snell allowing only 26 hits and zero home runs through 38.2 innings. San Francisco has scored two runs or fewer in four of its last five games, including three losses to Los Angeles during that span. Wilkinson has a 3.65 ERA and 1.01 WHIP through 24.2 innings, while the Dodgers have scored just three runs across their last two games. The recent scoring from these clubs and the starting pitching matchup make a lower-scoring result likely.

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