Miami Marlins vs. Philadelphia Phillies, Picks and Prediction, Wednesday, September 24, 2025

By: Bosun Akinpelu Published 09/24/2025, 03:26 AM ET
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Miami (76-80) will be trying to pick up their third consecutive road series win when they visit Citizens Bank Park on Wednesday night to face Philadelphia (92-64) in the second game of their three-game series at 6:45 PM. ET. Read on to find out which team picks up the win in this Marlins vs. Phillies prediction. Need a hot take on the MLB Season? Check out our Free MLB Picks and cash in.

Ryan Weathers, 2-1, 3.21 ERA, will get the start for the Marlins. The Phillies will counter with Jesus Luzardo, 14-7, 4.08 ERA.

Philadelphia is 7-3 in its last 10 games against Miami.

**This preview was written before Tuesday’s game was played.**

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Miami Trying To Stay Hot

The Marlins have been on a roll over the past couple of weeks, and they’ve won 10 of their last 11 games. They will try to keep the momentum going and pick up their fourth straight series win when they play the Phillies.

Miami averages 4.44 runs per game, which is 16th in the league. Their .252 batting average is seventh in the league. Their .316 on-base percentage is 16th, while their .397 slugging percentage is 18th.

Kyle Stowers leads Miami with a .288 batting average and 25 home runs, while Otto Lopez leads the team with 77 RBI.

Miami is giving up 4.96 runs per game, which is 26th in the league. Opponents have a .249 batting average against the Marlins, which is 22nd in the league. Their 4.63 ERA is 25th, while their 1.30 WHIP is 19th.

In his last start, Weathers gave up eight hits and three runs in four innings, leading to an 8-4 win over Colorado. He is 0-2 with a 9.45 ERA in two games against Philadelphia.

Philadelphia Still In Race For NL Lead

The Phillies followed up their series win over the Dodgers with a series loss to the Diamondbacks. They’ve already clinched the NL East title, but they’re three games behind the Brewers, who have the best record in the National League. They will try to turn things around and cut into Milwaukee’s lead when they play on Wednesday.

Philadelphia averages 4.85 runs per game, which is seventh in the league. Their .260 batting average is third in the league. Their .330 on-base percentage is fourth, while their .431 slugging percentage is fifth.

Trea Turner leads the Phillies with a .305 batting average, while Kyle Schwarber leads the team with 53 home runs and 129 RBI.

Philadelphia is giving up 4.06 runs per game, which is sixth in the league. Opponents have a .246 batting average against the Phillies, which is 18th in the league. Their 3.88 ERA is 12th, while their 1.25 WHIP is 10th.

In his last start, Luzardo gave up six hits and four runs in seven innings, leading to a 5-0 loss to the Dodgers. He is 1-1 with a 3.50 ERA in three games against Miami.

Marlins vs. Phillies Pick

Money Line Pick for Marlins vs. Phillies

  • Philadelphia Phillies ML (4 Units)

The Phillies have won six of their last seven home games, while the Marlins have won six of their last seven road games. Philadelphia has the edge here because they’ve had a lot of success against left-handers, and they’re going up against Weathers, who has struggled on the road, giving up nine runs in his last three road starts. He gave up seven runs in two starts against the Phillies and will have a hard time slowing them down.

Miami won't be as successful offensively because they haven’t hit the ball well against left-handers, and they’re going up against Luzardo, who has done well on the mound, especially at home, where he gave up five runs in his last three starts, so expect him to keep Miami’s offense in check. Take Philadelphia on the money line.

Over/Under Pick for Marlins vs. Phillies

  • Under (4 Units)

The Marlins played under the total in their last two games, while the Phillies played under the total in two of their last four games. Miami averages 4.44 runs per game and averaged 4.67 runs per game in their last three games. They’re batting .235 against left-handers, and they’re facing a starter who gave up eight runs in three starts against them. The Phillies average 4.85 runs per game and averaged 4.33 runs per game in their last three games. They’re batting .252 against left-handers, and they’re facing a starter who gave up seven runs in his last three starts. Don't expect these teams to score enough runs to push the score over the total. The Marlins and Phillies played under the total in three of their last five meetings.

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