Milwaukee Brewers vs Cincinnati Reds Picks, Prediction, Odds, and Line Movement for Monday June 22 2026

By: Al MacMillan Published 06/22/2026, 01:51 PM ET
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Milwaukee visits Cincinnati with updated picks, pitching analysis, and top MLB player props for Monday night.

Best Available Odds

Best Moneyline Odds: Milwaukee Brewers (-148 at FanDuel) / Cincinnati Reds (+130 at DraftKings)

Best Spread Odds: Milwaukee Brewers -1.5 (+105 at FanDuel) / Cincinnati Reds +1.5 (-123 at DraftKings)

Best Total Odds: Over 9.5 (-104 at DraftKings) / Under 9.5 (-102 at BetMGM)

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Game Info

Date: June 22, 2026

Time: 7:10 PM EDT

Location: Great American Ball Park, Cincinnati, OH

TV: Brewers.TV, Reds.TV

Milwaukee Brewers vs Cincinnati Reds Preview

The Milwaukee Brewers enter Monday at 46-29 and remain in first place in the NL Central. Milwaukee avoided a sweep in Atlanta with a 9-4 victory Sunday, scoring eight runs during the second inning and ending a three-game losing streak.

William Contreras led the offensive breakout by going 4-for-5 with a three-run home run. Jackson Chourio, Brice Turang, Jake Bauers, Andrew Vaughn, Christian Yelich, Garrett Mitchell, and Sal Frelick give Milwaukee one of the National League's deepest and most balanced lineups.

The Brewers have scored 397 runs through 75 games, an average of approximately 5.29 per contest. They rank third in the majors in runs while batting .256 with a .340 on-base percentage and .394 slugging percentage.

Milwaukee does not depend entirely on home runs. The Brewers have hit only 68, but they combine strong on-base production with 75 stolen bases, productive contact, and the ability to score from multiple points in the order.

Chourio enters batting .301 with 10 home runs, while Contreras is hitting .299 after his four-hit performance Sunday. Bauers leads the team with 13 home runs, and Turang has added 11 homers with a team-high 49 walks.

The Brewers have also been one of baseball's strongest pitching teams. Milwaukee owns a 3.45 staff ERA, including a 3.37 mark from its starters and a 3.55 bullpen ERA.

Aaron Ashby, Abner Uribe, Trevor Megill, Grant Anderson, and Chad Patrick give Milwaukee several reliable relief options. That bullpen depth becomes especially important with Brandon Woodruff returning from a lengthy absence.

Milwaukee remains without pitchers Logan Henderson, Jared Koenig, Quinn Priester, DL Hall, Coleman Crow, and several depth arms. Outfielder Brandon Lockridge is also on the injured list.

The Cincinnati Reds enter at 37-39 after winning four of their last five games. Cincinnati took two of three from both the New York Mets and New York Yankees during a productive 4-2 week.

The Reds closed their weekend series with consecutive road victories over the Yankees. They won 10-2 on Saturday before Chase Burns led them to a 4-1 victory Sunday, with Tyler Stephenson delivering a three-run home run.

Cincinnati has scored 325 runs while batting .229 with a .311 on-base percentage and .395 slugging percentage. The Reds have hit 96 home runs but have struggled to consistently place runners on base around those power swings.

Sal Stewart leads Cincinnati with 14 home runs, while JJ Bleday has 13. Spencer Steer and Elly De La Cruz have each hit 12, although De La Cruz remains unavailable for Monday's series opener.

De La Cruz is completing a Triple-A rehabilitation assignment after suffering a right hamstring strain. He is scheduled to return Tuesday, leaving Cincinnati without its most dynamic combination of power, speed, and defense for one more game.

Ke'Bryan Hayes is also unavailable, while Hunter Greene, Emilio Pagรกn, Brandon Williamson, and Graham Ashcraft remain sidelined from the pitching staff.

The Reds carry a 4.58 team ERA, including a 4.43 rotation ERA and a 4.81 bullpen mark. Brock Burke, Sam Moll, Tejay Antone, and Caleb Ferguson have supplied some dependable relief work, but the staff has lacked consistent depth throughout the season.

Cincinnati is only 2-13 against NL Central opponents. The Reds' recent improvement is meaningful, but they now face the division's strongest team and a starter with an established record of success against them.

Starting Pitchers and Pitching Matchup

The Brewers will start right-hander Brandon Woodruff, who returns from the injured list with a 2-1 record, 3.60 ERA, 1.03 WHIP, and 25 strikeouts across 30 innings.

Woodruff has not appeared in the majors since April 30. His fastball velocity declined during that outing, and Milwaukee later placed him on the injured list with right shoulder inflammation.

The Brewers found no new structural damage in the shoulder, allowing Woodruff to progress through a throwing program and two rehabilitation starts. He completed nine total rehab innings, allowing six runs on 10 hits and three walks while striking out 11.

Woodruff reached 82 pitches across 5.2 innings in his final rehabilitation appearance. That workload should allow him to operate under a normal starting assignment rather than functioning as a short opener.

Before the injury, Woodruff had limited opponents to 24 hits and seven walks. His 3.97 FIP was slightly higher than his ERA but still reflected dependable run prevention and command.

Woodruff's strikeout production was below his career peak during the first six starts, but his rehab results showed improving swing-and-miss ability. He recorded 11 strikeouts in nine innings while building his workload.

The veteran also owns extensive success against Cincinnati. Woodruff is 7-4 with a 3.48 ERA and 106 strikeouts across 75 career innings against the Reds.

Cincinnati's current lineup is missing De La Cruz and has produced a .227 batting average and .307 on-base percentage against right-handed pitching. The Reds still offer legitimate power, but Woodruff's command should prevent them from receiving many free baserunners.

The Reds counter with right-hander Brady Singer, who enters at 3-6 with a 5.32 ERA, 1.61 WHIP, and 52 strikeouts across 66 innings.

Singer has allowed 83 hits, 39 earned runs, 23 walks, and 17 home runs. His 6.15 FIP indicates that the underlying performance has been even less effective than his already elevated ERA.

His sinker remains his most frequently used pitch, but opponents have hit .314 and slugged .538 against it. Singer's sweeper has also been vulnerable, allowing a slugging percentage above .700.

Singer has improved during his last several outings. He has allowed four earned runs across his last 15 innings and only three runs over his last two starts against the Mets and Padres.

He earned his first victory since April 25 during his latest appearance, continuing a stretch in which he has reduced the number of damaging innings. The recent improvement makes him more competitive than his season ERA alone suggests.

Singer has still struggled to provide length. He has recorded more than 15 outs only once in his last six starts, frequently requiring Cincinnati's bullpen to cover four or more innings.

Milwaukee presents a difficult matchup because the Brewers combine patient left-handed hitters with several productive right-handed bats. Yelich, Turang, Bauers, Mitchell, and Frelick can pressure Singer from the left side, while Chourio and Contreras supply additional contact and power.

Singer has made four career starts against Milwaukee, producing a 2-2 record and 4.82 ERA across 18.2 innings. He failed to complete more than five innings in any of his three meetings with the Brewers last season.

Game Thesis: Milwaukee owns advantages in lineup depth, starting-pitcher quality, bullpen performance, and season-long consistency. Woodruff's return introduces some uncertainty, but his final rehabilitation workload suggests he is prepared for a normal start. Singer has pitched better recently, which makes the Under more attractive than assuming another immediate offensive explosion. The Brewers should generate enough traffic against Singer to win without requiring a double-digit game.

โญ Best Bet - Moneyline Pick: Milwaukee Brewers (-148)

The Brewers moneyline is the strongest game wager. Milwaukee owns the better record, stronger lineup, superior pitching staff, and a substantial advantage in bullpen performance.

Woodruff provides a higher ceiling and stronger command profile than Singer. Even after missing nearly two months, the veteran returns with a 1.03 WHIP and a lengthy record of success against Cincinnati.

The Reds enter in improved form, but their recent victories do not erase their 2-13 record against NL Central opponents. Cincinnati is also playing Monday without De La Cruz, weakening both the lineup and infield defense.

Milwaukee has several ways to attack Singer. The Brewers can use their left-handed hitters against his vulnerable sinker, create traffic through walks and singles, and force Cincinnati into its bullpen before the late innings.

The Brewers bullpen provides another decisive advantage. If Woodruff completes five or six competitive innings, Milwaukee can use Ashby, Uribe, Megill, and its remaining high-leverage arms to protect a narrow lead.

The run line offers more upside, but Woodruff's return and Singer's improved recent performance make the straight moneyline the more dependable position.

Spread Pick: Milwaukee Brewers -1.5 (+105)

Milwaukee -1.5 is the higher-return extension of the moneyline pick. Singer's 1.61 WHIP and inability to consistently pitch beyond the fifth inning give the Brewers several opportunities to build separation.

Milwaukee has scored the third-most runs in baseball despite ranking near the bottom in home runs. The Brewers can create multi-run innings through contact, walks, stolen bases, and productive hitting rather than depending on one swing.

Great American Ball Park also increases the potential for Milwaukee's left-handed hitters to generate extra-base damage. Yelich, Bauers, Turang, Mitchell, and Frelick should all receive favourable opportunities against Singer and Cincinnati's relief staff.

The primary risk is Woodruff's first major-league outing in nearly two months. A shorter start would increase Milwaukee's bullpen workload and give Cincinnati additional chances against the middle-relief group.

Singer's recent improvement also makes an immediate blowout less certain. The Brewers run line is playable at plus money, but the moneyline remains the stronger overall wager.

Total Pick: Under 9.5 (-102)

The Under 9.5 is the preferred total. Singer's full-season numbers are poor, but he has allowed only three runs across his last 11 innings and four over his last 15.

Woodruff should also provide Cincinnati with a more difficult matchup than the average returning starter. He reached 82 pitches in his final rehab appearance and has historically controlled the Reds through strikeouts and limited baserunners.

Cincinnati will play without De La Cruz, removing 12 home runs, 37 RBIs, 10 stolen bases, and one of the lineup's strongest on-base threats.

The Brewers bullpen owns a 3.55 ERA and should be prepared to cover the later innings if Woodruff exits after five or six. Cincinnati has also received improved relief work from Burke, Moll, Antone, and Ferguson.

Great American Ball Park creates clear home-run risk, while Singer has allowed 17 long balls. Milwaukee could threaten the total through a large individual scoring performance.

However, a final in the range of 5-3, 6-3, or 5-2 would give the Brewers a comfortable victory while remaining below 9.5. Singer's recent form and Woodruff's return make the Under more appealing than the original Over recommendation.

Top Player Prop Picks

Christian Yelich Over 1.5 Hits (+190 at BetMGM) Yelich enters batting .269 and has improved to approximately .282 during June. He should hit near the top of Milwaukee's order and receive four or five plate appearances against Singer and the Cincinnati bullpen.

Singer has allowed 83 hits in 66 innings and carries a 1.61 WHIP. His sinker has been hit particularly hard, creating a favourable matchup for Yelich's ability to drive low pitches through the middle and opposite side of the field.

Yelich should also benefit from Great American Ball Park's compact dimensions. Line drives into the gaps and balls pulled toward right field have a greater opportunity to become extra-base hits.

The two-hit requirement creates more risk than a standard one-hit wager, but the +190 price compensates for that higher threshold. Yelich's lineup position and Singer's contact profile give him enough opportunities to record multiple hits.

Brandon Woodruff Over 5.5 Strikeouts (+120) Woodruff recorded 25 strikeouts across 30 innings before the shoulder injury and added 11 more during nine rehabilitation innings.

He reached 82 pitches in his final rehab start, giving him enough projected workload to pursue six strikeouts. Woodruff does not need to complete seven innings if his fastball and breaking pitches generate early swings and misses.

The veteran has recorded 106 strikeouts across 75 career innings against Cincinnati. His familiarity with the Reds and ability to command several pitches give him a strong matchup against a lineup missing De La Cruz.

Cincinnati has also struck out 597 times through 76 games. Woodruff should have opportunities throughout the order, particularly against the Reds' lower-contact power hitters.

The return from the injured list introduces workload risk, but plus-money odds make the Over attractive for a pitcher who has historically produced more than one strikeout per inning against Cincinnati.

Brady Singer Under 15.5 Pitcher Outs (-143) Singer has stayed below 15.5 outs in five of his last six starts. He has completed more than five innings only once during that stretch.

Milwaukee's patient lineup can extend at-bats and increase Singer's pitch count. The Brewers rank among the league leaders in walks and on-base percentage, forcing pitchers to work through traffic even when they avoid major damage.

Singer has also failed to record more than 15 outs in each of his last three starts against Milwaukee. The Brewers' left-handed hitters create difficult matchups against his sinker and sweeper.

Cincinnati may allow Singer to work through five innings if he remains effective, but he must record at least one out in the sixth to defeat this Under. His recent usage and the matchup both support an exit after five innings or fewer.

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