Milwaukee Brewers vs Los Angeles Angels Picks and Prediction for Thursday, September 18, 2025

By: Kevin V. Published 09/18/2025, 10:27 AM ET
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The Los Angeles Angels (69-82, 5th AL West) play the final game of a three-game series on the road Thursday versus the Milwaukee Brewers (92-59, 1st NL Central). Los Angeles lost to Milwaukee 9-2 in the first game of the series on Tuesday. Los Angeles has lost five straight and has been eliminated from postseason contention. Milwaukee has won three of the last four and leads the National League Central by five games. The Brewers have clinched a postseason berth, and Milwaukee's magic number has been reduced to seven to clinch the NL Central title. Los Angeles will play without eight pitchers as well as position players Gustavo Campero, Jorge Soler, Travis d’Arnaud, and Zach Neto. Milwaukee will play without 10 pitchers as well as position players Ramon Rodriguez and Garrett Mitchell. Make sure to read this in-depth Los Angeles Angels vs Milwaukee Brewers prediction. Chasing wins? Get the edge with our MLB picks for the Los Angeles Angels at the Milwaukee Brewers prediction right now.

This article was written before these two played on Wednesday.

Los Angeles performs poorly at the plate and on the mound

The Los Angeles Angels have been eliminated from postseason contention, which is not a big surprise, as they have performed poorly at the plate. Los Angeles is 17th in slugging percentage, 23rd in runs scored, 28th in on-base percentage, and 29th in batting average. Jo Adell has 36 home runs to lead Los Angeles. The most productive hitter for the Angels has been Taylor Ward, who leads Los Angeles in doubles with 31, leads in RBI with 98, and is second in home runs with 31. Los Angeles has hit 202 doubles, 17 triples, and 209 home runs for 428 extra base hits in 151 games.

Los Angeles is performing poorly on the mound, as the Angels are 20th in Quality Starts, 28th in both ERA and batting average against, while 29th in WHIP. Jose Soriano leads Los Angeles in wins with 10. On Thursday, Los Angeles will hand the ball to Yusei Kikuchi. This season, the left-hander is 6-11 with a 4.08 ERA, 1.46 WHIP, and 166 strikeouts. Kikuchi leads Los Angeles in strikeouts and ERA for starters.

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Milwaukee is on the verge of clinching the NL Central

The Milwaukee Brewers have won 92 of 151 games thus far this season and have a magic number of seven to clinch the National League Central title. Milwaukee has performed well at the plate as the Brewers are second in both batting average and on-base percentage, while third in runs scored and 12th in slugging percentage. Milwaukee's most productive hitter has been Christian Yelich, who leads the Brewers in both home runs with 29 and RBI with 99. Brice Turang is the leader in hits with 157. Milwaukee has 247 doubles, 16 triples, and 161 home runs for 424 extra base hits in 151 games.

While Milwaukee has struggled in Quality Starts, sitting at 24th, the Brewers are 2nd in ERA, 3rd in batting average against, and 7th in WHIP. The Brewers are led on the mound by starting pitcher Freddy Peralta, who leads the Brewers in wins with 17, strikeouts with 195, and ERA for starters, with 2.65. Quinn Priester gets the nod on the mound Thursday for Milwaukee. This season, the right-hander is 13-2 with a 3.25 ERA, 1.23 WHIP, and 118 strikeouts.

Milwaukee Brewers vs. Los Angeles Angels Pick

Spread Pick for Milwaukee Brewers vs. Los Angeles Angels

  •  Milwaukee Brewers -1.5 (4 units)

Los Angeles has lost five straight overall, and the Angels have dropped six straight on the road. Milwaukee has won four of its last six, and the Brewers have won five of the last seven head-to-head versus Los Angeles. Milwaukee is second in team ERA, while Los Angeles is second from the bottom at 28th. The Brewers are 3rd in runs scored, and Los Angeles is 23rd. Los Angeles starting pitcher Yusei Kikuchi has had three poor outings in his last four appearances. In the three below-average starts, the left-hander gave up 18 hits and 18 runs in only 11.2 innings. Milwaukee starter Quinn Priester has performed well in each of his last five outings, allowing 25 hits but just seven runs in 28.0 innings pitched, resulting in Milwaukee winning each of the five games.

Over/Under Pick for Milwaukee Brewers vs. Los Angeles Angels

  • Over (4 units)

The total has finished over in five of Milwaukee's last six games, in five of Milwaukee's last seven games against Los Angeles, and in four of Milwaukee's last five games against the team from the American League. Los Angeles has had the total finish over in four of its last five games. Milwaukee is third in runs scored, second in batting average, and second in on-base percentage. The total has finished over in three of LA starter Yusei Kikuchi’s last four outings. The total was over in the opening game of this series with 11 runs scored.

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