Minnesota Twins vs Los Angeles Angels Picks and Predictions for Sunday, September 20th, 2026

The Minnesota Twins will finish their 3-game road series Sunday afternoon with a 4:07 PM matchup against the Los Angeles Angels at Angel Stadium, and we have you ready to go with our Minnesota vs. Los Angeles prediction. Minnesota enters Sunday 11 games below .500 and near the bottom of the American League Central standings. Los Angeles is 35 games below .500 and occupies last place in the American League West. The Angels secured a dramatic extra-inning victory Saturday, while the Twins will attempt to recover after allowing a 3-run lead to disappear during the final 4 innings.. Read more about this Minnesota vs. Los Angeles prediction! Struggling with handicapping? Try our MLB Predictions! 

Twins try to recover

Minnesota has a .244 team batting average this season, scoring 699 runs on 1,265 hits. The Twins have recorded a .317 on-base percentage and a .403 team slugging percentage. Minnesota’s pitching staff has struggled throughout the year, entering Sunday with a 4.64 team ERA after allowing 770 runs. Luke Keaschall leads the Twins with a .278 batting average and 140 hits. Kody Clemens has hit a team-high 26 home runs, while Josh Bell leads Minnesota with 89 RBIs.Joe Ryan started for Minnesota on Saturday, allowing 2 runs on 7 hits through 5 innings. Ryan struck out 5 batters, walked 1, and gave the Twins a chance to build an early lead. Andrew Morris and Jeff Hoffman followed with 2 scoreless innings before the rest of the Minnesota bullpen struggled. Yoendrys Gomez gave up 2 runs in the 8th inning, and A.J. Minter surrendered the game-tying home run in the 9th. Taylor Rogers took the loss after allowing 1 unearned run on 1 hit and 2 walks over 1.2 innings.

The Twins finished Saturday’s loss with 11 hits but went scoreless over the final 3 innings. Victor Caratini led Minnesota with 2 hits and 2 RBIs. Josh Bell, Royce Lewis, and Walker Jenkins also finished with 2 hits each. Ryan Kreidler supplied the Twins’ only home run and drove in 1 run. Luke Keaschall added 1 hit, 1 RBI, and 1 run scored as Minnesota built a 5-2 advantage before the Angels completed their comeback. Dean Kremer will start for Minnesota in Sunday’s matchup. Kremer enters with a 3-5 record, a 5.35 ERA, and a 1.24 WHIP through 77.1 innings. The right-hander has recorded 74 strikeouts while allowing 70 hits, 26 walks, and 17 home runs. Kremer has struggled to keep the ball inside the park, which could become an issue against an Angels lineup that hit 3 home runs Saturday.

Key Injury Report for Minnesota:

• Trevor Larnach LF 10-Day IL
• Kaelen Culpepper SS 10-Day IL
• Byron Buxton CF 10-Day IL
• Cole Sands RP 60-Day IL
• David Festa SP 60-Day IL

Angels look to build momentum

The Los Angeles offense has struggled this season, posting a .233 batting average with 619 runs scored on 1,198 hits. The Angels have recorded a .308 on-base percentage and a .369 team slugging percentage. Los Angeles has been more respectable on the mound, carrying a 4.19 team ERA after allowing 699 runs. Zach Neto leads the Angels with a .239 batting average, 26 home runs, 74 RBIs, and 142 hits. Mike Trout owns a team-high .380 on-base percentage.Reid Detmers started for Los Angeles on Saturday, giving up 4 runs on 6 hits through 5 innings. Detmers struck out 5 batters without issuing a walk before turning the game over to the bullpen. The Angels’ relief pitchers were fantastic, allowing just 1 run on 5 hits across the final 6 innings. Ryan Watson gave up the only run charged to the bullpen, while Mitch Farris, Ben Joyce, and Tayler Saucedo combined for 3 perfect innings. Saucedo earned the win after striking out 2 batters in the top of the 11th.

Jose Siri helped start the Los Angeles comeback with a 2-run home run in the 4th inning. Adam Frazier delivered a 2-run double during the 8th, cutting Minnesota’s lead to 1 run. Vaughn Grissom then tied the game with a solo home run in the bottom of the 9th inning. After both teams went scoreless in the 10th, Christian Moore delivered a walk-off infield single with the bases loaded and 1 out in the bottom of the 11th. Mike Trout and Siri led the Angels with 2 hits each.Ryan Johnson will take the mound for Los Angeles on Sunday. Johnson is 5-8 with a 4.88 ERA and a 1.34 WHIP through 90.1 innings this season. He has struck out 70 batters while surrendering 82 hits, 39 walks, and 18 home runs. Johnson has also experienced problems with the long ball, creating scoring opportunities for a Minnesota lineup that owns a respectable .403 slugging percentage.

Key Injury Report for Los Angeles:

• George Klassen SP 15-Day IL
• Nolan Schanuel 1B 10-Day IL
• Yoan Moncada 3B 60-Day IL
• Gustavo Campero OF 10-Day IL
• Jack Kochanowicz SP 60-Day IL

Minnesota vs. Los Angeles Pick

• Minnesota vs. Los Angeles Spread Pick

Minnesota let Saturday’s game slip away, but the Twins remain the better offensive team in this matchup. Minnesota has scored 80 more runs than Los Angeles this season and holds advantages in batting average, on-base percentage, and slugging percentage. The Twins produced 11 hits Saturday and should have more scoring opportunities against Johnson, who carries a 4.88 ERA.Kremer has not pitched well enough to trust Minnesota to shut down the Angels completely. However, Los Angeles needed a late rally and 11 innings to secure Saturday’s victory. The Angels also used 6 relief pitchers, while Minnesota should be motivated to respond after blowing a 3-run lead. Look for the Twins to take advantage of Johnson and generate enough offense to secure the road victory.

• Minnesota vs. Los Angeles Over/Under Pick

Both teams will send vulnerable starting pitchers to the mound Sunday. Kremer carries a 5.35 ERA and has allowed 17 home runs in 77.1 innings. Johnson owns a 4.88 ERA and has surrendered 18 home runs through 90.1 innings. Neither starter has consistently worked deep into games without allowing damage.Minnesota scored 5 runs Saturday, while Los Angeles responded with 6. Both offenses produced 11 hits and combined for 3 home runs. The extended game also forced both teams to use several relief pitchers, potentially leaving each bullpen in a difficult position Sunday. Expect both lineups to produce early before adding more runs against tired relief units.

Final Score Prediction: Minnesota Twins win 7-5