Minnesota Twins vs New York Mets Picks, Prediction, Odds, and Line Movement for Wednesday April 22 2026
Use Code WWWC The Minnesota Twins vs New York Mets matchup on April 22, 2026 presents one of the more intriguing MLB picks on the board, as bettors must weigh a proven starter against an untested arm while navigating recent form that heavily favors Minnesota. For those searching for sharp MLB predictions, this game offers value opportunities on both the spread and total, especially given the Mets’ prolonged struggles and the Twins’ stronger offensive profile.
Quick Picks and Prediction
- Spread: Twins +1.5
- Total: Under 8
- Projected Score: Mets 4, Twins 3
Odds and Line Movement
Opening Odds
| Team | Moneyline |
|---|---|
| MIN | +135 |
| NYM | -163 |
Current Odds
| Team | Moneyline |
|---|---|
| MIN | +135 |
| NYM | -163 |
Line Movement - Run Line
| Date | Time | Minnesota | NY Mets | Public ($, #) |
|---|---|---|---|---|
| 04/22 | 08:33:42AM | +135 | -163 | NYM 59%, MIN 71% |
| 04/22 | 07:36:57AM | +129 | -156 | NYM 63%, MIN 69% |
| 04/22 | 03:02:35AM | +135 | -163 | NYM 66%, MIN 85% |
| 04/22 | 01:45:21AM | +129 | -156 | NYM 66%, MIN 85% |
| 04/21 | 09:24:04PM | +135 | -163 | - |
Line Movement - Total
| Date | Time | Over | Under | Public ($, #) |
|---|---|---|---|---|
| 04/22 | 10:12:42AM | 7.5 -118 | 7.5 -102 | Under 100%, Under 100% |
| 04/22 | 10:10:43AM | 8 -102 | 8 -118 | Under 100%, Under 100% |
| 04/22 | 10:09:58AM | 8 -105 | 8 -115 | Under 100%, Under 100% |
| 04/22 | 09:25:42AM | 8 -112 | 8 -108 | Under 100%, Under 100% |
| 04/22 | 08:50:12AM | 8 -115 | 8 -105 | Under 100%, Under 100% |
Minnesota Twins
Minnesota enters this matchup in a favorable offensive position, producing 117 runs with 27 home runs and a .329 OBP, clearly outpacing New York’s overall output. Byron Buxton continues to supply power while Josh Bell leads the team with 15 RBI, giving the Twins multiple avenues to generate scoring. Even with uncertainty surrounding Connor Prielipp’s role, Minnesota’s lineup depth keeps them competitive in any game script.
New York Mets
The Mets rely heavily on Clay Holmes, who has delivered strong results with a 1.96 ERA and 1.09 WHIP across 23 innings. However, the offense has lagged significantly, producing just 75 runs with a .285 OBP and .332 slugging percentage. Francisco Alvarez remains the most consistent threat with 4 home runs and a .357 OBP, but overall run production has been inconsistent, especially during their recent slide.
Twins vs Mets Key Matchups and Handicap
The central handicap revolves around Holmes’ stability versus Prielipp’s uncertainty. Holmes provides a strong floor, limiting baserunners and keeping games within reach, but Minnesota’s superior offensive numbers and recent win in the series opener highlight their ability to create scoring chances. The Mets’ extended losing streak adds pressure, and without consistent offensive support, even a strong outing from Holmes may not be enough to create separation.
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Betting Trends MIN and NYM
- Twins have the stronger offensive production metrics overall
- Mets are currently on a 12-game losing streak
- Minnesota won the previous matchup 5-3
- Total has seen heavy action on the Under
Key Injuries and Notes MIN and NYM
- Twins missing multiple bullpen arms including Cody Laweryson and Julian Merryweather
- Kody Funderburk unavailable due to paternity leave
- Mets without Juan Soto and Jorge Polanco
- Additional bullpen absences for NYM include Nate Lavender, Joey Gerber, and A.J. Minter
Twins vs Mets ATS and Total Picks
- Twins +1.5 offers the best spread value due to offensive edge
- Under 8 remains the strongest total lean with heavy market support
Final Score Prediction
Mets 4, Twins 3
How to Bet
This game is best approached by focusing on the run line and total rather than chasing the moneyline. Bettors can explore options through social sportsbooks for flexible wagering, while those seeking promotions can take advantage of offers like the bet365 bonus code or the fliff promo code. Given the matchup dynamics, backing Minnesota on the spread while targeting the Under provides the most balanced risk-reward profile.
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