Minnesota Twins vs Philadelphia Phillies Picks and Prediction for Sunday, September 28, 2025
Use Code WWWC On Sunday, the Minnesota Twins (69-91, 4th AL Central) visit Citizens Bank Park in Philadelphia to play the Philadelphia Phillies (95-65, 1st NL East) in the final game of the 2025 MLB regular season for both teams. Minnesota lost to Philadelphia 3-1 on Friday in the opening game of the series. Minnesota has lost two of the last three and seven of the last 10. The Twins have been eliminated from postseason contention. Philadelphia has won three straight following its victory on Friday. The Phillies have clinched the National League East title and are battling Milwaukee for the best record in the NL. Minnesota will play without five pitchers as well as position players Luke Keaschall, Matt Wallner, and Allan Roden. Philadelphia will play without four pitchers as well as position players Carson Taylor and Marcus Lee Sang. Make sure to read this in-depth Minnesota Twins vs Philadelphia Phillies prediction. From first pitch to final inning, our MLB picks for the Minnesota Twins at Philadelphia Phillies prediction keep you covered.
This article was written before these two played on Saturday
Minnesota performs poorly at the plate and on the mound
The Minnesota Twins are 16th in slugging percentage, 21st in on-base percentage. 22nd batting average, and 24th in runs scored. Byron Buxton has been Minnesota's most productive hitter all season, leading the Twins in batting (.263), home runs (34), RBI (82), hits (127), and on-base percentage (.326). Matt Wallner is a distant second in home runs with 22, but is out injured. Brooks Lee is second in RBI with 64. Minnesota has hit 245 doubles, 20 triples, and 188 home runs for 453 extra-base hits in 160 games.
On the mound, Minnesota is 22nd in WHIP, 25th in both ERA and batting average against, and 26th in Quality Starts. Joe Ryan leads Minnesota in wins with 13, strikeouts with 194, and ERA, for starters with 3.47. Simeon Woods Richardson will get the nod on the mound Sunday. This season, the right-hander is 7-4 with a 4.27 ERA, 1.34 WHIP, and 98 strikeouts.
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Philadelphia is tough at the plate and only slightly less effective on the mound
The Philadelphia Phillies are in the top eight of four hitting categories. Philadelphia is second in batting average, third in slugging percentage, fourth in on-base percentage, and 8th in runs scored. Kyle Schwarber has been Philadelphia's power supply with 56 home runs and 132 RBI, leading Philadelphia in both categories. Bryce Harper is second in both home runs with 27 and RBI with 75. Philadelphia has eight players with 51 or more RBI. The Phillies have hit 260 doubles, 24 triples, and 211 home runs for 503 extra base hits in 160 games
Philadelphia is in the top 10 of three pitching categories and 17th in another. Philadelphia's first in Quality Starts, 8th in ERA, 10th in WHIP, and 17th in batting average against. Jesus Luzardo leads Philadelphia in wins with 15 and strikeouts with 216. On Sunday, Philadelphia will hand the ball to Cristopher Sanchez. This season, the left-hander is 13-5 with a 2.57 ERA, 1.08 WHIP, and 204 strikeouts. Sanchez’s ERA is the best for starters on the Phillies.
Minnesota Twins vs. Philadelphia Phillies Pick
Spread Pick for Twins vs. Phillies
- Philadelphia Phillies -1.5 (5 units)
Minnesota has lost seven of its last 10 and six of its last nine against a team from the National League. Philadelphia has won 12 of its last 17, and the Phillies are 14-3 in the last 17 games played at home. Philadelphia is tough against American League opponents, winning nine of the last 10 in that situation. Minnesota's team ERA is 25th at 4.61, while Philadelphia's is 8th at 3.81. Minnesota starter Simeon Woods Richardson has performed well in each of the last two outings, allowing five hits and two runs in 11 innings, resulting in victories over the Yankees and Guardians. However, Philadelphia starting pitcher Cristopher Sanchez has performed well in four of his last five starts, giving up a total of 27 hits and seven runs in 34 innings, holding opponents to one earned run or less in four of the five starts, with Philadelphia winning four of the five. Sanchez has baseball’s fifth-best ERA and 13th-best WHIP.
Over/Under Pick for Twins vs. Phillies
- Wonder (4 units)
The total has finished under in all of Minnesota's last seven and in all of the Twins’ last five on the road, and in four of Minnesota's last six on the road against Philadelphia. As mentioned previously, Philadelphia starter Christopher Sanchez has the fifth-best ERA in baseball at 2.57 and is 13th in WHIP at 1.08.
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