Minnesota Twins vs Tampa Bay Rays Picks and Predictions for Saturday April 25 2026

By: Cameron Ross Published 04/25/2026, 04:45 AM ET
Orioles vs Rays Prediction
Use Code WWWC

The Minnesota Twins will be on the road Saturday for game 2 of 3 inside Tropicana Field in St. Petersburg, FL, at 4:10 PM against the Tampa Bay Rays, and we have you ready to roll with our Minnesota vs Tampa Bay prediction. Minnesota has hovered around .500 thus far this season, coming into this series having lost 4 of the last 5, including 2 in a row after a 2-run road loss against the New York Mets. The Tampa Bay Rays have also hovered around .500 this season, having lost 3 of the last 5 coming into this series, following a 5-run victory against Cincinnati in their last outing. Read more about this Minnesota vs Tampa Bay prediction! Struggling with handicapping? Try our MLB Predictions!

Minnesota looks to get back rolling

Offensively, Minnesota has been below average this season, with a .231 team batting average. The Twins have scored 127 runs on 191 hits. Minnesota has a .331 OBP and a .383 team slugging percentage. The Minnesota pitching has been shaky as well, with a 4.13 team ERA. Joe Ryan got the start for Minnesota in their last outing, giving up 4 runs on 7 hits across 5 innings of work, resulting in a no-decision. Andrew Morris came on in relief to give up 2 runs on 2 hits across 2.2 innings of action, leading to the loss. Ryan Jeffers led the way for the Minnesota offense with 1 hit in 3 at-bats to drive in 4 total runs.

Josh Bell leads the Minnesota offense this season with a .253 batting average and 16 RBI's. Brooks Lee has compiled a .237 batting average, and Victor Caratini has a .250 batting average. Byron Buxton has a .229 batting average and leads Minnesota with 5 home runs this season.

Key Injury Report for Tampa Bay:

Get Free $30 Credit for Premium Picks + Exclusive Discounts

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Winners and Whiners may use third-party services to process my data.
  • Kody Funderburk (Paternity)
  • Cody Lawyerson (15-Day IL)
  • Julian Merryweather (7-Day IL)
  • Cory Lewis (7-Day IL)
  • Travis Adams (15-Day IL)

Tampa Bay tries to defend its home field

Tampa Bay has been solid enough on the offensive side this season, with a .257 batting average. The Rays have scored 116 runs on 214 hits. Tampa Bay has a .333 OBP and a .378 team slugging percentage. Tampa Bay’s pitching has been the team's biggest issue, with a 4.70 team ERA. Nick Martinez got the start for Tampa Bay in their last outing, giving up 1 run on 5 hits across 8 innings of work, leading to the win.  Junior Caminero led the way for the Tampa Bay offense last time out with 1 hit in 4 at-bats to drive in 2 runs.

Yandy Diaz leads the Tampa Bay offense this season with a .340 batting average. Chandler Simpson has a .323 batting average this season through 24 games played. Junior Caminero has a .260 batting average to go along with the team-leading 6home runs. Jonathan Aranda has a .224 batting average but leads Tampa Bay with 19 RBI's this season.

Key Injury Report for Minnesota:

  • Ty Jonson (7-Day IL)
  • Jake Fraley( Day-to-Day)
  • Tj Nichols (7-Day IL)
  • Austin Vernon (7-Day IL)
  • John Rooley (7-Day IL)

Minnesota vs Tampa Bay Pick

  • Minnesota vs Tampa Bay Spread Pick

Both teams have been mediocre thus far this season, coming into Saturday as each is hovering around 500. The Minnesota Twins will have the better pitcher on the mound in this matchup, but the Tampa Bay offense will be the difference. Neither pitcher has a strong ERA, and that will be an issue in this game. Look for Tampa Bay to continue to play well Saturday as they do the job at home against Minnesota. Take the Tampa Bay Rays on Saturday afternoon at home to get the win in Game 2 of this 3-game set.

  • Minnesota vs Tampa Bay Over/Under Pick

Both teams have scored well enough as of late, but each has a pitcher on the mound with a ballooned ERA. Look for both offenses to have a ton of success Saturday as each pitcher will struggle. Expect runs to come in bunches on Saturday in Saint Petersburg as both teams run it up. Take the over on Saturday afternoon as the Minnesota Twins visit the Tampa Bay Rays.

This prediction was written before the completion of game play on Friday.

Never Tried Winners and Whiners? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code DOLLAR
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
  • Check out more MLB predictions
BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Claim Bonus
Signup Promo Recommended BetMGM Sport Bonus
Min. Deposit $5
Cashable No
FanDuel Sportsbook

New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer FanDuel Sportsbook Bonus
Requirement New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days. (Up to $1,000 Bet Reset Tokens)
Cashable No
DraftKings Sport

New DraftKings Customers: Spend $5+ Get $200 in Bonuses Instantly!

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer DraftKings Sport Bonus
Min. Deposit $5
Odds Requirements -500
Cashable No

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright © 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.