New York Mets vs. Detroit Tigers Picks and Prediction for Wednesday, September 3, 2025
It’s the finale of an early week interleague series on the diamond between a pair of squads hoping to solidify their playoff position in the Motor City, as the New York Mets close out a three-game set with the Detroit Tigers Wednesday night and we have you covered with our Mets vs. Tigers prediction. In the opening game of the series Monday night, it was the Mets picking up a 10-8 victory to draw first blood. Which team earns the victory here on getaway day? This article was published prior to the conclusion of the opening game of the series at Comerica Park on Monday afternoon. Read more about this Mets vs. Tigers prediction! Winning isn’t easy so you need the top MLB cappers.
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New York Seeking to Tighten Grip on Playoff Spot
New York won for just the second time in five games as they won a slugfest in the opening game of their set with the Tigers on Monday afternoon. The Mets entered Tuesday 74-64 and stood second in the NL East, six games behind the Phillies for the top spot. They held a four-game lead over the Reds for the final wild card spot in the National League playoff picture. Against Detroit Monday, New York finished with eight hits as Luis Torrens (two runs, two RBI) led the way with three, while Juan Soto (two runs, six RBI) and Jeff McNeil (two runs) each added a pair. Soto (his 36th) went deep in the victory for the Mets. Sean Manaea tossed 3.2 innings, allowing five runs on eight hits with one walk and six strikeouts over 3.2 innings of work, but didn’t factor in the decision. Ryne Stanek (3-6) earned the win as he got the final two outs of the fifth, allowing no runs on no hits with one walk and no strikeouts. Edwin Diaz worked the final 1.1 innings, allowing no runs on no hits with no walks and two strikeouts, for his 25th save.
Clay Holmes is on the mound for the Mets as he makes his 28th start of the season in this contest. He is 11-6 with a 3.60 ERA, a 1.314 WHIP, 56 walks and 111 strikeouts over 142.1 innings of work on the year. Holmes didn’t factor in the decision in his last start, which came at home against the Marlins on Thursday. He threw five innings, allowing four runs (two earned) on five hits with one walk and two strikeouts in a game the Mets dropped 7-4. In his last three starts, Holmes is 2-0 with a 2.76 ERA, a 1.04 WHIP, four walks and 10 strikeouts over 16.1 innings of work. Holmes makes his 14th career appearance, first start against the Tigers in this contest. He has no record with four saves, a 3.46 ERA, a 1.077 WHIP, two walks and 19 strikeouts over 13 innings of work. Holmes has no record with one save, a 5.40 ERA, a 1.35 WHIP, two walks and 10 strikeouts over 6.2 innings of action in seven career appearances, all in relief, at Comerica Park.
Tigers Hoping to Get on Track
Detroit fell for the sixth time in eight games as they were downed in the opening game of the series Monday afternoon. The Tigers improved to 80-59 on the year and entered Monday with a massive nine-game lead on the Royals in the AL Central. Against New York, Detroit rapped out 14 hits in a losing effort as Jahmai Jones (two runs, two RBI) leading the way with four. Jones (his fifth) and Wenceel Perez (his 12th) each homered for the Tigers, who went two of 14 with runners in scoring position in the game. Charlie Morton threw 3.2 innings, allowing six runs on five hits with four walks and three strikeouts, but didn’t factor in the decision. Drew Sommers (0-1) took the loss in relief as he allowed three runs on two hits with no walks and one strikeout in one inning of relief.
Casey Mize gets the ball on getaway day as he makes his 24th start of the season for the Tigers here. He is 12-5 with a 3.95 ERA, a 1.309 WHIP, 32 walks and 107 strikeouts over 120.2 innings of work this season. Mize took the loss in his last start, which came against the Athletics last Wednesday on the road. He threw 3.1 innings, allowing five runs on seven hits with two walks and four strikeouts in a 7-0 Tigers loss. In his last three starts, Mize is 1-1 with a 7.04 ERA, a 1.57 WHIP, four walks and 14 strikeouts over 15.1 innings of work. Mize didn’t factor in the decision in his lone career start against the Mets, which came on the road in the first game of a doubleheader on the road April 4, 2024. He threw 4.1 innings, allowing three runs on five hits with two walks and four strikeouts in a game the Tigers won 6-3 in 11 innings. Mize is 10-12 with a 4.20 ERA, a 1.272 WHIP, 52 walks and 150 strikeouts over 195 innings of work in 41 career appearances, 39 starts, at Comerica Park.
Detroit Tigers ML (4 units)
Monday’s opener was a slugfest as the teams combined for 18 runs in a Mets’ triumph. The pitching matchup for this contest you would have to lean to the Tigers here as Mize was pitching well prior to getting roughed up in Sacramento in his last outing. Mize is 7-1 with a 3.61 ERA and a 1.19 WHIP over 57.1 innings of work in 11 starts at Comerica Park this season. Holmes won two of his last three starts but he’s increasingly become a five-and-dive guy. In eight of his last 10 starts, he has gone five innings or less in eight of them and went just 5.1 innings in one of the others. Look for the Tigers to find a way to claw their way to a victory here on getaway day.
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Earle Sports Bets | +2,298.00 |
| 2 |  Ross Benjamin | +1,840.00 |
| 3 |  Rob Vincilleti | +1,757.00 |
| 4 |  David Hess | +1,745.00 |
| 5 |  Dan Kaiser | +987.00 |
Over (4 units)
The Mets are tied for 9th in runs per game with 4.78 runs a night, a number that edges down slightly to 4.60 runs per game on the road entering Tuesday night. New York has an average total of 9.09 runs per game and that slips to 9.05 runs per game on the road. The Mets entered Monday having seen the under post a 66-65-7 mark in their opening 137 games of the year. Detroit has seen the over post a 71-60-8 mark on the season entering Tuesday. The Tigers are 8th with 4.81 runs per game, a number that jumps to 5.11 runs per game at home. Detroit allows 4.18 runs per game, giving them an average total of 8.99 runs per game. That number jumps to 9.27 runs per game at home on the year. After the offensive outburst in the opening game of the series, look for this game to wind up over the total.
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