New York Yankees vs. Minnesota Twins Picks and Prediction for Wednesday, September 17, 2025
Use Code WWWC New York Yankees (83-67) vs. Minnesota Twins (66-84)
The 2025 Major League Baseball season goes on Wednesday, September 17, with the New York Yankees taking on the Minnesota Twins in the American League showdown at Target Field in Minneapolis, Minnesota, and we’ve got you covered with our Yankees vs. Twins prediction.
New York meets Minnesota for the sixth and final time this season, as they wrap up a three-game series at Target Field. Last month, the Yankees took two out of three games against the Twins at Yankee Stadium. The Twins blanked the Yanks 7-0 in the opening game of this series, while the middle game has been excluded from the analysis.
Let’s take a closer look at this Yankees vs. Twins prediction, one of our MLB picks for Wednesday’s slate. The first pitch at Target Field is set at 7:40 PM ET, and the Yankees are -180 moneyline favorites with a total of 9.0 runs.
The Yankees lean on Luis Gil
The New York Yankees mustered just two hits at Target Field last Monday. It was an awful offensive display, while Luke Weaver gave up five earned runs in relief and got one out. Yet, Carlos Rodon took a loss, throwing six frames of a two-run ball.
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The Yankees have been a hit-or-miss lately, going 5-5 in their previous 10 games overall. They are slashing .228/.301/.414 with 21 home runs in September (425 at-bats), while the Yankees bullpen has amassed a 4.21 ERA, 1.28 WHIP, and a .207 batting average against.
Luis Gil is expected to take the mound at Target Field on Wednesday. The 27-year-old right-hander is 4-1 with a 2.83 ERA and 1.40 WHIP in eight starts (41.1 innings pitched) this season. After allowing five earned runs in his season debut on August 3, Gil has pitched lights out, posting a 1.89 ERA across 38 frames of work.
Gil is 1-0 with a 3.75 ERA in two career starts against the Twins. Just three guys from this Minnesota team have seen Gil before, combining for a single and a home run in eight at-bats.
The Twins need more from Taj Bradley
The Minnesota Twins dominated the Yanks last Monday. The Twins scored seven runs on nine hits and five walks, while Simeon Woods Richardson struck out a career-high 11 across six innings. Austin Martin had a big game, too, driving in four runs.
The Twins have only won four of their previous 14 games overall. They are hitting .257/.333/.424 with 17 home runs in September (486 at-bats), while their bullpen has compiled a 3.57 ERA, 1.30 WHIP, and a .249 batting average against.
Taj Bradley is projected to get the starting call on Wednesday night. The 24-year-old right-hander carries a 6-7 record with a 4.88 ERA and 1.30 WHIP in 25 starts (132.2 IP) between Tampa Bay and Minnesota in 2024. Over four outings with the Twins, Bradley has struggled a lot, yielding 15 earned runs on 22 hits and seven walks through 21.1 innings of work.
Bradley is 2-2 with a 3.42 ERA in four career starts against the Yankees. He’s already met them twice this season, surrendering eight earned runs on 13 hits and seven walks across 10.2 innings. The current Yanks are 13-for-56 with two doubles and a home run against Bradley.
Yankees vs. Twins Pick
Spread Pick for Yankees vs. Twins
- New York Yankees -1.5 (5 units)
Taj Bradley has allowed seven earned runs over his last two starts. The Yankees know him very well, so it’s hard to trust Bradley in this matchup. On the other hand, Luis Gil has been outstanding lately, and many players from this Minnesota team will be seeing him for the first time.
I expect Gil to outpitch Bradley and make a difference. The Twins are 0-4 in Bradley’s four starts, while the Yankees have emerged victorious in three of Gil’s previous four starts.
Moreover, it’s the closing contest of a three-game series, and the Yankees' bullpen is arguably deeper than the Twins ‘pen.
Over/Under Pick for Yankees vs. Twins
- Under 9.0 (5 units)
Both lineups have done a good job over the last 10 days, though the Yankees certainly expect more from their bats. Anyway, the Yanks will meet Taj Bradley on Wednesday night, whom they know from his time with the Tampa Bay Rays.
I’m backing the Yankees to get to Bradley early and force the Twins to lean on their bullpen. On the other side, I’m looking for a dominant performance from Luis Gil. The line is sitting at 9.0 runs at the moment, so I have to take the under. Should Gil continue to impress, this game won’t produce runs in double digits.
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