New York Yankees vs San Francisco Giants Picks and Prediction for Saturday, March 28, 2026

By: David Anicetti Published 03/28/2026, 04:15 AM ET
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The New York Yankees (1-0) visit the San Francisco Giants (0-1) at Oracle Park on Saturday at 7:15 PM ET on MLB.TV/FOX. New York opened the series with a 7-0 win on Wednesday behind strong pitching and timely hitting, while San Francisco looks to respond after being held scoreless. This preview was written before the completion of Fridayโ€™s game. San Francisco is listed as a slight home favorite with the total trending around 8.5. Be a winner with our free MLB picks.

New York Yankees: Balanced Attack Early

New York started the season with a complete performance, combining strong pitching with consistent offense throughout the lineup. The Yankees scored seven runs on 10 hits in the opener, showing the ability to build offense across multiple innings rather than relying on one stretch. That type of production sets the tone early in a series.

Giancarlo Stanton and Cody Bellinger provide power in the middle of the order, while Aaron Judge remains a central presence even after a quiet opening performance. Austin Wells and Ryan McMahon contributed early production, showing the depth of the lineup beyond the top names. Jazz Chisholm Jr. adds speed and versatility, giving New York multiple ways to create scoring chances.

The Yankeesโ€™ offensive approach is built on patience and situational hitting. New York worked counts and capitalized on opportunities with runners on base in the opener, going 4-for-11 in those spots. That ability to convert chances without needing home runs gives the lineup consistency across full games.

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New York enters with some key injuries that affect both the rotation and depth. Gerrit Cole, Carlos Rodรณn, and Clarke Schmidt are all unavailable, while Anthony Volpe remains out as well. Rafael Montero is day-to-day

San Francisco Giants: Need Better Execution

San Francisco enters at 0-1 after struggling to generate offense in the opener, managing just three hits and failing to score. The Giants had limited opportunities and were unable to produce in key situations, going 0-for-5 with runners in scoring position. That lack of execution needs to improve quickly.

Luis Arraez provides a strong contact presence at the top of the lineup, while Rafael Devers and Matt Chapman offer run production in the middle. Willy Adames adds power potential, and Jung Hoo Lee brings another bat that makes contact. This lineup has the players to generate offense, but it needs better hitting with runners in scoring position.

The Giants are not built around power. San Francisco relies on putting the ball in play, working counts, and creating opportunities through contact. When that approach is working, the lineup can sustain rallies and apply pressure. The opener showed that without execution, those opportunities can disappear quickly.

At home, San Francisco should be more aggressive early in counts to establish rhythm. Generating early base runners and avoiding extended scoring droughts will be key against a Yankees team that can control games once ahead.

The Giants also have several bullpen injuries that impact depth. Joel Peguero and Sam Hentges are on the 15-day IL, while Reiver Sanmartin and Jason Foley remain out long-term. Those absences could limit late-game bullpen options.

Pitching Matchup

New York Yankees โ€“ Will Warren

Warren went 9-8 with a 4.44 ERA and 1.37 WHIP last season. He can generate strikeouts but can allow baserunners, which can create pressure if innings extend.

San Francisco Giants โ€“ Tyler Mahle

Mahle finished 6-4 with a 2.18 ERA and 1.13 WHIP. He limits hard contact and has shown the ability to keep runs down, especially when working ahead in counts.

New York Yankees vs San Francisco Giants Pick

  • New York -138

New York enters with momentum and more production at the plate after the opener. The Yankees showed the ability to generate runs across multiple innings, while San Francisco struggled to produce offense. Mahle gives the Giants a chance to stabilize, but New Yorkโ€™s lineup depth creates more pressure over the course of the game. The Yankees are the stronger side based on current form and overall talent.

New York Yankees vs San Francisco Giants - Over/Under Pick

  • Over 9.0

The total is set at 9.0, and this matchup presents mixed signals. San Francisco should improve offensively at home, while New York has already shown it can generate runs without relying on power. At the same time, Mahleโ€™s ability to limit damage could slow scoring early. With both teams capable of creating opportunities, the over is a reasonable play, especially if the Giants contribute more offensively than in the opener.

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