Philadelphia Phillies vs. Miami Marlins Picks and Prediction for Saturday, September 6

By: Chris King Published 09/06/2025, 06:36 AM ET
Phillies vs. Marlins Prediction
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Itโ€™s the middle game of a three-game series between National League East foes on the diamond in South Beach as the Philadelphia Phillies travel to face the Miami Marlins Saturday afternoon, and we have you covered with our Phillies vs. Marlins prediction. Philadelphia took two of three from Milwaukee on the road in a battle of division leaders as they picked up a 2-0 win in the rubber game on Thursday. Miami was swept on the road by Washington, falling 10-5 on Wednesday in the finale. This article was published before the conclusion of the opening game of the set at LoanDepot Park on Friday night. Donโ€™t go down on strikes! Increase your bankroll with our MLB Betting Picks! Read more about this Phillies vs. Marlins prediction!

Phillies Seeking to Extend NL East Advantage

Philadelphia won the rubber game of their set by blanking the Brewers on the road in the finale of that set on Thursday. The Phillies entered Friday 81-59 and held a six-game lead over the Mets for the top spot in the NL East. Against Milwaukee on Thursday, Philadelphia finished with six hits with no player having more than one. The Phillies were two of 11 with runners in scoring position but managed to do enough to earn the victory. Ranger Suarez (11-6) earned the win with six scoreless innings, allowing six hits with two walks and four strikeouts, before departing. Jhoan Duran worked a 1-2-3 ninth, striking out one, for his 26th save of the year.

Jesus Luzardo gets the ball for the Phillies as he makes his 29th start of the season in this contest. He is 12-6 with a 4.05 ERA, a 1.285 WHIP, 52 walks and 182 strikeouts over 155.2 innings of work this season. Luzardo didnโ€™t factor in the decision in his last start, which came against the Braves at home Sunday. He threw 6.2 innings, allowing no runs on two hits with one walk and seven strikeouts in a 3-1 Phillies defeat. In his last three starts, Luzardo is 1-0 with a 2.70 ERA, a 0.84 WHIP, four walks and 24 strikeouts over 16.2 innings of work. Luzardo makes his third career start against the Marlins in this contest. He is 0-1 with a 3.75 ERA, a 1.50 WHIP, four walks and 11 strikeouts over 12 innings of work against them. Luzardo is 13-15 with a 4.10 ERA, a 1.22 WHIP, 84 walks and 269 strikeouts over 239.1 innings in 44 career starts at LoanDepot Park.

Miami Looking to Prevail at Home

Miami was swept on the road against the Nationals with Wednesdayโ€™s loss, wiping away the momentum after taking three of four from the Mets. The Marlins entered Friday 65-75 and stood third in the NL East, 16 games behind the Phillies for the top spot. They were 10 games behind the Mets for the final playoff spot in the National League. Against Washington Wednesday, Miami finished with 10 hits as Joey Wiemer (run, two RBI) and Jakob Marsee each had a pair. Wiemer (his first) went deep in the loss for the Marlins. Eury Perez (6-5) took the loss as he allowed seven runs on eight hits with one walk and two strikeouts over four innings of work.

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Sandy Alcantara is on the bump for the Marlins as he makes his 28th start of the season in this contest. He is 8-11 with a 5.66 ERA, a 1.318 WHIP, 52 walks and 119 strikeouts over 148 innings of work on the season. Alcantara earned the win in his last start, which came against the Mets on the road Sunday. He threw seven innings, allowing one run on four hits with one walk and six strikeouts in a game the Marlins won 5-1. In his last three starts, Alcantara is 2-0 with a 1.71 ERA, a 0.76 WHIP, four walks and 22 strikeouts over 21 innings of work. Alcantara makes his 22nd career start against the Phillies in this contest. He is 6-10 with a 3.78 ERA, a 1.236 WHIP, 34 walks and 113 strikeouts over 128.2 innings of work against them. Alcantara is 24-31 with a 3.19 ERA, a 1.074 WHIP, 145 walks and 463 strikeouts over 530.2 innings of action in 81 career appearances starts at LoanDepot Park.

Phillies vs. Marlins Pick

Run Line Pick for Phillies vs. Marlins

  • Phillies -1.5 (+110) (4 units)

Alcantara has been better of late, going 4-2 with a 3.16 over 57 innings of work in nine starts since the All-Star break. With that said, the Marlins arenโ€™t as dangerous offensively at home as they are on the road this season. Luzardo has been solid of late and the Phillies are looking to chase down Milwaukee for the top record in the National League. The Phillies have a loaded lineup and they are looking to take care of business against teams below them in the standings. Look for Philadelphia to come up with the road victory as they rough up Alcantara here to earn the win.

Over/Under Pick for Phillies vs. Marlins

  • Under 8 (4 units)

Philadelphia has seen the under post a 72-59-9 mark on the year entering Friday. The Phillies are 10th in the majors with 4.75 runs per game and that number falls to 4.18 runs per game away from Citizens Bank Park. Philadelphia has an average total of 8.79 runs per game but that number drops to eight runs per game on the road. Miami has gone over the number in 69 of their 140 games, with four pushes, on the season entering Friday night. The Marlins are 18th in the majors with 4.33 runs per game, a number that slips down to 3.79 runs per game at home. Miami has an average total of 9.32 runs per game and that number slides down to 8.50 runs per game at home this season. Look for this game to wind up falling under the total as both pitchers do a solid job here.

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