Pittsburgh Pirates vs. Baltimore Orioles Picks and Prediction for Tuesday, September 9th, 2025

By: Adam Rauzino Published 09/09/2025, 11:16 AM ET
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The Pittsburgh Pirates (64-80, 77-67 RL, 59-80-5 O/U) and the Baltimore Orioles (66-77, 72-71 RL, 61-75-7 O/U) begin a three-game series on Tuesday evening, and we have the prediction. The Pirates are sending Mike Burrows to the rubber. The Orioles will have Kyle Bradish on the mound.Β  The Pirates went 2-1 against the Orioles last season.

Can Kyle Bradish earn his first win of the season on Tuesday? Check out the Pirates vs. Orioles prediction. Nobody does it better when it comes toΒ MLB Picks!

Pirates Dealt Sweep by Brewers

Mike Burrows is on the rubber on Tuesday evening. Burrows has been pitching bulk innings. He was sharp in his recent outing,Β  posting three scoreless innings against the Dodgers, and was awarded the win. The rookie has only conceded six runs in his past 18 innings of work and has recorded a 4.08 ERA and a 1.26 WHIP, accompanied by a 2-4 record in 81.2 innings on the season. This is his first meeting against the Orioles. There is a good chance Braxton Ashcraft will pitch after Burrows. Ashcraft is enjoying a magnificent season, posting a 2.44 ERA and a 1.19 WHIP accompanied by a 4-2 record in 55.1 innings.

The Pittsburgh Pirates begin a road trek in this one. The squad has been competitive recently. They swept the Dodgers last week but could not keep the momentum intact. They were charged with a sweep at the hands of the Brewers on the weekend. They conceded 19 runs in the series in Milwaukee. The Pirates are 22-47 on the road.

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Oneil Cruz has just four RBIs in his past 10 games. The 26-year-old is having an inconsistent season. He has managed 56 RBIs and a .686 OPS on the season. Bryan Reynolds has been a tough out, amassing a sharp .985 OPS in September. The veteran slugger is having another strong year, bashing 20 home runs with 70 RBIs.He did not record an RBI against Pittsburgh last season. Spencer Horwitz enjoyed a big August but has zero RBIs this month. The first baseman has recorded 39 RBIs and a .722 OPS on the year. Nick Gonzales has managed only RBI in the past five games. The 25-year-old has issued a decent .700 OPS.

Pittsburgh is only averaging 3.62 runs per game on the season, ranking them 30th. The pitching staff has a strong 3.91 ERA, placing them 11th.

Bradish Expected to Get the Nod on Tuesday

Kyle Bradish is expected to be on the mound on Tuesday. Bradish has missed nearly one year due to Tommy John recovery. He made his return a few weeks ago and conceded two runs in six innings against the Red Sox. Next, he squandered two runs in four innings against the Padres earlier this month, resulting in a no-decision in a game the Orioles won. That totals to four runs in 10 innings on the season. The veteran is proven. He has recorded a 3.57 ERA and a 1.07 WHIP in 335.2 career innings in the big leagues. Bradish conceded one run (zero earned) in his only career meeting against Pittsburgh.

The Baltimore Orioles are in the middle of a homestand. Baltimore has been dangerous recently, winning two consecutive series. They recorded a surprising road sweep of the Padres last week. Next, the Orioles won two of three home clashes against the Dodgers, aided by the pitching, keeping them to only nine runs in the series. The Orioles are 33-38 at home.

Gunnar Henderson has issued a .436 OPS early this month. The 24-year-old shortstop has clubbed 16 big flies with 61 RBIs on the year.Β  Coby Mayo has netted a decent .733 OPS in September. The rookie first baseman has recorded 21 RBIs and a .603 OPS. Ryan Mountcastle has missed more than half the season due to injury. The veteran first baseman is in a groove, amassing seven RBIs in his past eight games, and has 30 RBIs and a .673 OPS on the season. He knocked in one run against the Pirates last season. Jordan Westburg is dealing with an injury and remains out.

Baltimore is scoring an average of 4.35 runs on the season, marking them 16th. The pitching staff is a weakness, reporting a 4.66 ERA, which ranks them 25th.

Baltimore Orioles vs. Pittsburgh Pirates Pick

Spread Pick for Orioles vs. Pirates

  • Pittsburgh Pirates +1.5

The Pittsburgh Pirates have been competitive. They have won three of their past five series. This includes a series win against the Blue Jays and a dominating sweep of the Dodgers. They held the Dodgers to just 10 runs. The Baltimore Orioles have only won two of their last five series. They stand at 2-3 in their past five home games.

Furthermore, Pirates starting pitcher Mike Burrows has been sharp, yielding only three runs in his past 14 innings of work.Β  He usually pitches about three innings. Braxton Ashcraft is expected to follow. Ashcraft has also been on his game, conceding three runs in his past 23.2 innings pitched. Orioles pitcher Kyle Bradish is making his third start since recovering from Tommy John. He only pitched four innings in his recent outing.Β  Three of the Orioles’ past five wins have been by just one run.

Over/Under Pick for Orioles vs. Pirates

  • Over

I expect plenty of scoring. Pittsburgh has averaged 4.0 runs in its past 10 games, above its season average. I don’t expect Bradish to pitch deep into the game, and the Orioles' bullpen has reported a weak 4.50 ERA on the season, ranking them 24th.

In addition, Baltimore is in a groove at the dish. They have averaged 4.7 runs in their past 10 games, including series against the Red Sox and Padres. Burrows has issued a subpar 4.15 ERA on the road. The Pirates have surrendered 29 runs in their past six games. The over is 5-0 in the Pirates' past five Tuesday games.

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