Pittsburgh Pirates vs Chicago Cubs Picks and Predictions for Saturday, April 11, 2026
Use Code WWWC The Pittsburgh Pirates will be on the road again Saturday for game two of three in Chicago against the Chicago Cubs in Wrigley Field at 2:20 PM, and we have you ready to roll with our Pittsburgh vs Chicago prediction. Pittsburgh comes into this matchup with eight wins and five losses on the season. Chicago stays at home Saturday with six wins and seven losses this year. The Pirates have won three of the last five following the two-run victory in Game 1 of this set. Chicago has lost three of the last five after losing Game 1 of this series to end a 2 game-winning streak. Read more about this Pittsburgh vs Chicago prediction! Struggling with handicapping? Try our MLB Predictions!
Pittsburgh looks to keep it going
Offensively, Pittsburgh has a .247 team batting average to go along with 54 runs on 100 hits this season. The Pirates offense has a .338 team OBP and a .383 team slugging percentage. The Pittsburgh bullpen has been phenomenal this season with a 3.33 team ERA, and Pittsburgh has allowed three total runs across its last three victories. Carmen Mlodzinski got the start last time out for Pittsburgh, giving up no runs on six hits across 5.1 innings of work, resulting in a no-decision. Madison Montgomery came on and relieved to give up no runs on no hits, resulting in the win. Bryan Reynolds led the way for the Pittsburgh offense with one hit and four at-bats to drive in both runs of the game.
Ryan O’Hearn leads the Pittsburgh offense this season with a .341 batting average. O'Neill Cruz has chipped in with a .300 batting average to go along with the team-leading four home runs and twelve RBI's. Bryan Reynolds has a .245 batting average, and Nick Gonzales has added a .273 batting average this season.
Key Injury Report for Pittsburgh:
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- Anthony Solometo (Day-To-Day)
- Jared Triolo (10-Dauy IL)
- Jared Jones (60 -Day IL)
- Oddanier Mosqueda (60-Day IL)
Chicago looks for a home win
Offensively, Chicago has been below average this season with a .223 team batting average. The Cubs have scored 56 runs on 87 hits this far this season. Chicago has a .312 OP and a .368 team slugging percentage. Chicago has a 3.43 team ERA but has given up 14 runs across their last four losses. Shota Imanaga got the start for Chicago in their last outing, giving up no runs on no hits across 6 innings of work. Caleb Thielbar came on and relieved to give up two runs on three hits after recording only two outs, leading to the loss. The Chicago offense struggled immensely, combining for six hits in 31 at-bats.
Nico Hoerner leads the Chicago offense this season with a .326 batting average and nine RBI's. Pete Crow-Armstrong has a .216 batting average, and Michael Busch has struggled immensely this season with a .125 batting average. Ian Happ has a .233 batting average and leads Chicago this season with four home runs
Key Injury Report for Chicago:
- Ian Happ (Day-To-Day)
- Trent Thornton (7-Day IL)
- Jeff Brigham (7-Day IL)
- Jaxon Wiggins (Day-To-Day)
- Jordan Wicks (15-Day IL)
Pittsburgh vs Chicago Pick
- Pittsburgh vs Chicago Spread Pick
Pittsburgh is playing better baseball coming into this matchup and will have a strong arm on the mound. Look for Pittsburgh to ride their starter as their offense is the better unit. Take Pittsburgh Saturday to continue their winning ways; they overwhelm a struggling Chicago team for 9 innings. Take the Pirates to the job as they get the win on the road as the underdog Saturday in Chicago.
- Pittsburgh vs Chicago Over/Under Pick
Both teams have mediocre pitchers on the mound, and each has a solid enough offense. Look for more of an offensive explosion in Game 2 of this series on Saturday. Look for both teams to score consistently throughout Saturday's matchup, leading to runs and bunches. Take the over on Saturday as the Pittsburgh Pirates again visit the Chicago Cubs.
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