San Diego Padres vs. Baltimore Orioles, Picks and Prediction, Friday, June 12, 2026
Use Code WWWC San Diego (35-32) will be trying to pick up their second consecutive series win when they visit Oriole Park at Camden Yards to face Baltimore (32-37) in the first game of their three-game interleague series at 7:05 PM. ET. Read on to find out which team picks up the win in this Padres vs. Orioles prediction. Need some winners this baseball season? Check out our Free MLB Picks.
Griffin Canning, 0-4, 6.34 ERA, will get the start for the Padres. The Orioles will counter with Shane Baz, 3-6, 4.09 ERA.
Baltimore is 6-4 in its last 10 games against San Diego.
**This preview was written before Thursday’s game was played.**
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Padres Trying To Move Up NL West Standings
The Padres snapped their four-series losing streak with a series win over the Reds. They are second in the NL West standings, 7.5 games behind the Dodgers, and will try to cut into Los Angeles’ lead with a win on Friday.
San Diego averages 3.81 runs per game, which is 30th in the league. Their .218 batting average is 30th in the league. Their .291 on base percentage is also the worst in the league, as is their .360 slugging percentage.
Fernando Tatis Jr. leads the Padres with a .281 batting average, while Manny Machado leads the team with 11 home runs and 34 RBI.
San Diego is giving up 4.03 runs per game, which is seventh in the league. Opponents have a .238 batting average against the Padres, which is 11th in the league. Their 3.90 ERA is ninth, while their 1.28 WHIP is 12th.
In his last start, Canning gave up three hits and one run in five innings, leading to a 3-2 win over the Mets. He is 1-4 with a 9.49 ERA in six games against Baltimore.
Orioles Trying To End Slump
The Orioles followed up their series win over Boston with four losses in their last six games, dropping them five games under .500. They will try to turn things around and take the series lead when they play on Friday night.
Baltimore averages 4.70 runs per game, which is eighth in the league. Their .241 batting average is 17th in the league. Their .322 on base percentage is 13th, while their .400 slugging percentage is 10th.
Taylor Ward leads Baltimore with a .261 batting average, while Pete Alonso leads the team with 14 home runs and 42 RBI.
Baltimore is giving up 5.13 runs per game, which is 28th in the league. Opponents have a .262 batting average against the Orioles, which is 29th in the league. Their 4.56 ERA is 23rd, while their 1.40 WHIP is 24th.
In his last start, Baz gave up seven hits and five runs in 5.2 innings, leading to a 6-4 loss to Toronto. He is 2-0 with a 1.80 ERA in two games against the Padres.
Padres vs. Orioles Picks
Money Line Pick for Padres vs. Orioles
- Baltimore Orioles ML (4 Units)
The Orioles have the edge in this game because they’re playing well offensively, and scored 15 runs in their last three home games. They’ve had a lot of success against right-handers, and they’re going up against Canning, who hasn’t been very good on the mound this season, especially on the road, where he gave up nine runs in two starts. He gave up eight runs in his last two road starts against the Orioles, so expect them to play well offensively in this game.
The Padres will have a hard time keeping up offensively because they’re the worst offensive team in the league, and they didn’t play well in recent games, scoring eight runs in their last three road games. They have struggled against right-handers, and they’re facing Baz, who has done well on the mound at home, giving up seven runs in his last three home starts. He gave up two runs in two starts against the Padres and will keep their offense in check. Take Baltimore on the money line.
Over/Under Pick for Padres vs. Orioles
- Under (4 Units)
The Padres average 3.81 runs per game. They’re batting .217 against right-handers, and they’re facing a starter who gave up two runs in two starts against them. The Orioles average 4.70 runs per game. They’re batting .247 against right-handers, and they’re facing a starter who gave up seven runs in his last three starts. Don’t expect these teams to score enough runs to push the score over the total.
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