San Diego Padres vs. Miami Marlins Picks and Prediction for Saturday July 25 2026

The San Diego Padres visit the Miami Marlins on Saturday at 4:10 PM ET at loanDepot Park in Miami, Florida. San Diego is 50-53 and sits third in the NL West, 15 games behind the Dodgers. The Padres have lost three of their last five games, including back-to-back one-run defeats against Atlanta, and are looking to get back on track. Miami is 52-51 and sits tied for third in the NL East, 8.5 games behind Atlanta. The Marlins have dropped five straight games after being swept on their recent road trip but return home with a 31-20 record at loanDepot park. Be a big winner with our free MLB picks.

San Diego Padres Looking to End Their Losing Streak

San Diego is batting .230 while scoring 426 runs with 779 hits, 115 home runs, a .307 on-base percentage, and a .383 slugging percentage. Manny Machado leads the club with 22 home runs and 59 RBIs, while Fernando Tatis Jr. is batting .286 with a team-high 114 hits. Ty France has added 16 home runs with a .275 batting average, and Gavin Sheets has contributed 14 home runs. The Padres have enough power to stay competitive, but consistent run production has been difficult to find throughout the season.

San Diego owns a 4.25 ERA and a 1.34 WHIP while opponents are batting .248 against its pitching staff. JP Sears gets the start with a 2-3 record, a 4.38 ERA, and a 1.26 WHIP across 24.2 innings. Sears has allowed 23 hits while striking out 20 batters and walking eight. The Padres need Sears to keep Miami's lineup in check if they hope to snap their recent slide.

Injuries: Samad Taylor (10-Day IL), David Morgan (15-Day IL), Jeremiah Estrada (15-Day IL), Lucas Giolito (15-Day IL), Nick Pivetta (60-Day IL).

Miami Marlins Looking to Bounce Back at Home

Miami is batting .251 while scoring 457 runs with 861 hits, 104 home runs, a .326 on-base percentage, and a .406 slugging percentage. Otto Lopez leads the offense with a .332 batting average and 131 hits, while Liam Hicks has produced 14 home runs and 60 RBIs. Xavier Edwards is batting .290 with a .372 on-base percentage, and Kyle Stowers has added 12 home runs. The Marlins have been one of the better contact-hitting teams in the National League and have played much better at home this season.

Miami has recorded a 4.05 ERA and a 1.25 WHIP while holding opponents to a .230 batting average. Eury Perez takes the mound with a 5-7 record, a 3.53 ERA, and a 1.11 WHIP across 91.2 innings. Perez has allowed only 65 hits while striking out 104 batters. His ability to miss bats gives Miami an advantage against a Padres lineup that has struggled for consistent offense.

Injuries: John King (15-Day IL), William Kempner (15-Day IL), Josh Ekness (60-Day IL), Owen Caissie (10-Day IL), Max Meyer (15-Day IL).

Pitching Matchup

San Diego Padres – JP Sears

Sears is 2-3 with a 4.38 ERA and a 1.26 WHIP across 24.2 innings. He has allowed 23 hits while striking out 20 batters and issuing eight walks. The left-hander has shown flashes of solid pitching but faces a challenging matchup against a Miami lineup that has been productive at home.

Miami Marlins – Eury Perez

Perez is 5-7 with a 3.53 ERA and a 1.11 WHIP over 91.2 innings. He has surrendered only 65 hits while recording 104 strikeouts, showing the ability to limit hard contact and generate swings and misses. Perez gives Miami a dependable option as the Marlins try to end their losing streak.

San Diego Padres vs. Miami Marlins Game Pick

• Miami Marlins

Miami has the edge with the stronger offense, a better home record, and the more favorable starting pitching matchup. Perez has produced better numbers than Sears and has consistently limited opposing hitters throughout the season. The Marlins have also been much more comfortable at loanDepot Park despite their recent losing streak, while San Diego has struggled to score regularly. Expect Miami to take advantage of its home field and stronger lineup to get back into the win column with a solid all-around performance.

San Diego Padres vs. Miami Marlins Over/Under Pick

• Under

Perez has been one of Miami's most reliable starters, and San Diego has averaged just 426 runs through 103 games this season. The Padres have struggled to string together consistent offense, while Miami has relied on pitching to stay competitive during many of its games. With two teams trying to stop recent losing streaks, expect few runs early before the bullpens take over. The stronger pitching matchup will produce another game that cashes below the total.