San Diego Padres vs Seattle Mariners Picks and Prediction for Sunday May 17 2026

By: Dylan Hellebrand Published 05/17/2026, 05:05 AM ET
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The San Diego Padres, sitting at 26–18, head to Seattle for a matchup with the Mariners (22–24) at T-Mobile Park. Seattle will be trying to snap out of its recent skid and get back on track with a much-needed win in this interleague showdown. Get involved in the action with our free MLB picks.

San Diego vs Seattle Game Information

  • May 17, 2026
  • 7:20 PM EST
  • T-Mobile Park
  • NBC/Peacock

Seattle Form & Recent Results

Seattle heads into this matchup trying to bounce back after a tough one-game skid, though they’ve still been playing solid baseball overall, taking three of their last five contests leading into Saturday. Friday night’s 2–0 defeat against San Diego came at home, and despite the shutout, the Mariners actually got a quality start from Emerson Hancock. The right-hander went six innings, gave up five hits and just one earned run, and kept damage to a minimum by issuing only one walk while striking out six. Seattle just couldn’t come up with the timely hit they needed to push runs across.

Offensively, Luke Raley has been one of the biggest power threats on the roster, leading the team with 10 home runs, and he’s also their top run producer with 27 RBIs. Cal Raleigh and Julio Rodríguez are close behind in the long-ball department, each sitting at seven homers on the season, giving Seattle a few different sources of pop throughout the lineup. For pure consistency at the plate, Randy Arozarena has been their most reliable hitter in terms of average, pacing the club at .305. Over their last five games, the Mariners have put up 4.8 runs per game on average, and they’ll be aiming to turn that into a win on Sunday as they try to avoid dropping another home game to the Padres.

San Diego Form & Recent Results

San Diego comes into this matchup riding a one-game winning streak, and they’ve put together three wins in their last five games heading into Saturday. They picked up a 2–0 road victory over Seattle on Friday, leaning on a strong all-around performance and timely hitting. Designated hitter Miguel Andújar led the way at the plate by going 2-for-4, driving in one run and coming around to score another. On the mound, starter Randy Vásquez delivered exactly what the Padres needed, working six innings while giving up just four hits and zero earned runs. He didn’t issue a single walk and finished with three strikeouts, keeping Seattle’s offense under control throughout his time in the game.

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Even with the shutout win, the Padres’ offense wasn’t exactly explosive, though they did collect nine hits and totaled ten bases, but they also left six runners stranded. Over the full season so far, shortstop Xander Bogaerts has been their top power threat with seven home runs, while Manny Machado and Gavin Sheets sit right behind him with six each. Bogaerts has also been their most productive run creator, leading the team with 23 RBIs. Andújar has been their most consistent hitter overall, pacing the club with a .297 batting average. Still, the bigger concern is run production lately, as San Diego is averaging just 2.6 runs over their last five games, and they’ll need that number to climb if they want to stay in the mix with the Dodgers in the division heading into Sunday night against Seattle.

Key Stats

  • San Diego’s Xander Bogaerts this season: 7 HRs, 23 RBIs, .263 AVG
  • Seattle’s Luke Raley this season: 10 HRs, 27 RBIs, .265 AVG

Betting Odds & Market Overview:

  • SEA -157 / SD +130; O/U 7.5

San Diego vs Seattle Picks and Prediction

Seattle will hand the ball to right-hander George Kirby, who’s been sharp so far at 5–2 with a 2.84 ERA. San Diego will counter with Lucas Giolito, making his first appearance as a starter this season. The Padres’ bats haven’t shown much life recently, and the lineup has looked stuck in neutral, so Seattle will see this as a chance to press the issue. If the Mariners are going to capitalize, the best path is to attack Giolito right away, make him work from the stretch, drive up his pitch count, and force San Diego’s bullpen into the game earlier than they’d like. Final Score Prediction, Seattle Mariners win 2-1.

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