San Francisco Giants vs. Baltimore Orioles, Picks and Prediction, Saturday, April 11, 2026
Use Code WWWC San Francisco (5-8) will be trying to pick up their second consecutive series win when they visit Oriole Park at Camden Yards on Saturday night to face Baltimore (6-6) in the second game of their three-game interleague series at 7:15 PM. ET. Read on to find out which team picks up the win in this Giants vs. Orioles prediction. When it comes to MLB picks, our MLB Predictions are stellar.
Logan Webb, 1-1, 5.00 ERA, will get the start for the Giants. The Orioles will counter with Chris Bassitt, 0- 2, 14.21 ERA.
San Francisco is 6-4 in its last 10 games against Baltimore.
**This preview was written before Friday’s game was played.**
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Giants Trying To Stay Hot On The Road
The Giants bounced back from their series loss to the Mets with a series win over the Phillies. They won their first road series and will try to pick up their second straight win when they play the Orioles.
San Francisco averages 3.15 runs per game, which is 28th in the league. Their .233 batting average is 13th in the league. Their .283 on base percentage is 29th, while their .335 slugging percentage is 27th.
Luis Arraez leads the Giants with a .320 batting average. Rafael Devers leads the team with two home runs, while Matt Chapman leads the team with seven RBI.
San Francisco is giving up 4.38 runs per game, which is 17th in the league. Opponents have a .242 batting average against the Giants, which is 18th in the league. Their 4.03 ERA is 19th, while their 1..34 WHIP is 17th.
In his last start, Webb gave up seven hits and one run in seven innings, but the team lost a 5-2 game to the Mets. He is 0-1 with a 4.63 ERA in two starts against Baltimore.
Orioles Trying To Avoid Consecutive Home Series Losses
The Orioles bounced back from their series loss to the Pirates with a three-game sweep of the White Sox. They lost their last home series and will try to avoid losing consecutive series at home when they face the Giants.
Baltimore averages 3.75 runs per game, which is 20th in the league. Their .242 batting average is 11th in the league. Their .330 on base percentage is seventh, while their .362 slugging percentage is 15th.
Taylor Ward leads Baltimore with a .383 batting average, while Gunnar Henderson leads the team with four home runs and nine RBI.
Baltimore is giving up 4.08 runs per game, which is 14th in the league. Opponents have a .239 batting average against the Orioles, which is 16th in the league. Their 4.02 ERA is 18th, while their 1.39 WHIP is 22nd.
In his last start, Bassitt gave up six hits and six runs in two innings, leading to an 8-2 loss to Pittsburgh. He is 4-2 with a 3.91 ERA in eight games against the Giants.
Giants vs. Orioles Picks
Money Line Pick for Giants vs. Orioles
- San Francisco Giants ML (4 Units)
The Giants have the edge in this game because they’re playing well offensively, averaging five runs per game in their last three games. Even though they haven’t been great against right-handers, they’re going up against Bassitt, who hasn’t looked good on the mound so far, giving up 10 runs in two starts, failing to get past the fourth inning in both games. With Baltimore’s bullpen also struggling, expect the Giants to have their way offensively in this game.
Baltimore will have a hard time keeping up with San Francisco because they haven’t been as good offensively and scored 10 runs in their last three home games. Even though Webb struggled on the mound in his first start of the season, he did a better job in his last two starts, giving up four total runs, so expect him to keep Baltimore’s offense in check. Take San Francisco on the money line.
Over/Under Pick for Giants vs. Orioles
- Over (4 Units)
The Giants average 3.15 runs per game and averaged five runs per game in their last three games. They’re batting .207 against right-handers, and they’re facing a starter who gave up 10 runs in his first two starts. The Orioles average 3.75 runs per game. They’re batting .240 against right-handers, and they’re facing a starter who gave up 11 runs in three starts. Expect these teams to score enough runs to push the score over the total. The Giants and Orioles played over the total in their last seven meetings.
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