San Francisco Giants vs. Chicago Cubs, Picks and Prediction, Sunday, June 7, 2026

By: Bosun Akinpelu Published 06/07/2026, 05:00 AM ET
Giants vs. Cubs prediction
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San Francisco (26-38) will be trying to move up the NL West standings when they visit Wrigley Field on Sunday night to face Chicago (33-31) at 8:30 PM. ET. Read on to find out which team picks up the win in this Giants vs. Cubs prediction. Don’t go down on strikes! Get our top MLB Predictions and increase your bankroll!

Trevor McDonald, 2-3, 4.50 ERA, will get the start for the Giants. The Cubs will counter with Jameson Taillon, 2-5, 5.13 ERA.

San Francisco is 8-2 in its last 10 games against Chicago.

**This preview was written before Saturday’s game was played.**

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Giants Going For Fourth Win In Six Games

The Giants followed up their two-game losing streak with two straight wins, giving them their third win in their last five contests. They are facing a team they have dominated in recent years and will try to keep the momentum going with another win on Sunday.

San Francisco averages 3.96 runs per game, which is 26th in the league. Their .256 batting average is fourth in the league. Their .304 on base percentage is 27th, while their .408 slugging percentage is seventh.

Luis Arraez leads the Giants with a .325 batting average, while Casey Schmitt leads the team with 13 home runs and 35 RBI.

San Francisco is giving up 4.97 runs per game, which is 27th in the league. Opponents have a .253 batting average against the Giants, which is 24th in the league. Their 4.58 ERA is 23rd, while their 1.41 WHIP is 25th.

In his last start, McDonald gave up five hits and three runs in five innings, leading to an 8-3 loss to Milwaukee.

Cubs Trying To Snap Two-Series Losing Streak

The Cubs followed up their series split with Pittsburgh with two straight series losses. They have dropped to fourth in the NL Central standings, half a game behind third-placed St. Louis. They will try to turn things around and move up the division standings with a win on Sunday.

Chicago averages 4.70 runs per game, which is eighth in the league. Their .240 batting average is 18th in the league. Their .333 on base percentage is fifth, while their .391 slugging percentage is 15th.

Alex Bregman leads the Cubs with a .255 batting average. Ian Happ leads the team with 14 home runs, while Michael Busch leads the team with 36 RBI.

Chicago is giving up 4.41 runs per game, which is 15th in the league. Opponents have a .238 batting average against the Cubs, which is 13th in the league. Their 4.17 ERA is 18th, while their 1.23 WHIP is seventh.

In his last start, Taillon gave up six hits and two runs in 6.1 innings, leading to a 2-1 loss to the Athletics. He is 1-1 with a 6.88 ERA in four games against the Giants.

Giants vs. Cubs Picks

Money Line Pick for Giants vs. Cubs

  • San Francisco Giants ML (4 Units)

The Giants have the edge here because they played well offensively in recent games, scoring 16 runs in their last three games. They’ve had a lot of success against right-handers, and they’ve also had a lot of success against Taillon, who gave up 18 runs in his last four starts, so expect them to play well offensively in this game.

The Cubs will have a hard time keeping up offensively because they aren’t playing as well as the Giants and scored more than four runs once in their last four games. They’ve also struggled against right-handers, and they’re facing McDonald, who has done well on the mound in recent starts, giving up seven runs in his last three road starts, so expect him to keep their offense in check, Take San Francisco on the money line.

Over/Under Pick for Giants vs. Cubs

  • Over (4 Units)

The Giants average 3.96 runs per game. They’re batting .259 against right-handers, and they’re facing a starter who gave up 18 runs in his last four starts. The Cubs average 4.70 runs per game. They’re batting .236 against right-handers, and they’re facing a starter who gave up 13 runs in his last three starts. Expect these teams to score enough runs to push the score over the total.

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