San Francisco Giants vs Los Angeles Dodgers Picks and Predictions for Sunday, September 20th, 2026

The San Francisco Giants continue their brief road trip Sunday afternoon, facing the Los Angeles Dodgers at 4:10 PM at Dodger Stadium, and we have you ready to roll with our San Francisco vs. Los Angeles prediction. This season, the Giants are nearly 30 games below .500, making them the second-worst team in the National League West. In contrast, the Dodgers are more than 30 games above .500 as they head into Sunday, leading the National League West and having already secured the division title. Read more about this San Francisco vs. Los Angeles prediction! Struggling with handicapping? Try our MLB Predictions!

 Giants look to end the year

Offensively, San Francisco has a .248 batting average this season, scoring 651 runs on 1,293 hits. The Giants have a .309 on-base percentage and a .407 team slugging percentage. San Francisco’s pitching staff has struggled throughout the year, posting a 4.37 team ERA. Jung Hoo Lee leads the Giants with a .274 batting average and 146 hits, while Rafael Devers has supplied the power with 37 home runs and 98 RBIs.

Yunior Marte started for the San Francisco Giants on Saturday and took the loss after allowing 6 runs on 8 hits over 4.2 innings. The Giants' bullpen struggled as well, giving up 4 runs—only 1 earned—on 7 hits in the last 3.1 innings of the game. Victor Bericoto led the San Francisco offense with 2 hits, including a home run, along with 2 RBIs and 2 runs scored. Jung Hoo Lee contributed with 2 hits and 1 RBI, while Jonah Cox drove in the Giants’ other run.

Key Injury Report for San Francisco:

• JT Brubaker RP 15-Day IL
• Matt Gage RP    60-Day IL
• Bryce Eldridge DH Day-To-Day
• Marcelo Mayer 2B 10-Day IL
• Willy Adames SS 10-Day IL

Dodgers try to keep it rolling

The Los Angeles offense has been one of the strongest in baseball this season, batting .256 with 767 runs scored on 1,323 hits. The Dodgers have recorded a .338 on-base percentage and a .424 team slugging percentage. Los Angeles has also pitched well, carrying a 3.63 team ERA. Freddie Freeman leads the Dodgers with a .290 batting average and 161 hits, while Shohei Ohtani has a team-high 30 home runs and 80 RBIs.

Tarik Skubal started on the mound and secured the win for Los Angeles on Saturday, despite allowing 4 runs on 8 hits over 5 innings. The Dodgers' bullpen was impressive, shutting out San Francisco without a hit or a run in the final 4 innings. Mookie Betts led the Los Angeles offense with 4 hits, 2 RBIs, and 2 runs scored. Will Smith contributed with 3 hits, including a home run, and also drove in 2 runs. Additionally, both Josue De Paula and Tommy Edman drove in 2 runs each.

Key Injury Report for Los Angeles:

• Gavin Stone SP  60-Day IL
• Jake Cousins RP 60-Day IL
• Dalton Rushing C       10-Day IL
• Andy Pages CF  10-Day IL
• Ben Casparius RP       60-Day IL

San Francisco vs Los Angeles Pick

• San Francisco vs Los Angeles Spread Pick

The Los Angeles Dodgers are the stronger team in this matchup, while the San Francisco Giants have nothing left to fight for. Expect the Dodgers to maintain their momentum as their offense takes charge on Sunday. I predict Los Angeles will close out the series with a home win against a struggling San Francisco team.

• San Francisco vs Los Angeles Over/Under Pick

The Los Angeles offense has been fantastic lately and will continue Saturday. Look for Los Angeles to keep running it up in this game as they fine-tune their offense heading into the postseason. Though the Giants offense has been down this year, they will likely get multiple chances to score, as the Dodgers will likely rely on their bullpen Sunday, since they still haven't announced a starter. Expect runs and bunches to come as the Los Angeles Dodgers do the work at home to get another victory against San Francisco.