Seattle Mariners vs. Chicago White Sox Picks and Prediction for Saturday, May 9th, 2026

By: Adam Rauzino Published 05/09/2026, 04:50 AM ET
Cubs vs White Sox prediction
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The Seattle Mariners (18-20, 12-26 RL, 17-20-1 O/U) meet the Chicago White Sox (17-20, 21-16 RL, 20-17 O/U) in game two of a three-game series on Saturday afternoon in the South Side of Chicago. The Mariners are sending Luis Castillo to the mound. The White Sox will counter with Anthony Kay. The Mariners went 5-1 against the White Sox last season.

Can Castillo and the Mariners come away with a road win on Saturday? Check out the Mariners vs. White Sox prediction. Do you need a boost in your handicapping? Try our MLB Picks!

Castillo Targets First Win of Season

Luis Castillo will be on the rubber on Saturday. Castillo had some difficulty again in his previous effort, squandering four runs on six hits in six innings against K.C., and was hit with another loss. The veteran has hit a bump, giving up 11 runs in his last two starts, which has inflated his ERA to 6.29, and a 1.66 ERA along with an 0-3 record in 34.1 innings pitched on the season. Castillo has thrived in his career against Chicago, as seen in his 1.71 ERA and a 2-0 record in 26.1 innings.

The Seattle Mariners are inching closer to the .500 mark. It’s been a subpar season, but they are only a few games out of first in the division. The Mariners were swept by K.C. last weekend and earned two wins in three home clashes against a hot Braves team this week, led by the pitching. Seattle netted 10 runs and kept the Braves to eight runs. The Mariners stand at 6-9 on the road.

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Julio Rodriguez is swinging a hot bat, clubbing three home runs with five RBIs in May. The 25-year-old slugger has five big flies with 17 RBIs and a .730 OPS on the season. Cal Raleigh is hitting an abysmal .175, but the power has been on display, bashing seven home runs with 18 RBIs. Josh Naylor is familiar with the White Sox due to his time in Cleveland. The first baseman has 17 RBIs. He posted a stellar 1.7 OPS against the White Sox last season.

Randy Arozarena has been kept in check, managing only one RBI this month. The veteran slugger has delivered 12 RBIs and a .766 OPS. Cole Young has been outstanding. The rookie has driven in 20 runs. J.P. Crawford has two home runs in his past three games. Crawford has 11 RBIs and a .720 OPS on the season.

Seattle is posting an average of 4.05 runs per game, ranking them 23rd. The Mariners have reported a strong 3.63 ERA, placing them sixth.

Anthony Kay Gets the Nod

The Sox are going with Anthony Kay in this one. Kay worked out of danger in his previous outing, conceding three runs (two earned) on seven hits in five innings of work against San Diego, and finished with a no-decision in a game the White Sox lost. The veteran southpaw was strong early in the season but has been shaky since and now owns a 5.70 ERA and a 1.70 WHIP, accompanied by a 1-1 record in 30 innings. Kay has netted 20 strikeouts. Kay has tossed four shutout innings in his career against the Mariners.

The Chicago White Sox are not contenders, but there have been plenty of positives. They went 3-3 on a six-game road trip, which concluded earlier this week. This included a series win against the Padres. Next, the White Sox were hit with two defeats in three meetings against the Angels. The bats delivered 11 runs while the pitching staff surrendered 12 runs. The White Sox are 7-8 at home.

Colson Montgomery is a promising young hitter to keep an eye on. The 24-year-old shortstop has compelling numbers, clubbing nine homers with 23 RBIs. Montgomery recorded one RBI against the Mariners last season. Miguel Vargas usually bats in the top half of the order. The 26-year-old third baseman has solid numbers, slugging seven bombs with 18 RBIs.

Chase Meidroth is another young hitter with potential. The second baseman only has five RBIs but a decent .729 OPS. Munetaka Murakami has been a beast at the plate. The 26-year-old was a star in Japan, and it has led to success in Chicago, posting 28 RBIs along with a .930 OPS. Sam Antoncci is one of Chicago's top prospects. The 22-year-old has been solid, issuing eight RBIs and a .788 OPS in 20 games.

Chicago is scoring an average of 4.19 runs per game, rating them 20th. The pitching staff has yielded a 4.23 ERA, placing them 19th in the big leagues.

Mariners vs. White Sox Pick

Spread Pick for Mariners vs. White Sox

  • Seattle Mariners -135 (5 units)

The Seattle Mariners have been a big threat on the road, where they have won two straight series. They also secured a series win against the Braves this week. The Chicago White Sox are a younger group and just dropped two of three games against a bad Angels squad.

Furthermore, Mariners pitcher Luis Castillo has silenced the White Sox in his career, producing a minuscule 1.71 ERA in a decent sample size of 26.1 innings. White Sox pitcher Anthony Kay has not enjoyed any success in his big league career, and that has continued this season. Kay has reported an abysmal 5.62 ERA and has given up at least four runs in two of his past three outings. He is also not pitching deep into games, going five or fewer innings in all but one start. Go with the Mariners.

Over/Under Pick for Mariners vs. White Sox

  • Under 8.5 (5 units)

I expect this one to go under. Seattle has not been able to break out at the plate this season. They have scored three or fewer runs in four of their past five games entering Friday. The White Sox' pitching is keeping them in games, yielding two or fewer runs in five of their past eight games.

In addition, Castillo has conceded two or fewer runs in two of his three road outings this season. He tossed seven shutout innings against Chicago in the only meeting last season. Also, Chicago has been kept in check. They have been held to only 18 runs in their past five games. The under is a convincing 7-3 in the White Sox's past 10 games.

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