Seattle Mariners vs. Kansas City Royals, Picks and Prediction, Thursday, September 18, 2025

By: Bosun Akinpelu Published 09/18/2025, 02:47 AM ET
Mariners vs. Royals prediction
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Seattle (83-68) will be going for the series win when they visit Kauffman Stadium on Thursday afternoon to face Kansas City (75-76) in the final game of their three-game series at 2:10 PM. ET. Read on to find out which team picks up the win in this Mariners vs. Royals prediction. Don’t go down on strikes! Get our top MLB Betting Picks and increase your bankroll!

Luis Castillo, 9-8, 3.76 ERA, will get the start for the Mariners. The Royals will counter with Stephen Kolek, 5-5, 3.71 ERA.

Kansas City and Seattle split their last 10 meetings.

**This preview was written before Wednesday’s game was played.**

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Seattle Trying To Increase Division Lead

The Mariners played well over the past week, and they’ve won 10 of their last 11 games. They have retaken the AL West lead, with a half-game lead over Houston. They will try to keep the momentum going and increase their division lead with a win on Thursday.

Seattle averages 4.75 runs per game, which is 10th in the league. Their .244 batting average is 18th in the league. Their .321 on base percentage is 11th, as is their .419 slugging percentage.

Julio Rodriguez leads Seattle with a .271 batting average, while Cal Raleigh leads the team with 56 home runs and 118 RBI.

Seattle is giving up 4.36 runs per game, which is 16th in the league. Opponents have a .243 batting average against the Mariners, which is 14th in the league. Their 3.92 ERA is 13th, while their 1.24 WHIP is eighth.

In his last start, Castillo gave up three hits and one run in six innings, leading to a 2-1 win over the Angels. He is 2-2 with a 3.98 ERA in seven games against Kansas City.

Kansas City Trying To End Slump

The Royals didn’t play well over the past week, and they’ve lost four of their last five games. They are sixth in the AL wildcard standings, seven games out of the final wildcard spot, and will try to make up some ground with a win on Thursday.

Kansas City averages 3.85 runs per game, which is 28th in the league. Their .244 batting average is 19th in the league. Their .305 on base percentage is 25th, while their .390 slugging percentage is 20th.

Bobby Witt Jr. leads Kansas City with a .292 batting average, while Vinnie Pasquantino leads the team with 30 home runs and 104 RBI.

Kansas City is giving up 3.98 runs per game, which is fourth in the league. Opponents have a .243 batting average against the Royals, which is 15th in the league. Their 3.78 ERA is fifth, while their 1.26 WHIP is 13th.

In his last start, Kolek gave up three hits and one run in 6.2 innings, leading to a 3-2 loss to Cleveland.

Mariners vs. Royals Pick

Money Line Pick for Mariners vs. Royals

  • Kansas City Royals ML (4 Units)

The Royals have won three of their last five home games, while the Mariners have lost four of their last seven road games. Kansas City has the edge here because they’ve hit the ball well against right-handers, and they’re going up against Castillo, who struggled on the mound in recent road starts, giving up nine runs in his last three road starts. He gave up nine runs in his last three starts against the Royals and will have a hard time slowing them down.

Seattle won't be as successful offensively because they haven’t hit the ball as well as the Royals, and they’re going up against Kolek, who did a good job on the mound in recent starts, giving up four runs in his last three starts. He gave up three runs in his last two home starts, and won't have trouble keeping Seattle’s offense in check. Take Kansas City on the money line.

Over/Under Pick for Mariners vs. Royals

  • Over (4 Units)

The Mariners played over the total in three of their last four games, while the Royals played over the total in their last three games. Seattle averages 4.75 runs per game and averaged 9.33 runs per game in their last three games. They’re batting .246 against right-handers, and they’re facing a starter who gave up nine runs in his last three home starts. The Royals average 3.85 runs per game and averaged seven runs per game in their last three games. They’re batting .247 against right-handers, and they’re facing a starter who gave up nine runs in his last three road starts. Expect these teams to score enough runs to push the score over the total. The Mariners and Royals played over the total in six of their last eight meetings.

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