St. Louis Cardinals vs. Athletics Picks and Prediction for Tuesday, September 2, 2025
It’s an intraleague battle in the MLB on Tuesday, Sept. 2. Read our Athletics vs St. Louis Cardinals prediction along with the rest of the games on the slate around the league. The Athletics are 64-75 and the have won eight of their last 13 games. They need to go on an impressive final month run to give themselves a chance at the playoffs. The Cardinals are 68-71 and they have lost six of their last 10 games as they are 6.5 games back of a wild card spot. The Athletics are set to start Luis Severino while Miles Mikolas gets the nod for the Cardinals. The first pitch is set for 7:45 P.M. EST.
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Athletics winners of 8 of last 13 games
The Athletics are 64-75 overall this season. They are in last place in the National League West division. They are 12.5 games back of the Astros for the division lead. They are 10 games back of a wild card spot with a month left to play. They are 35-35 when they have played on the road. The Athletics have won eight of their last 13 games coming into Tuesday. In their last game, the Athletics defeated St. Louis 11-3 on Monday, Sept. 1.
The Athletics are set to start Luis Severino in this game against the Cardinals. The right-handed pitcher is 6-11 with a 4.82 ERA in 24 starts. His last start saw him throw six innings against the Nationals on Aug. 5. He allowed three runs and five hits in a 16-7 win. The Athletics have won four straight games that Severino has made a start. The Athletics are 9-15 when Severino has started this season. He has an ERA of 6.34 in 13 starts this year on the road. They haver a 3.13 ERA in four starts since the All-Star break coming into this game. He has made seven starts against the National League with a 4.19 ERA.
The Athletics are hitting .254 this season which ranks fourth in the league. They have scored the 11th most runs while they rank third best in this. The Athletics have hit the second most doubles while they have also hit the fifth most home runs. They have struck out the eighth most times, too. They are hitting .245 when they have played on the road. They have a .262 batting average since the All-Star break while they also hit .262 in August. The Athletics have a .257 batting average against the National League.
Cardinals losers of 6 of last 10 games
St. Louis is 68-71 overall this season. They are in fourth place in the National League Central division. The Cardinals are 17.5 games back of the Brewers for first place. They are 6.5 games back of the Mets for the final wild card spot. They have lost six of their last 10 games coming into Tuesday. In their last game, the Cardinals lost 11-3 to the Athletics at home on Monday, Sept. 1.
On Tuesday, the Cardinals are set to start Miles Mikolas. The right-handed pitcher is 6-10 with a 5.04 ERA in 26 starts. Mikolas’ last start saw him throw five innings against the Pirates on Aug. 28. He allowed one run and four hits in a 4-1 win. The Cardinals are 12-14 when Mikolas has started this season. Mikolas has a 3.57 ERA in 13 starts at home. Since the All-Star break, Mikolas has a 5.30 ERA in eight starts. He has a 7.97 ERA in nine starts against the American League.
The Cardinals are hitting .247 this season which ranks 17th in the league. They rank 16th in runs scored and 17th in hits. St. Louis has hit the sixth fewest home runs, while they have also struck out the eighth fewest times. The Cardinals are hitting .252 at home and .235 since the All-Star break. St. Louis has a .237 batting average in August while they are also hitting .268 when facing American League teams.
Athletics -1.5
This is going to be a high scoring game between two teams that are most likely not going to make the playoffs. I am going to ride the hot hand with the Athletics, who have won eight of their last 13 games. They have also been surprisingly good on the road with their 35-35 record. The Cardinals have lost six of their last 10 and will make it another defeat in this game. Luis Severino gets the start and he’s been solid with an ERA of 3.13 since the All-Star break. The Athletics have won four straight games with him on the mound. The Cardinals are starting Miles Mikolas, who has not been good against American League teams. He has an ERA of 7.97 against AL teams this yer in seven starts. The Cardinals are also coming off of a month where they hit .237 from the plate.
Take the Athletics to cover.
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Over 8.5 runs
Offense should steal the show in this game with Miles Mikolas starting for the Cardinals. He has a 7.97 ERA against AL clubs while also holding a 5.30 ERA since the All-Star break. There will be plenty of chances for the Athletics with their .257 batting average against National League clubs. They are also hitting .262 in the second half of the season. The Cardinals should put some runs up, too. They have a .252 batting average at home and rank 16th in runs scored.
Take the over on Tuesday
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