St. Louis Cardinals vs Houston Astros Picks and Predictions for Sunday, April 19, 2026
Use Code WWWC The Saint Louis Cardinals stay on the road Sunday afternoon with a 2:10 PM match-up inside Daikin Park in Houston, Texas, against the Houston Astros, and we have you ready to roll with our St. Louis vs Houston prediction. Saint Louis comes into Sunday with 12 wins and 8 losses on the year. The Houston Astros stay at home for this matchup, struggling immensely with only 8 wins through 22 games played. Saint Louis is running hot on a 4-game winning streak after taking both games in this series thus far. Houston is struggling on a 3-game losing streak after the 2 losses in this series. Read more about this St. Louis vs Houston prediction! Struggling with handicapping? Try our MLB Predictions!
Cardinals look to keep it rolling
Offensively, St. Louis has a .233 team batting average, having scored 89 runs on 146 hits, and the Cardinals have scored 27 runs during their current 4-game winning streak. The Saint Louis pitching has been mediocre this season, with a 4.89 team ERA, and the Cardinals have allowed 17 total runs over their last four wins. The Cardinals’ offense has a .329 OBP and a .377 slugging percentage. Andre Pallante got the start and won for Saint Louis on Saturday, giving up one run on three hits across 5 innings of work. The Saint Louis bullpen was shaky, giving up 4 runs on only 1 hit over the final 4 innings of the win. Nolan Gorman and Masyn Winn led the way with the Saint Louis offense on Saturday, driving in 2 runs apiece.
Jordan Walker leads the Saint Louis offense this season with a .312 batting average, 8 home runs, and 16 RBI's. Alec Burleson has chipped in heavily for Saint Louis with a .299 batting average. JJ Wetherholt has a .236 batting average this season, and Nolan Gorman has boasted a .222 batting average but has played just 19 times.
Key Injury Report for St. Louis:
Get Free $30 Credit for Premium Picks + Exclusive Discounts
Subscribe Now
- Hunter Dobbins (15-Day IL)
- Matt Pushard (15-Day IL)
- Lars Nootbar (60Day IL)
- Ixan Henderson (60-Day IL)
- Victor Santos (60-Day IL)
Houston tries to end the issues
Offensively, Houston has been solid this season with a .262 batting average, and the Astros have scored 111 runs on 187 hits. Houston has a .353 OBP and a .434 team slugging percentage. The Houston pitching has been horrendous this season, with a 6.15 ERA and 19 runs allowed during its current three-game skid. Lance McCullers got the start and took the loss for Houston on Saturday, giving up 4 runs on 4 hits across 5 innings of action. The Houston bullpen struggled immensely, giving up 3 runs on 5 hits over the final 4 innings of the game. Shay Whitcomb provided the only real spark of the game for the Houston offense with 1 hit in 4 at-bats to drive in 3 runs.
Yordan Alvarez leads the Houston offense this season with a .342 batting average, 9 home runs, and 20 RBI's. Jose Altuve has a .278 batting average, and Christian Walker has a .263 batting average. Cam Smith has chipped in heavily with a .257 batting average this season across 22 games played.
Key Injury Report for Houston:
- Bennett Sousa (15-Day IL)
- Glenn Otto (Day-To-Day)
- Zach Dezenzo (10-Day IL)
- Jeremy Pena (10-Day IL)
- Tatsuya Imai (15-Day IL)
St. Louis vs Houston Pick
- St. Louis vs Houston Spread Pick
The Astros have had a ton of troubles thus far this season, and that will continue Sunday. Houston does have the better offense in this matchup, but they haven't played well lately. The Astros also have a terrible pitcher on the mound who will struggle against a good Saint Louis team. Look for Saint Louis to do the job on both sides of the dish as they get the win on the road in Houston Sunday against the Astros.
- St. Louis vs Houston Over/Under Pick
Both teams send out terrible pitchers on Sunday as each is struggling this season. Both pitchers have ballooned ERA's that will spark the opposing offenses in this matchup. Look for both teams to score in bunches as each pitcher continues their struggle in this matchup. Take the over Sunday as the Houston Astros host the Saint Louis Cardinals.
Never Tried Winners and Whiners? Now Is Your Chance
- Get your first daily picks package for ONLY $1 using coupon code DOLLAR
- If the pick loses, we credit your account with 3 Flex Picks
- If the pick wins, we still give you 1 Flex Pick on the house
- Win or lose, you walk away ahead. One dollar. No catch.
- Check out more MLB predictions
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days
