Toronto Blue Jays vs. Kansas City Royals Prediction, Sunday, September 21, 2025
Use Code WWWC In this Blue Jays at Royals prediction, the Blue Jays and Royals wrap up their weekend series in Kansas City on Sunday afternoon. The Blue Jays are trying to wrap up the AL East Division title with a week left in the season. The Royals are out of the playoff hunt, but can spoil the Blue Jays' chances at the AL East crown and the top record in the American League. The pitching matchup on Sunday will be Blue Jays’ righty Trey Yesavage (0-0, 1.80) taking on Royals’ right-hander Michael Wacha (9-12, 3.79). The first pitch is scheduled for 2:10 PM EST. Read on for more in this Blue Jays/Royals prediction, and grab our top MLB predictions to increase your bankroll!
Blue Jays closing in on AL East crown
The Toronto Blue Jays head into Saturday night’s matchup with the Royals holding a three-game lead over the Yankees in the AL East Division. They also have a four-game lead over the Tigers for the best record in the American League. The Blue Jays’ magic number to win the AL East is five after Friday night. Despite losing 20-1 to the Royals, the magic number dropped by one thanks to the Yankees’ loss to the Orioles. Blue Jays’ starter Max Scherzer was hammered for seven hits and seven runs in just .2 innings of work to take the loss on Friday night at KC.
*This article was written before the conclusion of Saturday night’s Blue Jays/Royals game.
The Blue Jays are in great shape to wrap up both the top seed and AL East crown this week if they can take care of business. On Sunday, they can inch closer to both goals with a win over the Royals. They will send youngster Trey Yesavage to the hill in the series finale. The 22-year-old will be making just his second career start on Sunday. In his first start, an eventual 2-1 Blue Jays’ win over the Rays in 11 innings, Yesavage was effective. He went five innings and allowed three hits and one run. The righty struck out nine to keep the Jays in the hunt before pulling out the win.
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Key Injuries: RP Angel Bastardo, RF Anthony Santander, RP Nick Sandlin, SP Bowden Francis, and SS Bo Bichette are out.
Royals bats boom against Jays
The Kansas City Royals will not be making back-to-back appearances in the American League playoffs after ending a 10-year playoff drought last season. They can still have an impact on the playoff picture, particularly this weekend against the visiting Jays. In game one, the Royals’ bats came alive, scoring seven runs in the first inning and never looking back in a 20-1 win. Sal Perez homered and drove in three runs while Jac Caglione went 2-for-5 with a home run, three runs scored, and knocked in four runs.
*This article was written before the conclusion of Saturday night’s Blue Jays/Royals game.
The Royals improved to 77-77 on the season with their game one victory on Friday night. They can further dampen the Blue Jays’ division title hopes with another win on Sunday. They’ll send veteran righty Michael Wacha to the mound on Sunday. Wacha is 9-12 on the season in 29 starts with 12 quality starts. He has allowed 156 hits in 161.2 innings of work. Wacha has an ERA of 3.79 and a WHIP of 1.22. He has walked 41 batters and struck out 117. The Royals have lost three of Wacha’s last five starts. He has a home record of 5-6 in 16 games with an ERA of 3.56.
Key Injuries: RP Lucas Erceg, RP Hunter Harvey, and CF Kyle Isbel are out.
Blue Jays at RoyalsÂ
Money line Pick for Blue Jays vs. RoyalsÂ
- Royals ML (4 units)
The Royals have played well against the Jays this season. They have won three of the first four meetings entering Saturday night’s game. They have also scored 36 runs in the three wins. They’ll send veteran Wacha to the hill on Sunday. Wacha is looking to record his 10th win of the season and sports a solid 3.36 ERA at home this season. Wacha also allowed just three hits and a run, picking up a win in his lone start against the Blue Jays earlier this season. The Blue Jays will counter with rookie Yesavage, making just his second career start. The Royals will have the benefit of being able to view tape on the youngster, which will give them an edge.
Take the Royals with the money line.
Over/Under Pick for Phillies at DiamondbacksÂ
- Over (4 units)
As noted, the Royals have piled on the runs in their three wins over the Jays, averaging over ten runs per game. The Royals have gone over the number in four of their last five games overall, including scoring 10 runs or more in three of those games. The Royals are playing loose and aggressively; expect those trends to continue on Sunday.
Take the Over.
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