Toronto Blue Jays vs. Minnesota Twins Picks and Prediction for Saturday, May 2, 2026
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It’s the continuation of a series on the diamond between a pair of American League teams hoping to find some positive momentum in the Twin Cities as the Toronto Blue Jays play the second game of a four-game set with the Minnesota Twins Saturday afternoon and we have you covered with our Blue Jays vs. Twins prediction. In the opening game of the set Thursday night, Minnesota picked up a 7-1 victory to draw first blood in the set. Will Toronto come up with a road victory or can Minnesota find a way to prevail at home? This article was published prior to the conclusion of the second game of the series at Target Field Friday night. Read more about this Blue Jays vs. Twins prediction! Winning isn’t easy so you need the top MLB picks.
Blue Jays Trying to Get to .500
Toronto had won four of their previous five games before getting smacked in the opening game of this series Thursday night. The Blue Jays entered Friday 14-17 on the year and stood fourth in the AL East, six games behind the Yankees for the top spot. In Thursday’s game against the Twins, Toronto finished with six hits as George Springer was the lone player with two. Daulton Varsho (his fourth) homered to account for the lone run for the Blue Jays in the contest. Kevin Gausman (2-2) took the loss as he allowed four runs on four hits with two walks and two strikeouts over 5.2 innings of work.
Dylan Cease is on the mound for the Blue Jays as he makes his seventh start of the year. He is 1-1 with a 2.87 ERA, a 1.372 WHIP, 17 walks and 49 strikeouts over 31.1 innings of work on the year. Cease took the loss in his last start, which came against the Red Sox at home Monday. He threw 5.2 innings, allowing four runs on seven hits with three walks and five strikeouts in a game the Blue Jays dropped 5-0. In his last three starts, Cease is 1-1 with a 3.24 ERA, a 1.32 WHIP, eight walks and 23 strikeouts over 16.2 innings of work. Cease makes his 14th career start against the Twins in this contest. He is 4-5 with a 4.69 ERA, a 1.31 WHIP, 33 walks and 79 strikeouts over 71 innings of work against them. Cease is 2-1 with a 3.09 ERA, a 0.90 WHIP, eight walks and 31 strikeouts over 23.1 innings in four career starts at Target Field. 
Minnesota Battling in AL Central Race
Minnesota had dropped two straight and seven of their previous eight games before taking the opener of the set Thursday night. The Twins entered Friday 14-18 on the year and stand fourth in the AL Central, two games behind Cleveland and Detroit for the top spot. On Thursday night, Minnesota finished with seven hits as Byron Buxton (two runs, RBI) had three hits and Ryan Jeffers (two runs, two RBI) added two in the game. Buxton (his eighth) and Jeffers (his fourth) each went deep in the contest. Bailey Ober (3-1) earned the win as he threw six innings, allowing one run on four hits with two walks and two strikeouts.
Connor Prielipp is on the hill as he makes his third start of the season for the Twins in this contest. He is 1-0 with a 4.00 ERA, a 0.889 WHIP, three walks and 11 strikeouts over nine innings of work. Prielipp earned the win in his last start, which came at home against the Mariners Monday night. He threw five innings, allowing two runs on one hit with three walks and five strikeouts in an 11-4 Twins victory. Prielipp, in his third career major league start, pitches against the Blue Jays for the first time here. This marks his second career start at Target Field. He is 1-0 with a 3.60 ERA, a 0.80 WHIP, three walks and five strikeouts over five innings of work there. Prior to being called up, Prielipp was 1-0 with a 2.30 ERA, a 1.213 WHIP, eight walks and 22 strikeouts over 15.2 innings in four appearances, three starts, at Triple-A St. Paul of the International League.
Blue Jays vs. Twins Pick
Moneyline Pick for Blue Jays vs. Twins
Toronto has won four of five and Minnesota had dropped seven of eight before Thursday’s contest. The Blue Jays are still struggling at the plate a month-plus into the season and have to get on track if they hope to contend this season. Cease is a front of the rotation pitcher with plenty of experience and electric stuff to boot. He had a rough outing against Boston his last time out but should bounce back. Prielipp earned his first big league win in his last start but he still is an unproven commodity at this stage. Look for Toronto to scratch out a victory in this contest.
Pick: Toronto Blue Jays (4 units)
Over/Under Pick for Blue Jays vs. Twins
Toronto has seen the over post a 16-15 mark on the year entering Friday night. The Blue Jays are 25th in the majors with 3.94 runs per game and that number drops down to 3.54 runs per game away from Rogers Centre. Toronto has an average total of 8.65 runs per game but that number falls to 8.08 runs per game at home. Minnesota entered Saturday with the over posting a 19-12 mark in their opening 31 games of the year. The Twins are 9th by averaging 4.81 runs per game, a number that bumps up to 5.24 runs per game at home. Minnesota has an average total of 9.47 runs per game on the season and that bumps slightly to 9.53 runs per game at Target Field. Cease turns in another solid outing, which keeps this under the number.
Under (4 units)
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