Toronto Blue Jays vs. Seattle Mariners Picks and Prediction for ALCS, Game 3, Wednesday, October 15, 2025
The World Series looms on the horizon and the postseason rolls on with a clash between a pair of squads looking to take another step toward that goal as the Toronto Blue Jays take on the Seattle Mariners in Game 3 of their best-of-seven AL Championship Series Wednesday night, and we have you covered with our Blue Jays vs. Mariners prediction. Seattle stole home-field advantage by taking Game 1 with a 3-1 road win Sunday night and followed that up with a 10-3 triumph in Game 2 Monday night for a 2-0 series advantage. Will the Blue Jays earn a win to get back in the series or will the Mariners move to the precipice of their first World Series appearance? Read more about this Blue Jays vs. Mariners prediction! Don’t go down on strikes! Increase your bankroll with our MLB Betting Picks!
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Blue Jays Trying to Get on the Board
Toronto, for all its success putting runs on the board against the Yankees, was stifled in the first two games of the ALCS, getting outscored 13-4 in falling into a 2-0 series hole. The Blue Jays are now on the road in need of a win to avoid falling into a 3-0 series hole. In Game 2 against Seattle, Toronto was down 3-0 before coming to the plate and never got even again as they went down in defeat. The Blue Jays finished the game with six hits as Nathan Lukes (run, RBI) led the way with three. Toronto went three of 10 with runners in scoring position and left seven runners on base in the contest. Trey Yesavage (1-1) took the loss as he allowed five runs on four hits with three walks and four strikeouts over four innings of work.
Shane Bieber takes the ball for his second postseason start of the year after making seven regular-season starts for the Blue Jays. He was 4-2 with a 3.57 ERA, a 1.017 WHIP, seven walks, and 37 strikeouts over 40.1 innings of work in the regular season. In the postseason, he has no record with a 6.75 ERA, a 2.25 WHIP, one walk, and two strikeouts. Bieber didn’t factor in the decision in his last start, which came against the Yankees on the road in Game 3 of the AL Division Series on October 7. He threw 2.2 innings, allowing three runs (two earned) on five hits with one walk and two strikeouts, in an eventual 9-6 Blue Jays loss. In his last three starts, Bieber is 1-1 with a 3.86 ERA, a 1.29 WHIP, four walks, and nine strikeouts over 14 innings of work. Bieber makes his eighth career start against the Mariners in this contest. He is 2-2 with a 2.30 ERA, a 1.209 WHIP, 10 walks, and 49 strikeouts over 43 innings of work against them. Bieber is 2-1 with a 1.52 ERA, a 1.112 WHIP, seven walks and 33 strikeouts over 29.2 innings in five career starts at T-Mobile Park.
Seattle Seeking 3-0 Series Advantage
Seattle shrugged off the fatigue factor of having to go 15 innings in Game 5 of their AL Division Series by taking both games north of the border against the Blue Jays. The Mariners now seek to prevail at home and take a 3-0 series lead. Against Toronto in Game 2, Seattle banged out 10 hits as Josh Naylor (run, two RBI) had three hits while Jorge Polanco (two runs, three RBI) added a pair in the game. Polanco (his third of the postseason), Julio Rodriguez (his second) and Naylor (his first) went deep in the win. Logan Gilbert threw three innings, allowing three runs (two earned) on five hits with one walk and two strikeouts, but didn’t factor in the decision. Eduard Bazardo (1-0) earned the win in relief as he threw two scoreless innings of relief, allowing one hits with no walks and one strikeout.
George Kirby is on the bump for the Mariners as he makes his third start of the postseason after logging 23 regular-season starts. He finished the regular season 10-8 with a 4.21 ERA, a 1.19 WHIP, 29 walks and 137 strikeouts over 126 innings of work. In the postseason, Kirby has no record with a 2.70 ERA, a 1.00 WHIP, one walk and 14 strikeouts over 10 innings of work. Kirby didn’t factor in the decision in his last start, which came at home against the Tigers in Game 5 of the AL Division Series on Friday. He threw five innings, allowing one run on three hits with no walks and six strikeouts in a game the Mariners won 3-2 in 15 innings. In his last three starts, Kirby is 0-1 with a 3.00 ERA, a 0.93 WHIP, two walks and 24 strikeouts over 15 innings of work. Kirby makes his fourth career start against the Blue Jays in this contest. He is 0-1 with a 6.28 ERA, a 1.884 WHIP, two walks, and 15 strikeouts over 14.1 innings of work against them. Kirby is 22-16 with a 3.07 ERA, a 1.043 WHIP, 47 walks and 330 strikeouts over 313.2 innings of work in 54 career starts at T-Mobile Park.
Blue Jays vs. Mariners Pick
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Tony Karpinski | +2,494.00 |
| 2 |  Joe Duffy | +1,859.00 |
| 3 |  The Insiders Room | +1,788.00 |
| 4 |  Mark Ruelle | +1,428.00 |
| 5 |  Jackie Mack | +1,400.00 |
Moneyline Pick for Blue Jays vs. Mariners
- Mariners -130 (4 units)
Toronto was a force to be reckoned with at Rogers Centre against the Yankees, but despite having everything in their favor, find themselves in a 2-0 hole heading to the Pacific Northwest. Seattle has had much better results from their pitching staff at T-Mobile Park at home as opposed to on the road, and Kirby is no exception in that department. He posted a 5.16 ERA on the road but recorded a 3.29 ERA at home over 76.1 innings of work this season. The Blue Jays weren’t as prolific offensively on the road as they were at home, and that could be a problem here. Bieber is still trying to get into form and struggled against the Yankees in his first postseason outing. With a world of momentum behind them, look for Seattle to come up with the win here.
Over/Under Pick for Blue Jays vs. Mariners
- Under 7 (4 units)
Toronto has seen the over post a 90-73-5 mark in their 168 games on the year entering Tuesday night. The Blue Jays are 3rd in the majors with 4.98 runs per game and that number falls to 4.55 runs per game away from Rogers Centre. Toronto has an average total of 9.46 runs per game but that number drops to 9.31 runs per game on the road. Seattle has seen the over go 92-71-6 in their first 169 games of the year entering Tuesday night. The Mariners are 10th in the majors with 4.72 runs per game, a number that falls to 4.29 runs per game on the road. They have an average total of 8.97 runs per game and that number drops to an even eight runs per game as the visiting team. With T-Mobile Park being a pitcher-friendly venue and temperatures ranging from the low-60s down into the mid-50s during the game, the ball likely doesn’t carry as it would in Toronto. Take the under here as a result.
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