Washington Nationals vs. Atlanta Braves Prediction and Picks - September 22, 2025

By: Dean Whitaker Published 09/22/2025, 07:30 AM ET
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Monday evening, Major League Baseball action, and we have a Washington Nationals vs. Atlanta Braves Prediction ready to rock and roll. Washington has been out of the race for a long time and comes in with a 63-92 mark. The Braves have been better down the stretch, as they have won eight games in a row, but are still going to miss the postseason this year. Read on to see our Nationals vs Braves prediction.

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Nationals Just Looking To Finish Strong

Washington snapped a four-game skid Sunday with a 3–2 win over the Mets, leaning on a sharp outing from Jake Irvin and timely hitting from Drew Millas, who drove in two with a bases-loaded single in the fifth. The bullpen held firm behind Jose A. Ferrer, who earned his 10th save, and the defense turned two double plays to preserve the lead. Notably, CJ Abrams was held out with a sore shoulder after a hard slide Saturday, leaving the top of the lineup a bit thinner. Still, the Nats showed resilience, and they’ll look to carry that energy into Atlanta.

Monday’s starter MacKenzie Gore (8–11, 4.32 ERA) has quietly been one of Washington’s most consistent arms. He’s posted a 2.89 ERA over his last four starts, including a one-hit gem against Miami last week. Gore’s strikeout rate (9.7 K/9) ranks among the top 15 in MLB, and he’s shown improved command with a 2.77 K/BB ratio. Against Atlanta, he’s allowed just one home run across 66 at-bats this season, and his ability to miss bats could be key against a lineup that’s been red-hot during their eight-game win streak. If Gore can get through six clean, Ferrer and Hunter Harvey have the late-inning stuff to keep it close.

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Offensively, the Nationals remain light on power but opportunistic. With Abrams potentially sidelined again, the pressure shifts to Dylan Crews, Joey Meneses, and Ildemaro Vargas to generate traffic. Crews has hit .284 since the break and continues to show advanced plate discipline, while Meneses has driven in 72 runs despite a dip in slugging. Washington ranks 26th in OPS and 27th in home runs, but they’ve hit the over in four of their last six games, often thanks to late rallies and aggressive baserunning. If Gore delivers and the bats stay patient, the Nats could make this one tighter than the odds suggest.

Braves Stay Hot With Eight Wins In A Row

Atlanta extended its win streak to eight games Sunday with a 6–2 win over Detroit, powered by Matt Olson’s 30th home run and a three-hit day from Drake Baldwin, who drove in two. Spencer Strider struck out nine over six innings, and the bullpen locked it down with clean frames from Pierce Johnson and Raisel Iglesias, who earned his 29th save. The Braves are surging late, averaging 6.0 runs per game during the streak and playing with renewed confidence and balance.

Monday’s starter Chris Sale (10–9, 3.77 ERA) gets a second straight crack at Washington after dominating them on September 16—eight scoreless innings with nine strikeouts. Sale has posted a 2.91 ERA at home, and his fastball-slider combo has generated a 34% whiff rate, making him a nightmare for a Nationals lineup that struggles against lefties. He’s walked just four batters in his last five starts, and with Iglesias rested and ready, Sale has the support to go deep and control the tempo again.

Offensively, Atlanta is firing on all cylinders. Nacho Alvarez Jr. is batting .318 over his last 12 games, and Jurickson Profar has driven in 14 runs this month. The Braves rank top 10 in slugging (.431) and home runs (204), and they’ve hit the over in six of their last nine games. If they can get traffic ahead of Olson and Baldwin, they’ll have chances to break it open early. With Sale on the hill and the lineup clicking, Atlanta enters Monday with momentum, matchup edges, and a chance to push the streak to nine.

Washington Nationals vs. Atlanta Braves Pick

Nationals vs Braves Moneyline Pick

  • Atlanta -1.5 (4 Units)

Atlanta -1.5 is a sharp play Monday night with Chris Sale on the mound and the Braves riding an eight-game win streak. Sale dominated Washington just six days ago—eight scoreless innings, nine strikeouts, and only three hits allowed—and he’s posted a 2.91 ERA at home this season. The Nationals counter with MacKenzie Gore, who’s shown flashes but faces a red-hot lineup that’s averaging 6.0 runs per game during the streak. Atlanta has covered the run line in five of its last six wins, and with Sale’s elite command and swing-and-miss stuff, they’re well-positioned to control the tempo early.

Offensively, the Braves are clicking from top to bottom. Matt Olson hit his 30th homer Sunday, Drake Baldwin added three hits and two RBIs, and Nacho Alvarez Jr. continues to rake with a .318 average over his last 12 games. Atlanta ranks top 10 in slugging (.431) and home runs (204), and they’ve consistently punished left-handed pitching. With Gore’s road ERA sitting above 4.50 and Washington’s bullpen converting just 64.7% of save chances, the Braves have multiple paths to separation. If Sale delivers his usual six-plus innings and the bats stay hot, Atlanta should cover -1.5 with room to spare.

Nationals vs Braves Over/Under Pick

  • Under 7 (5 Units)

Under 7 is a sharp lean in Monday’s Braves–Nationals matchup, with Chris Sale (2.35 ERA) and MacKenzie Gore (2.89 ERA over last four starts) both in strong form and facing lineups that have shown restraint in early innings. Sale blanked Washington over eight frames just last week, and Gore has allowed just one home run to Atlanta across 66 at-bats this season. The Nationals rank 27th in home runs and 21st in slugging, while Atlanta has leaned on timely hits rather than explosive innings during its win streak. With two high-strikeout lefties on the mound and both bullpens rested, this game profiles as a low-scoring grind with limited traffic and few crooked numbers.

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