Washington Nationals vs. Chicago Cubs, Picks and Prediction, Sunday, March 29, 2026
Use Code WWWC Washington (1-0) will be going for the series win when they visit Wrigley Field on Sunday afternoon to face Chicago (0-1) at 2:20 PM. ET. Read on to find out which team picks up the win in this Nationals vs. Cubs prediction. Don’t go down on strikes! Get our top MLB Predictions and increase your bankroll!
Jake Irvin will get the start for the Nationals. He was 9-13 with a 5.70 ERA last season. The Cubs will counter with Shota Imanaga, who was 9-8 with a 3.73 ERA last season.
Chicago and Washington split their last 10 meetings.
**This preview was written before Saturday’s game was played.**
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Nationals Going For Second Win In Three Games
The Nationals got their season off to a good start with a win over the Cubs in their opener. They will try to keep the momentum going and pick up their first series win of the season when they play on Sunday.
Washington scored 10 runs in their first game. They finished the game with a .297 batting average, a .350 on base percentage, and a .568 slugging percentage.
Joey Wiemer finished the game with a 1.00 batting average after going 3 for 3 in the game, while Jacob Young had a home run and two RBI.
Washington gave up four runs in the win. They will need a better performance from their pitching staff if they want to win this game.
In his last start, Irvin gave up six hits and four runs in six innings, leading to a 6-5 win over the White Sox. He is 0-4 with a 9.70 ERA in five games against the Cubs.
Cubs Looking For First Win
The Cubs couldn’t stop Washington’s offense in their first game and lost a game they were expected to win. They will try to bounce back from the loss and pick up their first win of the season when they play on Sunday.
Chicago scored four runs in their first game. They finished the game with a .235 batting average, a .350 on base percentage, and a .294 slugging percentage.
Michael Busch led the Cubs with a .750 batting average, while Pete Crow-Armstrong had two RBI.
Chicago gave up 10 runs in their first game. They will need a significantly better effort if they want to get the win.
In his last start, Imanaga gave up five hits and four runs in 2.2 innings, leading to a 7-3 loss to Milwaukee. He is 2-0 with a 2.08 ERA in two games against Washington.
Nationals vs. Cubs Picks
Run Line Pick for Nationals vs. Cubs
- Chicago Cubs -1.5 (4 Units)
The Cubs have the edge in this game because they hit the ball well against right-handers last season, and they’re going up against Irvin, who struggled on the mound last season, especially on the road, where he gave up 13 runs in his last three starts. He also struggled against the Cubs, giving up 10 runs in his last two starts against them. He gave up 12 runs in his last two starts at Wrigley, and will have a hard time slowing them down.
Even though they played well offensively in their first game, the Nationals will struggle on Sunday because they weren’t very good against left-handers, and they haven’t had a lot of success against Imanaga, who gave up three runs in two starts against them. Take Chicago to cover the run line.
Over/Under Pick for Nationals vs. Cubs
- Over (4 Units)
The Nationals averaged 4.24 runs per game last season. They had a .228 batting average against left-handers last season, and they’re going up against a starter who gave up three runs in two starts against them. The Cubs averaged 4.80 runs per game last season. They had a .249 batting average against right-handers, and they’re facing a starter who gave up 12 runs in his last two road starts against them. Expect these teams to score enough runs to push the score over the total. The Cubs and Nationals played over the total in three of their last four meetings.
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