Washington Nationals vs. Chicago Cubs Picks and Predictions for Thursday March 26, 2026

By: Garrett Beaverson Published 03/26/2026, 05:30 AM ET
Braves vs. Nationals Prediction
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We’ve got Opening Day baseball on March 26th in this Nationals vs. Cubs prediction, with the Washington Nationals taking on the Chicago Cubs at Wrigley Field. Get in on the action with our free MLB picks.

Nationals leaning on youth and upside

Washington enters the 2026 season in a developmental phase, but there’s legitimate optimism around their young core. While they struggled in 2025, the Nationals showed flashes offensively and now look to build consistency.

The centerpiece of the lineup is CJ Abrams, who took another step forward last season and enters 2026 as the team’s primary catalyst. Abrams brings speed, improving power, and the ability to create runs both on the bases and at the plate.

Outfielder James Wood is one of the most exciting young bats in baseball. After a strong finish last season, he’s expected to take on a major role in the middle of the lineup, providing power and run production.

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Brady House remains a steady presence, offering a steady bat, while Keibert Ruiz continues to develop as a contact-oriented catcher who can help stabilize the offense.

On the mound, the Nationals are expected to rely on a young rotation. Opening Day features Cade Cavalli in his first start since returning from Tommy John surgery.

Overall, Washington’s offense has upside, but consistency and pitching depth remain major concerns.

Strengths Young, athletic lineup with emerging power Speed and ability to create runs Upside from developing prospects

Weaknesses Inexperienced pitching staff Inconsistent offensive production Lack of proven high-end starters

Cubs built to compete in the NL Central

Chicago enters 2026 with legitimate expectations after a strong 2025 campaign. They bring back a balanced roster with a mix of veteran leadership and prime-age contributors.

The offense was led by Seiya Suzuki, but he will be sidelined to begin the season.

Dansby Swanson anchors the infield with steady production and elite defense, while Nico Hoerner adds contact hitting and speed at the top of the order.

One of the biggest advantages for Chicago is their starting pitching stability. Opening Day is expected to feature Matthew Boyd, who has emerged as a reliable front-line starter, reviving his career over the past two seasons.

Chicago also benefits from playing at home, where they’ve historically been strong.

Strengths Balanced, experienced lineup Strong starting pitching led by Steele Defensive consistency Home-field advantage

Weaknesses Can be streaky offensively at times Bullpen inconsistency in high-leverage spots Reliance on core veterans staying healthy

Nationals vs. Cubs Picks

Cubs -1.5 (5 units)

Opening Day can be unpredictable, but this is a clear talent mismatch.

The Cubs have the advantage in starting pitching, lineup depth, and experience, while the Nationals are still working through growing pains with a young roster.

Boyd should be steady and Chicago should put up runs.

Total Pick for Nationals vs. Cubs

Under 7.5 (5 units)

Opening Day games often trend lower scoring, particularly when one team features a strong starting pitcher.

Chicago’s pitching should limit Washington’s opportunities, while the Cubs themselves may take a few innings to get into rhythm early in the season.

Unless Washington’s young pitching completely unravels, this projects as a controlled, moderate-scoring game.

Projected Final Score

Cubs 5 Nationals 2

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