Washington Nationals vs Chicago White Sox Picks and Prediction for Sunday April 26 2026
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Major League Baseball action on Sunday afternoon, and we have a Washington Nationals vs Chicago White Sox prediction lined up and ready to roll. The White Sox took game one on Friday by a score of 5-4, and Washington bounced back yesterday with a 6-3 win. The Nats are just 3-6 in their last nine games and 12-16 on the year. Chicago has won 4 of its last 6, but it is still just 11-16 on the year. Read on to see our Nationals vs White Sox prediction.
Pitching Probables: The Nats will trot out Foster Griffin, who is 3-0 with a 3.38 ERA on the year. Chicago will counter with Bryan Hudson, who is 0-0 with a 1.54 ERA in 11.2 innings of work. He will be the opener in this one.
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Nationals Need More From Their Pitching
Washington enters Sunday with a chance to take the series after a steady 6–3 win that balanced out Friday’s one‑run loss. The Nationals remain 12–16 and have dropped six of their last nine, but their offense continues to outperform expectations. Washington ranks 3rd in MLB in runs per game (5.50) and sits 7th in OPS (.731), showing strong power and elite speed. They’ve already hit 33 home runs and stolen 29 bases, giving them multiple ways to pressure opponents. The problem has been pitching and defense, as the club carries a 5.44 ERA, 1.51 WHIP, and a league‑high 26 errors, which have repeatedly extended innings.
Washington hands the ball to Foster Griffin, who is 3–0 with a 3.38 ERA and has given the team a chance every time out. He has allowed only 10 earned runs in 26.2 innings, though the five home runs surrendered show the need for precision. The Nationals must support him with cleaner defense and early run production, especially against a Chicago staff that has struggled with traffic. If Washington keeps pressure on the bullpen and avoids the miscues that have hurt them all month, they can leave Chicago with a series win. 
The White Sox Have Won Four Of Six
Chicago looks to respond after Saturday’s loss, though the club has still won four of its last six and is showing signs of improvement. The White Sox sit at 11–16, and their offense has leaned heavily on power rather than consistent contact. Chicago ranks 21st in runs per game (4.15) and 27th in batting average (.226), but the 33 home runs place them 7th in MLB. They’ve struggled to sustain rallies, yet their ability to strike quickly keeps them competitive. The pitching staff owns a 4.83 ERA and 1.48 WHIP, but the strikeout rate sits at a strong 9.30 per game, giving them a chance to control innings when command holds.
Chicago turns to Bryan Hudson, who will open the game with a 1.54 ERA and 15 strikeouts in 11.2 innings. His job is to navigate the early matchups before the bullpen takes over, and Chicago needs stability behind him after allowing six runs on Saturday. The White Sox must limit Washington’s early bursts, protect the middle innings, and take advantage of scoring chances when they appear. If they keep the game tight and avoid defensive lapses, Chicago can push this series to a competitive finish.
Washington Nationals vs Chicago White Sox Pick
Nationals vs White Sox Spread Pick
- Washington +109 (4 Units)
Washington feels like the sharper side here, especially with Griffin giving them a reliable anchor in a matchup where Chicago’s offense still runs hot and cold. The Nationals have been inconsistent overall, but their lineup keeps producing, and that matters against a staff that allows plenty of traffic. Washington’s ability to score in multiple ways gives them a real edge when the game tightens, and Chicago’s opener‑heavy approach can create early cracks if Hudson isn’t sharp. With the Nationals carrying more momentum from Saturday’s win and matching up well against this pitching setup, Washington +109 has real value in a game that should stay competitive deep into the late innings.
Nationals vs White Sox Over/Under Pick
- Under 8.5 (5 Units)
The Under makes plenty of sense here because both lineups have leaned on power rather than steady traffic, and that usually drags the scoring pace down when neither side strings together long innings. Washington’s offense has been strong overall, but Chicago’s opener‑to‑bullpen setup can slow things early, and Griffin has been steady enough to keep the game from getting loose. Chicago’s contact issues also work in your favor, especially with their batting average sitting near the bottom of the league. If this one settles into a rhythm built around scattered baserunners and isolated scoring chances, Under 8.5 fits the matchup cleanly.
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