Washington Nationals vs. New York Mets Prediction and Picks - September 20, 2025

By: Dean Whitaker Published 09/20/2025, 07:00 AM ET
Pete Alonso looks to lead the Mets over the Nationals
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Friday evening Major League Baseball action, and we have a Washington Nationals vs New York Mets Prediction ready to rock and roll. The Nationals have had a rough season at 62-92, which puts them 29.5 games out of first in the National League East. New York can no longer win the NL East, but they are holding on to the 3rd wildcard spot in the National League. Still, their lead is just 2 games over Cincinnati. Can the Mets continue to hold on to that spot? Read on to see our Nationals vs Mets prediction.

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Nationals Continue To Struggle

The Nationals enter Saturday licking their wounds after a 12–6 loss to the Mets on Friday night, where they coughed up a 4–1 lead and committed three errors that led to six unearned runs. The bullpen was a disaster—Robert Garcia and Amos Willingham combined to allow five hits and four walks in just 1.2 innings—and the defense behind them collapsed. It was Washington’s sixth straight loss, and they’ve now allowed 27 runs over their last three games, with their team ERA ballooning to 5.33, second-worst in the majors. The Nationals have used 545 relievers this season, and their 64.7% save conversion rate reflects a unit that’s been overworked and underperforming.

Saturday’s starter Cade Cavalli (3–1, 4.76 ERA) has shown flashes of promise but remains inconsistent. He’s allowed 10.6 hits per nine innings, with a WHIP of 1.52, and has yet to pitch past the sixth inning in any start this season. Cavalli’s fastball has life, but his command has been spotty, and he’s struggled against lineups that hunt early counts—exactly what the Mets do best. He’ll need to be sharp to contain a red-hot New York offense that’s slugging .429 and ranks 4th in MLB in home runs. If Cavalli can’t get ahead in counts or induce weak contact, this could unravel quickly.

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Offensively, Washington has leaned heavily on CJ Abrams and rookie Dylan Crews, who combined for five hits and four RBI on Friday. Abrams launched a two-run homer and now leads the team with 17 home runs, while Crews continues to flash gap power and plate discipline. But beyond those two, the lineup lacks depth—ranking 25th in runs per game (4.2) and 27th in home runs (143). The Nationals have struck out 1,253 times and drawn just 425 walks, and their .306 OBP puts them in the bottom third of the league. If they’re going to hang with the Mets, they’ll need clean defense, timely hitting, and a quality start from Cavalli—none of which showed up Friday.

Mets Look To Strengthen Hold On Wildcard Slot

The Mets are surging at the right time, and Friday’s 12–6 win was a statement. After falling behind 4–1 early, they exploded for six runs in the fourth, led by Juan Soto’s 42nd home run, a career high, and Francisco Lindor’s three-hit, three-run night. Francisco Alvarez and Brandon Nimmo each drove in multiple runs, and the Mets finished with 13 hits and five walks, punishing every Nationals mistake. They’ve now scored 18 runs over their last two games, and their offense ranks 6th in slugging (.429) and 11th in total runs (722). With the Wild Card race tightening, New York is playing with urgency and confidence.

Saturday’s starter Nolan McLean (4–1, 1.19 ERA) has been one of the best rookie arms in baseball. He’s held opponents to a .194 batting average, struck out 40 in 37.2 innings, and posted four quality starts in his last six outings. McLean averages 6.2 innings per start and has held teams scoreless in three of his six appearances. His fastball-slider combo has been lethal, and he’s shown poise in high-leverage spots. With the bullpen fresh after using seven arms Friday, McLean should have full support behind him. If he continues to pound the zone and keep the ball in the park, the Mets are in prime position to sweep the series.

Defensively, the Mets have cleaned up their act. They’ve committed just one error over their last five games, and their .984 fielding percentage ranks 22nd but has trended upward in September. The infield has turned 125 double plays, and the outfield positioning has helped limit extra-base damage. With Pete Alonso anchoring first and Lindor flashing elite range at short, the Mets have tightened their fundamentals. Add in a lineup that’s drawn six or more walks in four of their last six games, and you’ve got a team that’s controlling tempo, grinding out at-bats, and playing playoff-caliber baseball.

Washington Nationals vs New York Mets Pick

Nationals vs Mets Spread Pick

  • NY Mets -1.5 (5 Units)

Mets -1.5 is a sharp run line play with both momentum and matchup support. New York is coming off a 12–6 win Friday night where they erased a 4–1 deficit and exploded for six runs in the fourth inning, capitalizing on three Nationals errors and a shaky bullpen. The Mets have now scored 18 runs over their last two games, and they’ve won 11 of 13 games (84.6%) when favored by at least -257 this season. Saturday’s starter Nolan McLean (4–1, 1.19 ERA) has been dominant, holding opponents to a .194 batting average and averaging 6.2 innings per start, with three scoreless outings in his last six. Backed by a lineup that ranks 4th in home runs and 6th in slugging, McLean is well-positioned to pitch deep and give the Mets a chance to cover comfortably.

On the flip side, Washington has dropped six straight and is just 3–7 ATS over its last 10 games. Starter Cade Cavalli owns a career 5.82 ERA and has allowed 10.6 hits per nine innings, facing a Mets offense that hunts fastballs and punishes early-count mistakes. The Nationals have allowed 27 runs over their last three games, and their bullpen has converted just 64.7% of save chances, with inherited runners scoring at a 40.2% clip. Defensively, they’ve committed 85 errors and rank near the bottom in double plays turned. With the Mets surging and the Nationals unraveling, laying the run and a half offers strong value in a game where New York’s firepower and pitching edge should create separation early.

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Nationals vs Mets Over/Under Pick

  • Over 8.5 (4 Units)

Over 8.5 is a strong play in Saturday’s Nationals–Mets matchup, with both teams trending toward high-scoring outcomes and the conditions ripe for another offensive surge. The Mets have hit the over in six of their last ten games, including Friday’s 12–6 explosion, and they’ve now scored 18 runs over their last two while ranking 4th in MLB in home runs (213) and 6th in slugging (.429). Washington’s pitching staff has been a liability, posting a 5.33 team ERA and allowing 842 runs on the season, while starter Cade Cavalli brings a career 5.82 ERA and a WHIP over 1.50 into a brutal matchup against a red-hot lineup. The Nationals have also hit the over in five of their last ten, and with defensive miscues and bullpen fatigue piling up, this game sets up for another crooked scoreboard.

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