Cavaliers at Pacers, , Picks, Odds, Preview, and Prediction, Monday, December 1, 2025

By: Liam Keating Published 12/01/2025, 10:43 AM ET
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It’s an Eastern Conference clash on Monday, Dec. 1. Read our Cleveland Cavaliers vs Indiana Pacers prediction along along with other NBA Picks. The Pacers are 4-16 and they are one of the worst teams in the East. Indiana has a 4-6 home record with every win this season coming inside their own building. The Pacers have won back-to-back games coming into this matchup. The Cavaliers are 12-9 and while they’ve been one of the East favorites, Cleveland has lost back-to-back games coming into this outing. These two teams will meet with tip-off set for 7 P.M. EST.

Cleveland struggling through three-game losing streak

Cleveland is 12-9 overall this season. The Cavaliers are in seventh place in the Eastern Conference. They are 4.5 games back of the Pistons for first place the conference. The Cavaliers are 4-5 when they have played on the road. They have lost three straight games while they have lost four of their last six games. The Cavaliers have lost their last two games when it has come in the second game of a back-to-back.

In their last game, Cleveland lost 117-115 to the Celtics at home on Sunday, Nov. 30. Boston led for the majority of the game as Cleveland could never find its footing. The Cavaliers never led in the second half as they played second-best. The Cavaliers shot 46% from the field and 38% from behind the 3-point line. The Cavaliers were out-rebounded in the loss. Evan Mobley led the team with 27 points on 11-for-17 shooting and 14 rebounds.

Donovan Mitchell leads the team with 30.6 points and 5.3 assists per game. Mobley is grabbing a team-high 8.9 rebounds per game.

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Cleveland ranks 15th in offensive efficiency and 10th in defensive efficiency. The Cavaliers are the 20th-ranked team in rebounding.

Cleveland is averaging 118.9 points per game, which ranks 12th in the league. They are the 21st-ranked shooting team, making 46% from the field. The Cavaliers are hitting 35.4% from behind the 3-point line, placing them 20th.

On defense, Cleveland is allowing 115.7 points per game, which ranks 14th. They are the 13th-ranked defense, allowing 46.6% from the field. Opponents are making 36.4% from behind the 3-point line, which ranks Cleveland 17th.

Cleveland is 6-15 against the spread this season. The Cavaliers are 3-6 against the spread when playing on the road. They are 2-5 against the spread as a road favorite. Cleveland is 1-3 against the spread with no rest and 2-6 against the spread after a loss. The under is 12-9 when the Cavaliers have played this season. The under is 12-9 when the Cavaliers have played this season. The over is 5-2 when Cleveland has been a road favorite. The total is 2-2 when the Cavaliers have had no rest.

Key injuries 

  • Jarrett Allen (finger), out 
  • Larry Nance Jr. (calf), out
  • Lonzo Ball (knee), questionable
  • Sam Merrill (hand), questionable 

Indiana winners of back-to-back games

Indiana is 4-16 overall this season. The Pacers are in third-to-last place in the Eastern Conference. Indiana has a 4-6 home record this season. After losing three straight games, the Pacers have won back-to-back games entering Monday night. The Pacers lost 120-109 to Cleveland in their only other meeting this year.

In their last game, the Pacers defeated Chicago 103-101 at home on Saturday, Nov. 29. Pascal Siakam nailed a 14-footer in the final second to win the game. Indiana shot 46% from the field and 32% from behind the 3-point line. The Pacers were led in scoring by Siakam with 24 points on 11-for-23 shooting. He also grabbed nine rebounds in the win. Isaiah Jackson secured a double-double off the bench with 14 points and 11 rebounds.

Pascal Siakam leads the team with 23.9 points and 7.2 rebounds per game. Andrew Nembhard is the top assistant with 6.2 per game.

Indiana is the second-worst-ranked offensive efficient team in the league. They are the 18th-ranked defensively efficient team, too. The Pacers rank 23rd in rebounding.

Indiana is averaging 109.8 points per game, which ranks second-worst in the league. They are the worst shooting team in the league, making 42.4% from the field and 31.7% from behind the 3-point line.

On defense, Indiana is allowing 118.6 points per game, which ranks 21st in the league. They are the 19th-ranked defensive team, allowing 47.2% from the field. The Pacers are forcing their opponents to shoot 32.1% from behind the arc, which ranks third best.

Indiana is 11-9 against the spread this season. They are 6-2 against the spread when they have been home underdogs. The Pacers are also 3-0 against the spread after a win. The under is 13-7 when the Pacers have played this year. The over is 5-3 as a home underdog. The under is 4-3 when the Pacers have a rest advantage.

Key injuries 

  • Kam Jones (back), out
  • Quenton Jackson (hamstring), out
  • Johnny Furphy (ankle), out
  • Aaron Nesmith (knee), out
  • Obi Toppin (foot), out
  • Tyrese Haliburton (Achilles), out

Cleveland Cavaliers vs Indiana Pacers Picks

Cavaliers vs Pacers Spread Pick

  • Indiana Pacers +5.5 (5 units)

The Cavaliers were one of the top teams entering the season. Many pundits had them at the top of the conference, but Cleveland is struggling with injuries. Right now, Cleveland is also out of form as they have lost three straight games, including a convincing loss to Boston on Sunday night. The Cavaliers have lost their last two games when they have come in the second game of a back-to-back. Indiana is playing their best basketball at the moment, too. The Pacers have won back-to-back games, including a big win over the Bulls. The Pacers have won all of their games at home this season. With the Cavaliers slipping and the Pacers finding form, Indiana should put together a strong performance at home. The Pacers are 3-0 against the spread after a win. The Cavaliers are 2-5 against the spread as a road favorite. Cleveland is 1-3 against the spread with no rest.

Take Indiana to cover.

Cavaliers vs Pacers Over/Under Pick

  • Over 233 (5 units)

The Cavaliers and the Pacers are two of the fastest teams in the league. The Cavaliers rank fifth in pace, while Indiana is the seventh-ranked pace team. The Pacers rank in the bottom half of defensive efficiency which will allow for some easy buckets for Cleveland. The over is 5-3 when Indiana has been a home underdog. The over is 5-2 for the Cavaliers when they have been a road favorite.

Take the over on Monday. 

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