Cleveland Cavaliers vs. Detroit Pistons, Picks and Prediction, Monday, October 27, 2025
Use Code WWWC The NBA season rolls on into the second week of the season on Monday, Oct. 27. Read our Cleveland Cavaliers vs Detroit Pistons prediction along with our other NBA Picks! The Cavaliers are 2-1 through the first couple of days of the season. They most recently defeated Milwaukee in their home opener on Sunday. The Pistons are 2-1, too. They are coming off a home win over the Celtics. These two teams will meet with tip-off set for 7 P.M. EST.
Cavaliers secure home-opening win vs Milwaukee
Cleveland is 2-1 overall through the first couple of games this season. The Cavaliers opened the season with a 119-11 loss to the Knicks on the road. They followed it with a 131-124 victory versus Brooklyn.
In their last game, the Cavs defeated Milwaukee 118-113 for their home opener on Sunday, Oct. 26. Cleveland led for the majority of the second half, but the Bucks kept battling back. The Bucks went on an 8-0 run to tie the game in the fourth quarter. But, Cleveland fired back with a 7-0 run that helped them retake the lead in the closing minutes. Cleveland would never give the lead up again despite a heroic performance from Giannis Antetokounmpo with 40 points on 14-for-20 shooting.
The Cavs countered with 24 points from Donovan Mitchell and 23 points from Evan Mobley in the win. Cleveland shot 44.8% from the field and 30% from behind the 3-point line in the win. They out-rebounded Milwaukee 44-37, which was key.
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Mitchell is averaging a team-high 30 points per game. He dropped 35 points on 10-for-15 shooting in the team’s win over Brooklyn a few days ago.
Cleveland is 0-3 against the spread through the first days. The Cavs have been favored in every game so far this season. The over is also 2-1 when they have played, too.
Cleveland is still missing their two starters in point guard Darius Garland and forward Max Strus. They are both set to miss this game against Detroit.
Detroit winners of back-to-back games
Detroit is 2-1 overall this season. The Pistons began their season with a 115-111 loss to the Bulls in their first game of the year. They bounced back with a 115-111 victory over Houston on the road, too.
In their last game, Detroit defeated Boston 119-113 at home on Sunday, Oct. 26. The victory sent Boston packing with an 0-3 record. Detroit grabbed the lead mid-way through the third quarter and they never let it go. The Pistons shot 42% from the field and 26.5% from behind the arc. The biggest difference was the rebounding as Detroit won the battle on the boards 55-38. Cade Cunningham led the team with 25 points on 8-for-18 shooting. Jalen Duren added 24 points, too.
Cunningham has been excellent through the first week. The fifth-year pro is averaging a team-high 23 points per game. His best game came against the Celtics as he was relentless, especially going to the free-throw line. He ended the game 7-for-7 from the stripe.
Detroit is 2-1 against the spread through the first three games. They have covered in back-to-back games as a 6.5 point underdog to Houston and as a 2.5 point favorite versus Boston. The under is 2-1 during Detroit games, too.
Jaden Ivey, Marcus Sasser, and Caris LeVert all missed Sunday’s game. Ivey will miss this game against Cleveland, while the other two players are questionable.
Cleveland Cavaliers vs Detroit Pistons Picks
Cavaliers vs Pistons Spread Pick
- Cleveland Cavaliers -2.5 (5 units)
It’s the first back-to-back for Cleveland and Detroit on Monday night. Through the first three games, both teams have an easy win, an impressive win and a poor loss. This game will be key to helping kick-start both teams ' season campaigns. The Cavaliers have shown different scoring options with the aggressiveness of Evan Mobley and the always reliable scoring threat Donovan Mitchell, despite key injuries to starters Darius Garland and Max Strus, Cleveland has looked solid.
The Pistons have played great team basketball with Cade Cunningham leading the way. With strong interior defense from Jarrett Allen and Mobley, Detroit will have a hard time generating easy baskets, especially as they lack a true No. 2 scorer behind Cade Cunningham. Starting guard Jaden Ivey remains sidelined. This will be a close game, but Cleveland’s multiple scoring options will be key in the second game of a back-to-back for both squads.
Take Cleveland to cover.
Cavaliers vs Pistons Over/Under Pick
- Under 231 (5 units)
Through the first three games of the season, Detroit and Cleveland are two of the fastest teams when it comes to pace. The Cavaliers rank sixth, while the Pistons are the ninth fastest team. But both teams do rank in the bottom half for offensive efficiency. Detroit ranks ninth right now in defensive efficienc,y while Cleveland has the defending defensive player of the year in Evan Mobley. Despite an expected frantic pace, defense will be key in this game.
Take the under on Monday.
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