Cleveland Cavaliers vs Detroit Pistons Picks and Predictions for Wednesday, May 13, 2026

By: Cameron Ross Updated 05/14/2026, 09:56 AM ET
Magic vs Cavaliers Prediction
Use Code WWWC

The Cleveland Cavaliers return to the road Wednesday night for Game 5 of the Eastern Conference semifinals inside Little Caesars Arena in Detroit, MI, at 8:00 PM against the Detroit Pistons, and we have you ready to roll with our Cleveland vs. Detroit prediction. Cleveland started this series shaky, but come into Wednesday running hot on a 2-game winning streak after winning Game 3 and Game 4 in Cleveland. The Detroit Pistons welcome home court Wednesday night, riding a 2-game skid after blowing a 2-0 series lead as their long winning streak ended in Cleveland. Read more about this Cleveland vs Detroit prediction! Struggling with handicapping? Try our NBA Predictions!

Cleveland hunts 3 in a row

Offensively, Cleveland has scored the ball well this season, averaging 119.5 points on 48% shooting from the floor. In this series, the Cleveland offense has been up and down, averaging 99 points in their 2 losses and 114 points in their 2 wins. Offensively, Cleveland was the better team in Game 4, pouring in 112 points, including 38 in the third quarter, on 44% shooting and 34% from beyond the arc. Cleveland pulled in 33 rebounds, including 12 on the offensive end. Donovan Mitchell scored 43 points on 26 shots to lead Cleveland in Game 4. James Harden added heavily to the Cleveland offense in Game 4 with 24 points on 14 shots in 37 minutes.

Donovan Mitchell is leading Cleveland in the playoffs, averaging 26.7 points per game. James Harden is second on the team, averaging 19.9 points, along with a team-leading 6.5 assists. Big man Evan Mobley is averaging 16.4 points and leads the team, pulling in 7.8 rebounds per game. Jarrett Allen is the 4th Cleveland player in double digits, averaging 11.9 points in just under 29 minutes per game.

Key Injury Report for Cleveland:

Get Free $30 Credit for Premium Picks + Exclusive Discounts

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Winners and Whiners may use third-party services to process my data.
  • None

Detroit looks to retake control of the series

The Detroit Pistons offense has carried the team this season, averaging 117.8 points on 49% shooting from the floor. Despite Detroit's strong offense, they have faltered in their last 2 losses, averaging just 106 points per game during their current 2-game losing streak. Offensively, Detroit was mediocre in game 4, scoring 103 points on 51% shooting and 43% from beyond the arc. Detroit won the rebounding battle by 2, but turned the ball over 20 times in the loss. Caris LeVert led the way for the Detroit offense with 24 points on 16 shots. Cade Cunningham added 19 points on 16 shots, while Tobias Harris chipped in 16 points on 17 shots in 36 minutes.

Cade Cunningham continues to lead the Detroit offense in the playoffs, averaging 29.2 points and 7.5 assists per game. Tobias Harris is second on the roster, averaging 20.8 points, and Duncan Robinson is averaging a third-best 11.5 points per game. Big man Jalen Duren averages 10.2 points and leads Detroit, pulling in 8.5 rebounds per contest. Ausar Thompson has been vital for the Pistons, averaging 8.5 points and 7.9 rebounds in just over 30 minutes per game.

Key Injury Report for Detroit:

  • Kevin Huerter (GTD) – Thigh

Cleveland vs Detroit Pick

  • Cleveland vs Detroit Spread Pick

Detroit started this series with a bang, going up 2-0 after the first 2 games in Detroit. Now, on Wednesday, this series returns to Detroit, tied at 2 games apiece after the Cavs held true at home. Look for Detroit to bounce back on Wednesday night and defend home court again. Take the Pistons to continue the series trend Wednesday night as the home team gets its fifth victory of this series. Take the Pistons on Wednesday night to get the win and cover at home, going up 3-2 in this series.

  • Cleveland vs Detroit Over/Under Pick

Both teams have been scoring the ball well, and that will continue in this matchup. The total has exceeded this number in each of the last 2 outings. Look for both offenses to continue rolling on Wednesday night, as they know how important Game 5 is. Take the over on Wednesday night as the Detroit Pistons retake control of this series with a win and cover at home.

Never Tried Winners and Whiners? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code DOLLAR
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
  • Check out more NBA predictions
BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Claim Bonus
Signup Promo Recommended BetMGM Sport Bonus
Min. Deposit $5
Cashable No
FanDuel Sportsbook

New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer FanDuel Sportsbook Bonus
Requirement New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days. (Up to $1,000 Bet Reset Tokens)
Cashable No
DraftKings Sport

New DraftKings Customers: Spend $5+ Get $200 in Bonuses Instantly!

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer DraftKings Sport Bonus
Min. Deposit $5
Odds Requirements -500
Cashable No

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright © 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.