Denver Nuggets vs. Houston Rockets, Picks and Prediction, Friday, November 21, 2025

By: Bosun Akinpelu Published 11/21/2025, 03:43 AM ET
Trail Blazers vs Rockets prediction
Use Code WWWC

Denver (11-3) will be going for their fifth consecutive road win when they visit Toyota Center on Friday night to face Houston (10-3) at 9:30 PM. Et. Read on to find out which team picks up the win in this Nuggets vs. Rockets prediction. No air balls here—only slam dunks with our NBA Picks!

The Nuggets are coming off a 125-118 win over New Orleans as 11.5-point favorites. The Rockets are coming off a 114-104 win over Cleveland as 1.5-point favorites.

Denver and Houston split their last 10 meetings.

Nuggets Going For Second Consecutive Win

The Nuggets bounced back from their loss to Chicago with a win over the Pelicans in their last game, giving them their fourth straight road win. They will try to keep the momentum going and pick up their second straight win when they play on Friday.

Get Free $30 Credit for Premium Picks + Exclusive Discounts

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Winners and Whiners may use third-party services to process my data.

Denver averages 124.6 points per game, which leads the league. They’ve made 51 percent of their field goals and 37 percent of their three-pointers.

Nikola Jokic leads Denver with 29.1 points, 13.2 rebounds, and 11.1 assists per game. Jamal Murray averages 22.5 points and 6.2 assists per game, while Aaron Gordon averages 20.3 points and 6.3 rebounds per game.

Denver is giving up 113.1 points per game, which is sixth in the league. Opponents have made 45 percent of their field goals and 31 percent of their three-pointers against them.

Key Injuries for Nuggets:

  • F Aaron Gordon (Hamstring) is questionable. Missed Wednesday's contest due to injury management.
  • G Christian Braun (Ankle) is out 6-7 weeks.

Rockets Going For Sixth Consecutive Win

The Rockets played well over the past week, and they come into this game on a five-game winning streak. They will try to keep the momentum going and pick up their sixth straight win when they play on Friday.

Houston averages 123.9 points per game, which is second in the league. They’ve made 49 percent of their field goals and 42.3 percent of their three-pointers.

Kevin Durant leads Houston with 25.5 points and 4.5 rebounds per game. Alperen Sengun averages 23.4 points, 10.4 rebounds, and 7.4 assists per game, while Amen Thompson averages 16.8 points, 6.3 rebounds, and 5.2 assists per game.

Houston is giving up 112.5 points per game, which is fifth in the league. Opponents have made 45 percent of their field goals and 36 percent of their three-pointers against them.

Key Injuries for Rockets:

  • F Dorian Finney-Smith (Ankle) is out
  • F Tari Eason (hip) is out 4-6 weeks. Averaged 11.5ppg, 5.2rpg

Nuggets vs. Rockets Picks

Point Spread Pick for Nuggets vs. Rockets

  • Houston Rockets -3.5 (4 Units)

The Rockets have won five straight games, while the Nuggets have won four of their last five games. Houston has the edge here because they’re playing well offensively, scoring more than 120 points per game while making 46 percent of their shots in their last three games. They also did a better job at the charity stripe, making over 85 percent of their free throws during that span. They rebound the ball well and grabbed more than 18 offensive rebounds per game in their last three games, which will give them more scoring chances. They also cut down their turnovers and won’t give up many easy-scoring chances. The Nuggets aren’t playing well defensively and gave up 120 points per game in their last three games, so expect them to have a hard time slowing down the Rockets. Go with Houston to cover the spread.

Over/Under Pick for Nuggets vs. Rockets

  • Over (4 Units)

The Nuggets played over the total in three of their last four games, while the Rockets played over the total in six of their last seven games. Denver averages 124.6 points per game. They play at the 21st-fastest pace in the league, averaging 103.8 possessions per game, and they’re facing a team that is giving up 111.2 points per game at home. The Rockets average 123.9 points per game. They play at the 25th-fastest pace in the league, averaging 103 possessions per game, and they’re facing a team that gave up 120 points per game in their last three games. Expect these teams to score enough points to push the score over the total. The Nuggets and Rockets played over the total in four of their last five meetings.

Never Tried Winners and Whiners? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code DOLLAR
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
  • Check out more NBA predictions
BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Claim Bonus
Signup Promo Recommended BetMGM Sport Bonus
Min. Deposit $5
Cashable No
FanDuel Sportsbook

New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer FanDuel Sportsbook Bonus
Requirement New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days. (Up to $1,000 Bet Reset Tokens)
Cashable No
DraftKings Sport

New DraftKings Customers: Spend $5+ Get $200 in Bonuses Instantly!

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer DraftKings Sport Bonus
Min. Deposit $5
Odds Requirements -500
Cashable No

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright © 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.