Denver Nuggets vs. Indiana Pacers Picks and Prediction for Wednesday, December 3rd, 2025
The Denver Nuggets (14-6, 12-8 ATS, 13-7 O/U) are on the road to take on the Indiana Pacers (4-17, 11-10 ATS, 8-13 O/U) in an inter-conference showdown on Wednesday evening, and we have you covered with the prediction. The Nuggets dropped a home meeting against the Mavericks on Monday. The Pacers were charged with a home defeat by the Cavaliers in their previous action. Denver issued a 117-110 home win against the Pacers in October.
Can the Pacers keep this one within 10 points on Wednesday? Check out the Nuggets vs. Pacers prediction. Do you need a boost in your handicapping? Try our NBA Picks!
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Denver Begins Road Trek on Wednesday
The Denver Nuggets are beginning a road trip in this game. Denver has won just two of its past five games. This includes a narrow 139-136 home defeat by the Spurs last week. They answered with a dominating 130-112 road win against the Suns on Saturday. The Nuggets were hit with a surprising 131-121 home defeat against the Mavericks on Monday in a clash that had the Nuggets marked as the 11-point favorites. They shot 47% and the Mavericks posted a 56% mark. The Nuggets are second in the division and 3rd in the conference. They have covered the spread in two of their past five games.
Nikola Jokic is having yet another outstanding season. The 30-year-old star center reached 30 points in six games last month. He scored 29 points in the win on Monday and has delivered an average of 29 PPG and 12.8 RPG. He dropped 32 against the Pacers last month. Jamaal Murray is in a groove, sinking 23 or more in four of his past five games. The veteran guard has netted an average of 23.3 PPG and 6.6 APG. Tim Hardaway Jr. amassed 13 points on Monday. The 33-year-old guard has been inconsistent at times and has posted 12 PPG on 45% shooting on the season.
Cameron Johnson has been a threat, amassing 15 or more points in four of his past five clashes. The 29-year-old forward is averaging 11.2 PPG on 46% shooting. The Nuggets are dealing with some injuries as Aaron Gordon and Christian Braun are out.
Denver is just as potent on the road, where it has won five straight games. This includes a win against the Timberwolves and Rockets. They covered in three games in that span. Denver has scored 120 or more in five straight games and is averaging 124.6 points on the season, leading the entire NBA. The Nuggets are conceding an average of 115.9 points, placing them 15th.
Indiana Wraps Home Stand on Wednesday
The Indiana Pacers are concluding a homestand in this one. Indiana has been a lot better in the past week or so. The squad has won two of its past three games. They snapped the long losing streak with a home win against the Wizards last week. The Pacers followed with a 103-101 home win against the Bulls on Saturday. They were competitive in a 135-119 home defeat by the Cavaliers on Monday in a clash that had the Pacers tabbed as five-point dogs. Indiana connected on 48% of its shots while Cleveland posted a 50% mark. The Pacers are last in the division. The Pacers have covered the spread in five of their past six games.
Pascal Siakam has been steady. The 31-year-old forward has shot above 50% in five of his last six games. He scored 26 points in the defeat on Monday. Siakam is sporting an average of 24.1 PPG on 47% shooting. Benedict Mathurin has been kept to 19 or fewer points in four of his past five games. The 23-year-old guard sank 11 points on Monday and is averaging 21.1 PPG on the year. Andrew Nembhard has surpassed 20 points in two of his previous five games. The 25-year-old has recorded an average of 17.5 PPG and 6 APG. He had one of his best games against the Nuggets, scoring 22 points.
The Pacers have injuries to key players. Obi Toppin is out of action, while Quenton Jackson is questionable. Jarace Walker has seen more playing time due to the injuries. He has shot below 35% in three of his past five games. The 22-year-old forward has contributed with 10 PPG and 5.2 RPG on the season.
Indiana has been a threat at home in the past week, posting a 3-2 mark in its past five games and covering the spread in all but one in that span. This includes a win against the Hornets and a defeat against the Pistons. Indiana is scoring an average of 110.2 points on the season, ranking them 29th. The Pacers have conceded 101 or fewer points in three of their past five games and are squandering an average of 119.5 points, pegging them 22nd.
Nuggets vs. Pacers Pick
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Rob Vinciletti | +1,570.00 |
| 2 |  Dan Kaiser | +1,223.00 |
| 3 |  Ross Benjamin | +1,000.00 |
| 4 |  Earle Sports Bets | +916.00 |
| 5 |  David Hess | +706.00 |
Spread Pick for Nuggets vs. Pacers
- Indiana Pacers +10.5 (5 units)
The Denver Nuggets have not been at their best in the past few weeks. They stand at 2-3 in their last five games and have only covered the spread in two games in that span. The Indiana Pacers are playing with some confidence, winning two of their past three games. They have been competitive in many of the defeats, covering in five of their past six games.
Furthermore, Denver scores a ton of points due to its potent efficiency from beyond the arc. They are shooting 39% from deep. They won't have their usual success against a Pacers squad that has been stingy defending threes, keeping opponents to a 32% mark, good for third in the NBA. The Pacers are playing their best defense of the season, keeping the opponent to an average of 108 points in their past five games.
Over/Under Pick for Nuggets vs. Pacers
- Over 239 (5 units)
I expect a shootout in this one. Denver has been exposing the opposition, netting an average of 127 points in its last five games. They have been just as dangerous on the road, scoring 123 or more points in five of their past six road games.
In addition, Indiana plays with a quick pace, ranking eighth in the NBA in tempo. They scored 119 points against the Wizards and 119 points in the defeat on Monday. The Nuggets have squandered an average of 123 points in their past five games. The over is a convincing 5-0 in the Nuggets' past five games.
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