Denver Nuggets vs Memphis Grizzlies Picks and Prediction for Wednesday November 11, 2026

The Denver Nuggets will be on the road Wednesday night for a Western Conference matchup against the Memphis Grizzlies inside FedExForum in Memphis, Tennessee. The game is scheduled to begin at 8 PM ET. Denver comes into Wednesday looking to bounce back following a 10-point road loss against Houston on Monday night. Memphis returns home after a difficult stretch that included a 31-point loss against Oklahoma City last week. Denver comes into this game a -4.5 favorite and a -156. Memphis are a +131, and the total is 228.5. Both teams will look to get back on track in this Western Conference matchup. Keep up with our NBA Picks.

Denver tries to stay above .500

The Denver Nuggets offense is averaging 115.3 points on 49% shooting from the field this season, but they've averaged just 105 points per game across their last two losses. Defensively, Denver is allowing 112.8 points per game this season. Jamal Murray is leading the Denver offense this season, averaging 24.2 points per game. Nikola Jokic is averaging 22.9 points, and he leads the team, averaging 10.1 rebounds and 9.1 assists. Christian Braun is averaging 13.5 points, and Spencer Jones is averaging 13 points per game. Aaron Gordon averages 12.3 points, and Cam Johnson is averaging 10.8 points per game. DeMar DeRozan is the seventh player on the roster in double digits, averaging 10.7 points in nearly 25 minutes per game off the bench.

Offensively, Denver had its problems in its last outing, scoring 100 points on 45% shooting and 28% from the outside. Defensively, Denver was outmatched, giving up 110 points on 45% shooting. Denver lost the rebounding battle by 12 and turned the ball over 12 times in the game. Jamal Murray led the Denver offense with 38 points on 23 shots.

Key Injury Report for Denver :

• Julian Strawther (Out) - Knee

Memphis looks for 2 in a row

The Memphis Grizzlies offense has been solid this season, averaging 117.9 points on 46% shooting from the floor. Defensively, Memphis is allowing 110.8 points per game this season, but they've given up an average of 123.3 points per game in their three losses. Ty Jerome is leading Memphis this season, averaging 26.6 points and 5.2 assists. Cam Boozer is second on the team with 15.6 points along with a team-leading 10 rebounds per game. Cedric Coward is averaging 13.8 points, and Isaiah Stewart is averaging 11.9 points per game. Jaylen Wells is the fifth player on the team in double digits, averaging 10.7 points per game.

Offensively, Memphis rolled last time out, pouring in 118 points on 53% shooting and 47% from the outside. Defensively, Memphis was the better team, giving up 102 points on 43% shooting. The Grizzlies won the rebounding battle by 10 and forced 14 turnovers in the win. Ty Jerome led Memphis with 27 points on 19 shots.

Key Injury Report for Memphis:

• Isaiah Stewart (GTD) - Knee
• Quinten Post (GTD) - Head
• Scotty Pippen Jr. (GTD) - Back
• Richie Saunders (Out) - Knee

Denver Nuggets vs Memphis Grizzlies Picks and Prediction

Pick: Denver Nuggets -4.5

Denver has the better overall roster in this matchup and should be able to take advantage of a Memphis team that has struggled defensively. Nikola Jokic gives the Nuggets a significant advantage in the paint with his ability to score, rebound, and create opportunities for his teammates. Memphis has the athleticism to challenge Denver in transition, but the Grizzlies could have trouble defending the Nuggets in the half-court. Denver will need to avoid careless turnovers and limit second-chance opportunities to keep Memphis from establishing momentum. Look for the Nuggets to rely on their experience and offensive execution to secure the road victory.

Secondary: Over 228.5

Memphis will need to push the pace to have success against Denver, which should create plenty of offensive opportunities for both teams. The Grizzlies have the speed and athleticism to attack in transition, but that approach could leave them vulnerable against a Denver offense capable of scoring efficiently. Jokic should have success creating quality looks for his teammates, while the Nuggets have enough perimeter shooting to take advantage of defensive breakdowns. Memphis will get its share of scoring opportunities playing at home, but Denver should be able to match that production throughout the night. Expect an offensive matchup with both teams contributing to a game that finishes over the total.

Final Picks: Denver Nuggets -4.5 and Over 228.5