Minnesota Timberwolves vs New York Knicks Prediction and Picks - November 5, 2025

By: Dean Whitaker Published 11/05/2025, 07:00 AM ET
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NBA action on Wednesday evening, and we have a Minnesota Timberwolves vs New York Knicks prediction locked and loaded for you. Minnesota comes in off a 125-109 road win over the Nets to move to 4-3 on the year. The Knicks are also at 4-3 on the year, and they come in off a 119-102 home win over Washington. These teams have split the season series in each of the last five years. Read on to see our Timberwolves vs Knicks prediction.

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T-Wolves Pound The Nets

Minnesota rolls into Madison Square Garden fresh off a convincing 125-109 win over the Brooklyn Nets, a game where Julius Randle notched his first triple-double as a Timberwolf. Randle’s 19 points, 11 rebounds, and 10 assists set the tone, while Donte DiVincenzo poured in 25 points and Jaden McDaniels added 22. Even without Anthony Edwards, who remains sidelined with a hamstring injury, the Wolves looked sharp and efficient, shooting 56 percent from the field and dominating the glass with a 53-40 rebounding edge. That kind of balance has been their calling card early in the season, and it’s what makes them dangerous against a Knicks team that’s been thriving at home.

The Timberwolves’ offense has been humming thanks to their ability to spread the floor and share the ball. Randle has seamlessly fit into his new role, giving Minnesota a versatile forward who can score inside, stretch the defense, and create for others. Rudy Gobert continues to anchor the paint, pulling down double-digit rebounds while providing rim protection, and Naz Reid has been a spark off the bench with his shooting and energy. Minnesota’s ball movement has been crisp, with 33 assists against Brooklyn, and that unselfish style has allowed them to weather Edwards’ absence without losing their offensive rhythm.

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Defensively, Minnesota has been up and down, but when they’re locked in, they can be suffocating. Gobert’s presence in the middle forces opponents to settle for jumpers, and McDaniels’ length on the perimeter makes life difficult for opposing wings. The challenge against New York will be containing Jalen Brunson’s dribble penetration while also keeping Karl-Anthony Towns from getting comfortable inside. If the Wolves can limit second-chance points and avoid foul trouble, they’ll give themselves a real chance to steal one on the road.

Knicks Rout The Wizards At Home

The Knicks enter this matchup riding a two-game winning streak, capped by a 119-102 victory over the Washington Wizards on Monday night. Karl-Anthony Towns was the star of the show, dropping a season-high 33 points to go along with 13 rebounds, reminding everyone why New York made the blockbuster trade to bring him in. Jalen Brunson chipped in 16 points and nine assists, while OG Anunoby and Jordan Clarkson provided steady scoring support. The Knicks are now 4-0 at Madison Square Garden this season, and the energy in the building has been a big factor in their early success.

Offensively, New York has been leaning on Towns as the centerpiece, and he’s responded with six double-doubles in seven games. His ability to stretch the floor opens up driving lanes for Brunson, while Anunoby and Mikal Bridges give the Knicks reliable two-way production on the wings. Josh Hart continues to do all the little things—rebounding, defending, and pushing the pace in transition—while Clarkson has been a spark plug off the bench. The Knicks have also been deadly from three-point range at home, knocking down 20 triples in their win over Chicago and 15 more against Washington.

Defensively, the Knicks have been solid, holding opponents to just over 113 points per game. Towns has been more engaged on that end, protecting the rim and cleaning the glass, while Anunoby and Bridges give them two elite perimeter stoppers. The key against Minnesota will be limiting Randle’s playmaking and keeping Gobert off the boards. With Mitchell Robinson still being managed carefully after ankle surgeries, the Knicks will need a collective effort inside to match Minnesota’s size. Still, with the Garden crowd behind them and momentum building, New York looks poised to defend its home floor once again.

Minnesota Timberwolves vs New York Knicks Pick

Timberwolves vs Knicks Spread Pick

  • New York -4 (2 Units)

Backing the Knicks -4 makes sense given how dominant they’ve been at Madison Square Garden to start the season. They’re 4-0 at home and have looked energized by the crowd, with Karl-Anthony Towns settling in as the focal point of the offense. His ability to stretch the floor and punish mismatches inside has opened up driving lanes for Jalen Brunson, while OG Anunoby and Mikal Bridges provide steady two-way play on the wings. Against a Minnesota team still adjusting without Anthony Edwards, New York’s balance and depth give them a clear edge in controlling tempo and dictating the style of play.

Defensively, the Knicks also match up well here. Towns and Mitchell Robinson can battle Rudy Gobert on the glass, while Anunoby and Bridges are capable of making life difficult for Julius Randle, who’s been carrying the Timberwolves’ offense in Edwards’ absence. New York has been sharp in closing out on shooters at home, and if they can limit Minnesota’s second-chance points, the Wolves will struggle to keep pace. With the Garden crowd behind them and momentum building, the Knicks are well-positioned to cover the number and extend their strong home start.

Timberwolves vs Knicks Over/Under Pick

  • Under 229.5 (2 Units)

The under 229.5 feels like the right angle because both the Knicks and Timberwolves lean on defense and half-court execution more than track-meet pace. New York has been especially tough at home, holding opponents in check with their length on the perimeter and rim protection inside, while Minnesota’s size with Rudy Gobert and Jaden McDaniels makes scoring in the paint a grind. With Anthony Edwards sidelined, the Wolves’ offense loses some explosiveness, and the Knicks have been content to slow games down and rely on efficiency rather than volume. All signs point to a more controlled, defensive battle that stays under the number.

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