Philadelphia 76ers vs Boston Celtics Picks and Predictions for Tuesday, April 21, 2026
Use Code WWWC The Philadelphia 76ers continue their road trip Tuesday night with another game in TD Garden at 7:00 PM against the Boston Celtics for game 2 of their first-round matchup in the Eastern Conference playoffs, and we have you ready to roll with our Philadelphia vs Boston prediction. Philadelphia finished the regular season with 45 wins and 37 losses, but comes into this matchup having lost 2 of the last 5 after a blowout 32-point loss in Game 1 of this series. The Boston Celtics stay home on Tuesday after finishing the regular season with 56 wins overall. Boston comes into Game 2 of this series having won 4 of the last 5, including 3 straight after their victory over Philadelphia in Game 1 of this set. Read more about this Philadelphia vs Boston prediction! Struggling with handicapping? Try our NBA Predictions!
Philadelphia is desperate for a win
The Philadelphia offense has averaged 115.9 points on 46% shooting from the floor this season, but Philadelphia has averaged only 96.5 points per game over its last 2 losses. Offensively, Philadelphia struggled immensely in Game 1 of this series, scoring just 91 points on 39% shooting and 17% from beyond the arc. Philadelphia lost the rebounding battle by 3 and turned the ball over 15 times in the game. Tyrese Maxey leads the Philadelphia offense this season, averaging 28.3 points o and 6.6 assists per game. Joel Embiid has been vital for the Sixers this season, posting a second-best 26.9 points per game, though he played just 38 times.
Tyrese Maxey led the show for the Philadelphia offense in Game 1 of this series with 21 points on 20 shots. Paul George added a second-best 17 points on 8 shots, and rookie VJ Edgecombe added 13 points in 34 minutes. Kelly Oubre Jr. was the 4th starter for Philadelphia in double digits with 10 points on 14 shots. The Philadelphia bench combined to score 27 points between 7 players.
Key Injury Report for Philadelphia:
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- Joel Embiid (Out) - Abdomen
Boston looks to defend its home floor
The Boston offense has fared well enough this season, averaging 114.9 points on 47% shooting from the floor, and the Celtics have averaged 123.25 points per game over their last 4 wins. Boston was the far better team in this matchup last time out, scoring 123 points on 50% shooting and 36% from beyond the arc. The Celtics pulled in 43 rebounds, including 5 on the offensive side. Jaylen Brown is the offensive leader this season for the Celtics, averaging 28.7 points per game. Jayson Tatum was second on the Boston roster this season, averaging 21.8 points per game after playing 16 games following his injury last season.
Jaylen Brown led the way for the Boston offense in their last outing with 26 points on 21 shots in 30 minutes. Jayson Tatum chipped in a second-best 25 points on 17 shots. Neemias Queta added 13 points in 15 minutes, and Sam Hauser scored a fourth-best 12 points on 6 shots. Derrick White was the 5th starter for Boston in double digits with 10 points in 33 minutes of action. Payton Pritchard led the way off the Boston bench with 12 points in 34 minutes of action.
Key Injury Report for Boston:
- None
Philadelphia vs Boston Pick
- Philadelphia vs Boston Spread Pick
Boston is the better team in this matchup, and it showed in Game 1 of this series. Philadelphia will again be without a former MVP in this matchup, giving Boston a huge edge. Look for Boston to again dominate this matchup from the opening minutes as they take full control of the series in game 2. The Boston Celtics will roll Tuesday night to an easy win at home against the Philadelphia 76ers.
- Philadelphia vs Boston Over/Under Pick
Both teams will score the ball well, but Philadelphia will be without a chunk of scoring in this matchup. Despite Philadelphia missing a big piece, look for both teams to score in bunches in this game. Expect both teams to run it up Tuesday night as each looks for an all-important game 2 victory. Take Boston to get the blowout victory in this matchup, but the total will go over the number as each offense plays well.
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