Philadelphia 76ers vs New York Knicks Picks and Predictions for Wednesday, May 6, 2026

By: Cameron Ross Published 05/06/2026, 05:00 AM ET
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The Philadelphia 76ers stay on the road Wednesday night with another game inside Madison Square Garden in New York for Game 2 of the Eastern Conference semifinals against the New York Knicks at 7:00 PM, and we have you ready to roll with our Philadelphia vs New York prediction. Philadelphia came into this series running hot on a 3-game winning streak, but was obliterated in Game 1, following a near-40-point loss. The New York Knicks stay home Wednesday night, running hot on a 4-game winning streak after their blowout win in Game 1 of this set. Read more about this Philadelphia vs New York prediction! Struggling with handicapping? Try our NBA Predictions!

Philadelphia looks to bounce back

Offensively, Philadelphia has averaged 115.9 points on 46% shooting from the floor this season, but the 76ers have averaged just 97 points in each of their last 2 losses. Offensively, Philadelphia struggled in Game 1 of this series, scoring just 98 points on 41% shooting and 37% from beyond the arc. Philadelphia pulled in 28 rebounds but turned the ball over 19 times in the loss. Paul George led the way for the Philadelphia offense with 17 points on 11 shots. Joel Embiid added a second-best 14 points on 11 shots. Kelly Oubre Jr. and VJ Edgecombe both scored 12 points, while Tyrese Maxey added 13 points as the 5th Philadelphia starter in double digits.

Joel Embiid is leading Philadelphia in the postseason, averaging 25.2 points and 8 rebounds per game. Tyrese Maxey is second on the roster with 25.1 points, along with a team-leading 6 assists. Paul George is averaging 17.4 points, and rookie VJ Edgecombe is averaging 14.8 points per game. Kelly Oubre Jr. is averaging 9.6 points in just under 33 minutes per game.

Key Injury Report for Philadelphia:

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New York tries to keep it rolling

Offensively, New York has been a juggernaut this season, averaging 116.5 points on 48% shooting from the floor, and the Knicks have upped their scoring to 128.5 points per game during their current 4-game winning streak. Offensively, New York dominated Game 1, scoring 137 points, including 74 in the first half, on 63% shooting, and 51% from beyond the arc. New York won the rebounding battle by 11 and pulled in 8 offensive rebounds. Jalen Brunson led the way for the New York offense with 35 points on 18 shots. OG Anuony chipped into the New York offense in Game 1, scoring 18 points on 8 shots. Karl Anthony-Towns and Mikal Bridges both added 17 points each.

Jalen Brunson is leading the New York offense in the playoffs, averaging 27.6 points per game. OG Anunoby is second on the roster with 21 points, and Mikal Bridges is averaging a fourth-best 11 points per game. Big man Karl Anthony-Towns is averaging a 3rd-best 18.4 points per game, along with a team-leading 10.6 rebounds and 6 assists per game.

Key Injury Report for New York:

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Philadelphia vs New York Pick

  • Philadelphia vs New York Spread Pick

The New York Knicks dominated every aspect of this matchup in Game 1 and will do so again in Game 2. The Knicks took the 76ers hearts as Philadelphia pulled their starters in the third quarter. Look for New York to continue their hot hand in this matchup as they again dominate Philadelphia, start to finish. Take the Knicks on Wednesday night to get an easy win and cover at home to take full control of this series.

  • Philadelphia vs New York Over/Under Pick

Both teams are scoring the ball well, and Philadelphia did their part in Game 1 towards the total despite the blowout. Expect both offenses to again perform at a high rate Wednesday night, as points will continue to come in bunches. Take the over Wednesday night as the New York Knicks do the work to take full control of this series with another victory at home against the Philadelphia 76ers.

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