Portland Trail Blazers vs. Detroit Pistons Picks and Prediction for Friday, December 5, 2025
Use Code WWWC It’s an interconference tilt on the parquet floor in the Motor City as the Portland Trail Blazers clash with the Detroit Pistons Friday night, and we have things covered with our Trail Blazers vs. Pistons prediction. Portland dropped Cleveland 122-110 at home Wednesday night in their previous game, winning outright as a 10-point underdog. Detroit fell 113-109 on the road to Milwaukee in their previous game Wednesday night, losing outright as a 4.5-point favorite. In the all-time regular season series between the teams, the Trail Blazers own a 71-58 advantage, but the Pistons have won three straight meetings, including a 119-112 road win in the most recent meeting on March 9. Read more about this Trail Blazers vs. Pistons prediction! No air balls here—only slam dunks with our NBA Picks!
Portland Seeking to Earn Back-to-Back Road Wins
Portland snapped a three-game skid as they downed Cleveland in the second game of a back-to-back set Wednesday night on the road. The Trail Blazers entered Thursday 9-13 and stood fourth in the Northwest Division, 12 games behind the Thunder for the top spot. Against Cleveland, Portland trailed 17-9 four minutes into the game before regrouping to lead by three after the opening quarter. The Trail Blazers pushed the lead to 10 at the half and led the rest of the way en route to the victory. Portland shot 43.5% from the floor, including 14 of 34 from beyond the arc, and won the battle of the boards by a 54-45 margin. Deni Avidja led the Trail Blazers with 27 points, eight rebounds and seven assists in the win.
On the year, the Trail Blazers are 13th in the league in scoring offense with 118.4 points per game. Portland is 6th in the league in rebounding with 45.9 boards a game and 25th in assists as they hand out 24.9 assists per game this season. The Trail Blazers are 25th in scoring defense by allowing 120.6 points per night. Deni Avidja is leading the team with 25.8 points plus 7.1 rebounds and 6.2 assists per game this season, while Shaedon Sharpe kicks in 20.9 points per contest. Jerami Grant puts up 19 points a night while Donovan Clingan (10 points, 10.2 rebounds) and Jrue Holiday (16.7 points, 5.3 rebounds, 8.3 assists) are solid scoring options. Robert Williams III, Toumani Camara (12.9 points, 5.5 rebounds), Blake Wesley, Kris Murray, Caleb Love, Matisse Thybulle and Duop Reath have been a part of the Trail Blazers’ rotation this season. Portland is 28th in the league in field goal percentage as they shoot 44.5% from the field as a team this season. The Trail Blazers are 11th in the league in threes per game as they hit 13.8 triples per game and are 29th in three-point percentage as they hit 32.9% from beyond the arc. Portland is average at the free throw line, ranking 15th by converting 79% of their attempts this season.
Key Injury Report for Trail Blazers:
- Guard Damian Lillard (Achilles) is out.
- Guard Scoot Henderson (hamstring) is out.
- Guard Jrue Holiday (calf) is out.
- Guard Matisse Thybulle (thumb) is out.
- Guard Blake Wesley (foot) is out.
- Forward Kris Murray (hip) is questionable.
- Center Robert Williams III (knee) is questionable.
- Center Donovan Clingan (leg) is questionable.
Pistons Try to Extend Central Division Edge
Detroit saw their two-game win streak snapped as they were downed by the Bucks on the road Wednesday night. The Pistons entered Thursday 17-5 and held a 4.5-game lead on the Cavaliers for the top spot in the Central Division standings. Against Milwaukee, Detroit simply ran out of steam down the stretch as they played their fourth game in six nights. The Pistons were up nine after the opening quarter, by three at the half and by seven after three quarters only to get outscored 35-24 in the final quarter to wind up with the loss. Detroit shot 40% from the field, including 14 of 43 from three-point range, and allowed the Bucks to shoot 48.8% from the floor in the contest. Tobias Harris paced the Pistons with 20 points in the loss.
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On the year, the Pistons are 14th in the league in scoring offense as they average 118.3 points a game. Detroit is 2nd in rebounding with an average of 46.9 boards per contest and 14th in assists by dishing out 26 dimes a night. The Pistons are 6th in the league in scoring defense as they give up an average of 113.2 points per contest. Cade Cunningham leads the way offensively for the Pistons with 27.6 points plus 6.5 rebounds and 9.2 assists per game. Ronald Holland II, Ausar Thompson (11.6 points, 6.1 rebounds, 2.9 assists) and Isaiah Stewart (9.6 points, 6.4 rebounds) are good secondary scoring options. Jalen Duren (19 points, 11.5 rebounds), Tobias Harris (15.1 points, 5.2 rebounds), Tolu Smith, Duncan Robinson (12.6 points), Caris LeVert, Jaden Ivey, Paul Reed, Daniss Jenkins, Javonte Green, and Chaz Lanier are looked at to be contributors for coach J.B. Bickerstaff. Detroit is 9th in the league in field goal percentage as they shoot 48.2% from the floor as a team. The Pistons are 29th in the league in threes per game as they hit 11.1 triples per contest, while they are 21st in three-point percentage as they connect on 35.1% of their attempts from beyond the arc. Detroit is below average at the charity stripe, ranking 28th by shooting 74.8% at the line as a team.
Key Injury Report for Pistons:
- Forward Bobi Klintman (ankle) is out.
- Guard Marcus Sasser (hip) is questionable.
- Forward Duncan Robinson (ankle) is questionable.
Trail Blazers vs. Pistons Pick
Trail Blazers vs. Pistons Spread Pick
- Pistons -6 (4 units)
Granted, Detroit is playing their fifth game in eight nights here but they are getting back to full strength. The Pistons have bolted to the top of not only the Central Division but the Eastern Conference standings as well. Portland is dealing with a slew of injuries right now as their starting backcourt (Holiday, Henderson) is missing, while several other key pieces are questionable or out here as well. The Trail Blazers are better on the road (6-7) than at home (3-6) this season but they have to deal with a Pistons squad that is 8-2 at home with a more complete rotation right now. Take the Pistons at home in this contest.
Trail Blazers vs. Pistons Over/Under Pick
- Under 237.5 (4 units)
Portland has seen the over post a 14-11 mark in their first 22 games this season, entering Friday. The Trail Blazers are 13th in the league in scoring offense, 17th in offensive efficiency and 3rd in adjusted tempo with an average of 102.1 possessions a night this season. They have stayed under the number in four of their last six games. Detroit stands 14th in offensive efficiency, 14th in scoring offense, and 10th in tempo with 101 possessions per game. The Pistons have stayed under the number in 11 of their 22 games this season, entering this one, and have stayed under the number in four of their last five games. With Portland dealing with a slew of injuries, this game winds up short of the number.
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