Portland Trail Blazers vs San Antonio Spurs Picks, Prediction and Odds for Game 2

By: Kyle Kargel Published 04/21/2026, 08:05 AM ET
Thunder vs Spurs Prediction Game 3
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The NBA Playoffs roll on as the Portland Trail Blazers head back to San Antonio looking to even up their first-round series with the Spurs. After a 111-98 loss in Game 1 that still showed plenty of fight from the road side, Portland walks into a spot where bettors are starting to wonder whether the number is still too generous toward the favorite. If you are hunting for more NBA picks and want to see how this series is shaping up for Game 2, we have the full breakdown, spread and total analysis, and a projected final score waiting below.

Quick Picks and Prediction

  • Spread Pick: Portland +11.5
  • Total Pick: Under 220.5
  • Projected Final Score: San Antonio 112, Portland 104

Odds and Line Movement

The market has nudged this one around as sharp money and public action have sorted themselves out. Both the spread and the total have seen some minor tightening since opening, and the final numbers are worth a close look before pulling the trigger on any Game 2 wager.

Opening Odds

Team Spread Total
Portland +12.5 (-110) O 221.5 (-110)
San Antonio -12.5 (-110) U 221.5 (-110)

Current Odds

Team Spread Total
Portland +11.5 (-106) O 220.5 (-112)
San Antonio -11.5 (-114) U 220.5 (-108)

Line Movement - Spread

Date Time Portland San Antonio
04/19 11:54:45PM 11½-106 -11½-114
04/19 11:43:52PM 12-110 -12-110
04/19 11:37:23PM 12-110 -12-110
04/19 11:37:16PM 12½-110 -12½-110

Line Movement - Total

Date Time Over Under
04/19 11:46:15PM 220½-112 220½-108
04/19 11:45:56PM 220½-110 220½-110
04/19 11:43:52PM 221½-110 221½-110
04/19 11:37:16PM 221½-110 221½-110

Trail Blazers vs Spurs Key Matchups and Handicap

San Antonio earned a 111-98 home win in Game 1, which was barely enough margin to cover the 12.5-point spread. Victor Wembanyama was fantastic, scoring 35 points in 33 minutes while going 5-of-6 from three-point range. All things considered, we saw enough from the Blazers to believe that they can remain competitive in this series. A lot of things didn't go Portland's way on Sunday, but the Blazers "only" lost by 13.

Prior to Game 1, we mentioned how important the three-point line was going to be. The Blazers attempted the third-most three-point attempts in the league this season, but Portland only shot 26.3-percent from beyond the arc on Sunday. San Antonio finished with a 15-10 advantage in made three-pointers, but that is an area where the Blazers can quickly close the gap.

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Portland

Missed three-pointers lead to long rebounds and long rebounds lead to fast-break opportunities. Portland missed a lot of three-pointers, which led to 20 fast-break points by the Spurs. Now that Game 1 is over and in the books, Portland might benefit from Wembanyama going 5-of-6 from beyond the arc because he may be encouraged to stay out there.

If you asked Blazers' head coach Tiago Splitter "Would you rather have a 7-foot-6 opponent shooting threes or dominating in the paint?" he would probably respond with "Let him have the threes." Portland only committed ten turnovers on Sunday, which is an encouraging sign. Deni Avdija looked very comfortable in his playoff debut, scoring 30 points with ten rebounds while shooting 12-of-21 from the field.

San Antonio

Victor Wembanyama set the tone for San Antonio in Game 1 with a 35-point performance in just 33 minutes of action. His 5-of-6 showing from three-point range was the difference in the game, and it stretched Portland's defense in ways the Blazers were not prepared to handle. If Wembanyama is encouraged to stay on the perimeter in Game 2, that may actually work in Portland's favor, as it keeps him away from the dominant paint presence he can be at 7-foot-6.

The 15-10 advantage in made three-pointers and the 20 fast-break points were the two biggest separators in Game 1, and both are tied directly to Portland's struggles from deep. If the Blazers shoot a more typical percentage from beyond the arc, the math of this game changes in a hurry.

  • San Antonio covered the 12.5-point spread in Game 1 by the slimmest of margins, winning by 13.
  • Portland only committed ten turnovers in Game 1, an encouraging sign for a road underdog.
  • Portland shot just 26.3-percent from three-point range in Game 1 after entering the playoffs with the third-most three-point attempts in the league.
  • San Antonio outscored Portland 20-? in fast-break points, largely off of missed Blazers three-pointers.
  • Victor Wembanyama went 5-of-6 from three-point range in Game 1, a pace that is unlikely to be sustained.

POR vs SAS Key Injuries and Notes

  • Deni Avdija made his playoff debut in Game 1 and scored 30 points with ten rebounds on 12-of-21 shooting.
  • Victor Wembanyama played 33 minutes in Game 1, leaving room for expanded usage in Game 2 if needed.
  • Portland head coach Tiago Splitter will likely be comfortable with Wembanyama continuing to shoot from deep rather than operating in the paint.

Trail Blazers vs Spurs ATS and Total Picks

  • ATS Pick: Portland +11.5
  • Total Pick: Under 220.5

If Portland can close the gap at the three-point line, that is going to create a ripple effect through a lot of other areas and we believe the Blazers can stay within this number. The spread has already come down from 12.5 to 11.5, which suggests the market agrees that the gap between these teams is not quite what Game 1's final margin implied. With Portland's low turnover count and Deni Avdija's comfort level established, the Blazers should be able to scrape together enough possessions and points to hang around. On the total, a regression in three-point shooting for San Antonio combined with continued struggles from Portland's perimeter game points toward a lower-scoring affair, making the under the more attractive side.

Final Score Prediction

  • Final Score Prediction: San Antonio 112, Portland 104
  • Spread Result: Portland covers +11.5
  • Total Result: Under 220.5

How to Bet Blazers vs Spurs Game 2

This is a game where shopping for the best number matters more than usual. The spread has already moved from 12.5 down to 11.5, and getting the extra half-point could be the difference between a winning ticket and a push if Portland loses by exactly 12. Anyone looking to play Portland +11.5 should be prioritizing sportsbooks that are still offering the most favorable juice on the underdog.

If you prefer risk-free or low-stakes action on a playoff spot like this, social sportsbooks give you a way to get in the game without dipping into your bankroll. For traditional real-money wagering, grabbing the bet365 bonus code is a smart way to add some extra value to your Game 2 ticket, especially if you want to parlay the Blazers spread with the under. If you like the sweepstakes-style setup where you can play for cash prizes without the traditional sportsbook model, the fliff promo code is another strong option for this matchup.

Whichever route you take, the key with Blazers at Spurs Game 2 is locking in Portland +11.5 before the number moves any further and pairing it with the under at 220.5. Game 1 showed that Portland can hang, and Game 2 is where that closer scoreline finally shows up on the scoreboard.

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