Portland Trailblazers vs Los Angeles Lakers Picks and Prediction for Friday November 6, 2026

By: Cameron Ross Published 11/06/2026, 12:29 AM ET

The Portland Trail Blazers will be on the road Friday night for a matchup against the Los Angeles Lakers inside Crypto.com Arena in Los Angeles, California. The game is scheduled to tip off at 10:00 PM ET, with coverage on Prime Video. Portland comes into Friday night rolling this season with six wins through its first seven games, having won four of the last five, including three in a row following a 13-point road victory against the Phoenix Suns. The Los Angeles Lakers are also red hot, sitting at 7-2 overall and having won four of their last five games, including three straight following a 13-point road victory against the Sacramento Kings in their last outing. The Lakers are 2.5-point favorites at -136 on the moneyline Friday night. Portland is a +115 and the total is 233.5. Stay in the action with our NBA Picks.

Portland tries to extend their streak

The Portland Trail Blazers offense is averaging 121.9 points per game on 48% shooting from the floor this season. Defensively, Portland has been even better, holding opponents to 110.7 points per game and allowing an average of just 106.3 points during its current three-game winning streak. Deni Avdija leads the Portland offense this season, averaging 23.4 points and a team-high 6.4 assists per game. Damian Lillard is averaging 20.1 points, while Ja Morant is adding 15.8 points per game. Toumani Camara is averaging 13.7 points, while big man Donovan Clingan is contributing 12 points and a team-high 10.6 rebounds per game.

The Portland offense rolled in its last outing, pouring in 132 points on 51% shooting from the floor and 36% from beyond the arc. Defensively, Portland did enough to secure the victory, allowing 119 points on 45% shooting. The Trail Blazers won the rebounding battle by eight and forced 12 turnovers in the win. Damian Lillard led the Portland offense with 25 points on 17 shots.

Key Injury Report for Portland:

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  • Vit Krejci (Out) - Ankle
  • Ja Morant (Out) - Hamstring
  • Shaedon Sharpe (Out) - Knee

Los Angeles goes for 4 in a row

The Los Angeles Lakers offense is averaging 121.8 points per game on 51% shooting from the floor this season, including an average of 128.3 points during their current three-game winning streak. Defensively, Los Angeles has held its own, allowing 113.9 points per game through nine games played. Luka Doncic leads the Los Angeles offense this season, averaging 38.5 points and a team-high eight assists per game. Austin Reaves is second on the roster, averaging 23.3 points, while Walker Kessler is adding 14.4 points and a team-high 10.2 rebounds per game. Ziaire Williams is fourth on the team, averaging 10.7 points per game.

The Los Angeles offense did the work in its last outing, scoring 116 points on 45% shooting from the floor and 32% from beyond the arc. Defensively, the Lakers were fantastic, allowing just 103 points on 39% shooting. Los Angeles pulled in 38 rebounds and forced 18 turnovers in the victory. Luka Doncic led the Lakers offense with a near triple-double of 40 points, nine rebounds, and seven assists on 23 shots.

Key Injury Report for Los Angeles:

  • Adou Theiro (GTD) - Knee

Portland Trail Blazers vs Los Angeles Lakers Picks and Prediction

Pick: Los Angeles Lakers -2.5

Los Angeles has the offensive firepower and home-court advantage needed to take control of this matchup. Portland has played well recently and has shown the ability to compete on the road, but the Lakers have enough talent to create problems throughout the game. Los Angeles should find success attacking the basket and generating quality perimeter opportunities against Portland's defense. The Trail Blazers will need to control the glass and limit easy transition opportunities to remain competitive. Look for the Lakers to establish their offense early and make enough plays down the stretch to secure the home victory.

Total Pick: Over 233.5

Both teams have shown the ability to score at a high level, and this matchup has the potential to turn into an offensive battle. Portland has been productive in recent outings, while Los Angeles has enough scoring options to consistently put pressure on opposing defenses. The Lakers should find success attacking the paint, while Portland will look to push the tempo and create opportunities in transition. Neither team has to rely on one offensive weapon to produce points, giving both sides multiple ways to score. Expect plenty of offensive production throughout the game as the total goes over.

Final Picks: Los Angeles Lakers -2.5 and Over 233.5

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