San Antonio Spurs vs Portland Trail Blazers Picks, Prediction and Odds For April 26 2026

By: Kyle Kargel Published 04/26/2026, 09:05 AM ET
Spurs vs Trail Blazers Game 4 prediction
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The San Antonio Spurs head back to the Moda Center on Sunday afternoon looking to take a commanding 3-1 series lead over the Portland Trail Blazers, even with the status of Victor Wembanyama still up in the air. With first-round series swinging on every possession, this Game 4 matchup is loaded with betting value, and we have the full breakdown below alongside our latest NBA picks for the rest of the playoff slate.

Quick Picks and Prediction

  • Spread Pick: San Antonio Spurs -5.5 (-104)
  • Total Pick: Under 218.5 (-114)
  • Projected Final Score: San Antonio 112, Portland 104

Odds and Line Movement

Below is a snapshot of how the market opened and where it currently sits ahead of tipoff. Public money has poured in heavily on Portland's side of the spread, but the line has actually moved in the opposite direction, suggesting sharp action on the Spurs.

Opening Odds

Team Spread Total
San Antonio -5½ (-108) O 218½ (-110)
Portland +5½ (-112) U 218½ (-110)

Current Odds

Team Spread Total
San Antonio -5½ (-104) O 218½ (-106)
Portland +5½ (-118) U 218½ (-114)

Line Movement - Spread

Date Time San Antonio Portland Public ($, #)
04/25 11:42:44 AM -5½ -108 5½ -112 POR 92%, POR 75%
04/25 01:23:21 AM -5½ -104 5½ -118

Line Movement - Total

Date Time Over Under Public ($, #)
04/25 08:53:07 AM 218½ -110 218½ -110
04/25 08:50:28 AM 218½ -108 218½ -112
04/25 01:23:21 AM 218½ -106 218½ -114

Spurs vs Trail Blazers Key Matchups and Handicap

San Antonio used a big fourth quarter to escape Game 3 in Portland without Victor Wembanyama. The Spurs' All-Star suffered a concussion in Game 2 and was unable to get cleared prior to Friday's contest. He remains in the NBA's concussion protocol as of Sunday morning and he is listed as questionable for this afternoon's contest.

Stephon Castle and Dylan Harper combined to score 60 points as the Spurs were forced to use more of a small-ball lineup without the Defensive Player of the Year roaming the paint. That backcourt explosion is what gave San Antonio the cushion it needed late, and it proved that this team has scoring depth even when the franchise centerpiece is sidelined.

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Portland's Jrue Holiday and Scoot Henderson enjoyed a productive night, but they didn't get much help. Outside of that duo, the rest of the Blazers' roster combined to shoot 31.5-percent from the field. Holiday and Henderson each made five three-pointers while the rest of the Blazers went 4-of-19 (21.1-percent) from beyond the arc. That's a level of shot-making concentration that's almost impossible to replicate game after game in a playoff series.

Playing against the Blazers without Wembanyama should have felt pretty familiar for the Spurs because they did it three times in the regular season. Following Friday night's victory, San Antonio is now 3-1 straight-up and against the spread versus Portland without Wembanyama in the lineup. All three wins came by double-digits and we're comfortable going back to that same well once again.

In Friday's Game 3, Portland had more free throw attempts, won the turnover battle, generated more offensive rebounds and still lost by double digits. That's not a great sign moving forward for a Blazers team that has now dropped multiple games in this series despite winning several "hustle" categories. When a team is generating extra possessions and still losing by 10-plus, it's usually a sign that the offensive ceiling just isn't there.

The Spurs are now 3-1 straight-up and against the spread versus Portland in games without Wembanyama, and the margin in those wins has been double digits in all three. That trend speaks directly to this matchup, where the price is sitting at -5½ regardless of the franchise center's availability.

Key Injuries and Notes - SAS vs POR

The biggest variable on the board is once again Wembanyama, who remains in the NBA's concussion protocol and is listed as questionable for Sunday's tipoff. Even if he is unable to clear protocol in time, the Spurs have already shown they can win this matchup without him.

On the Portland side, Blazers head coach Tiago Splitter will likely have to tweak his rotations ahead of Sunday's game because the bench matchup has not gone his way. Jerami Grant posted a -25 plus/minus rating in just 19 minutes on the court in Game 1, and he followed that up with a -19 plus/minus rating in 23 minutes in Game 3. Portland's production has seen a steep decline with Grant on the court, and Splitter will likely have to make some tough decisions around his usage during the rest of this series.

Spurs vs Trail Blazers ATS and Total Picks

  • Against the Spread: San Antonio -5.5 (-104). The Spurs are 3-1 ATS in this matchup without Wembanyama and all three wins came by double digits. Even with the public hammering Portland, the line has moved toward San Antonio, which tells us where the sharper money sits.
  • Total: Under 218.5 (-114). Portland's supporting cast shot 31.5-percent from the floor in Game 3, and the small-ball Spurs lineup has been efficient but methodical. With Holiday and Henderson likely to regress from their five-make night from deep, the Under is the play.

Final Score Prediction

We're projecting another double-digit win for San Antonio, in line with the pattern we've seen all season when these two teams meet without Wembanyama on the floor. Castle and Harper continue to carry the offensive load, while Portland struggles to find consistent scoring outside of its starting backcourt.

  • Final Score Prediction: San Antonio Spurs 112, Portland Trail Blazers 104

How to Bet Spurs vs Trail Blazers Game 4

This matchup is one of the better-priced spots on the NBA playoff slate, especially with the line moving toward the Spurs despite heavy public action on Portland. If you're looking to get this game in, there are a few smart ways to do it depending on your situation.

For bettors who don't have access to traditional sportsbooks or live in a state where online wagering isn't legal, social sportsbooks are a great way to get action on Game 4 with sweeps coin promotions and free daily play. They've become one of the fastest-growing options in the country and offer real-money redemptions in most states.

If you're in a regulated market, new users can grab a strong sign-up offer with our bet365 bonus code, which is one of the better welcome promotions for NBA playoff betting and applies directly to spreads, totals, and player props for this San Antonio vs Portland matchup.

And for casual bettors who want a low-stakes way to get in on the action, the fliff promo code is another solid option. Fliff offers daily login rewards and a sweeps-style format that's perfect for parlaying NBA playoff sides and totals like the ones we've laid out above.

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