Spurs vs. Nuggets Picks and Prediction for Friday, November 28, 2025

By: Michael Briggs Published 11/28/2025, 03:15 AM ET
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On Friday, the San Antonio Spurs will face the Denver Nuggets at Ball Arena, and we have you ready to go with our Spurs vs. Nuggets prediction, odds, and preview. Tip-off from the Mile High City is at 9:30 p.m. ET.

The Nuggets are 10.5-point spread favorites, and the game total is 236.5 points.

The Spurs won two of three against the Nuggets last season. Denver is 6-4 SU/4-6ATS in its last ten games against San Antonio, and the under went 7-3. If you want the Spurs vs. Nuggets prediction, read on to get our topΒ NBA predictionsΒ and increase your bankroll!

Spurs haven't slowed down much without Wemby and Castle

San Antonio (12-5 SU, 9-7-1 ATS, and 8-9 O/U) beat Portland 115-102 on Wednesday. The Spurs are 7-3 SU and 5-5 ATS in their last ten games, and the over/under was split 5-5.

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F Victor Wembanyama leads San Antonio in scoring at 26.2 points per game on 50.2 percent shooting. He's currently sidelined with a calf injury. A few Spurs to watch on Friday against the Nuggets are G De'Aaron Fox (23.5 PPG and 6.1 APG), G Dylan Harper (14.0 PPG and 4.0 RPG), and G Devin Vassell (13.9 PPG and 3.6 RPG).

San Antonio averages 118.3 points per game (14th) and shoots 49.4 percent from the field (4th), including 36.1 percent from three (15th). The Spurs allow 112.3 points per game (4th) on 45.1 percent shooting (5th), including 39.2 percent from beyond the arc (28th). They are 11th in NET rating, including 8th in offensive rating and 13th in defensive rating, per Dunks and Threes.

San Antonio Spurs Injury Report:

  • Victor Wembanyama and Stephon Castle remain out.

Denver leads the NBA in offensive efficiency rating

Denver (13-4 SU, 11-6 ATS, and 10-7 O/U) beat Memphis 125-115 on Monday. The Nuggets are 8-2 SU and 7-3 ATS in their last ten games, and the over was 6-4.

C Nikola Jokic leads Denver in scoring at 29.6 points per game on 62.6 percent shooting. He also averages 12.8 rebounds and 11.1 assists. A few other Nuggets to watch on Friday against the Spurs are G Jamal Murray (23.3 PPG and 6.8 APG), G Christian Braun (11.4 PPG and 4.0 RPG), and G Tim Hardaway Jr. (11.1 PPG).

Denver scores 123.8 points per game (2nd) and shoots 50.6 percent from the field (2nd), including 37.8 percent from beyond the arc (6th). The Nuggets give up 113.8 points per game (8th) on 45.5 percent shooting (8th), including 32.0 percent from downtown (3rd). They are 3rd in NET rating, including 1st in offensive rating and 12th in defensive rating, per Dunks and Threes.

Denver Nuggets Injury Report:

  • Aaron Gordon and Christian Braun remain sidelined.
  • G Julian Strawther is day-to-day (back).

Spurs vs. Nuggets Pick and Preview

Spread Pick for Spurs vs. Nuggets

  • San Antonio +10.5 (4 Units)

It's tough to count out the Spurs. They win or at least keep the score close when they shouldn't, at least on paper. San Antonio is simply one of the best-run pro sports organizations. After winning and covering in four of their previous five, the visitors will cover Friday's spread. They won straight-up as one-point 'dogs on Wednesday, as Fox erupted for 37 and Vassell added a cool 23 on 9-for-17 shooting. With or without Wemby, these guys are going to play like they're supposed to win.

Denver has also been playing well, but it has struggled to cover three similarly large spreads recently, losing as 12.5-point, 10.5-point, and 11-point favorites in three of its previous five games. Back San Antonio on Friday ATS!

Over/Under Pick for Spurs vs. Nuggets

  • Under 236.5 (5 Units)

The Spurs and Nuggets are slow-tempo squads, ranking 23rd and 25th in pace this season. While both teams also rank in the top ten in offensive efficiency rating, this total is too high. The under has cashed in five of the Spurs' last six games, as they've held five of those opponents to 111 or fewer points. They certainly miss Wemby's rim defense, but his absence hasn't allowed teams to pile on the points by attacking them in the paint. I'm also confident that the Nuggets will bring their A-game defensively, holding the visitors in check from three-point range. While they're less stout inside the arc (17th in 2PT defense), San Antonio shot just 44.1 percent from two-point range last game and is down a few percentage points since Wemby's injury.

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