Trail Blazers vs Cavaliers, Picks, Odds, Preview, and Prediction, Wednesday, December 3, 2025

By: Liam Keating Published 12/03/2025, 10:48 AM ET
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It’s an East vs West matchup on Wednesday, Dec. 3. Read our Portland Trail Blazers vs Cleveland Cavaliers prediction along with along with other NBA Picks. The Trail Blazers are 8-13 and they are struggling, losing 10 of their last 13 games. This is a back-to-back for Portland as they lost to Toronto on Tuesday night. The Cavaliers are 13-9 and they have won four of their last six games at home. Cleveland are currently sitting in sixth place in the East. These two teams will meet with tip-off set for 7 P.M. EST.

Portland comes close to knocking off Toronto

Portland is 8-13 overall this season. The Trail Blazers are sitting in 10th place at the moment as they are 12 games back of first place. They are also five games out of the No. 6 seed. Portland is 5-7 when they have played on the road this year. The Trail Blazers have lost three straight games. They have also lost 10 of their last 13 games.

In their last game, the Trail Blazers lost 121-118 to the Raptors away from home on Tuesday, Dec. 2. Portland held a slight lead in the first quarter, but they were never able to find a lead for the rest of the game. They tried to mount a comeback, outscoring Toronto 36-24 in the fourth quarter, but it wasn’t enough. Portland shot 49% from the field and 38% from behind the 3-point line. Deni Avdija led the team with 25 points on 6-for-15 shooting on the year.

Avdija leads the team with 25.8 points per game. Donovan Clingan is grabbing a team-high 10 rebounds, while Jrue Holiday is passing for a team-high 8.2 assists per game.

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Portland ranks 23rd in offensive efficiency this season. They are also the 23rd-ranked defensively efficient team, while the Trail Blazers also rank 11th in rebounding.

Portland is averaging 118.3 points per game, which ranks 14th. They are the fourth-worst shooting team, making 44.3% from the field. The Trail Blazers are hitting 32.3% from behind the 3-point line, which places them second-worst.

On defense, Portland is allowing 121.2 points per game, which ranks 25th. They are allowing 48.2% from the field, which places them 23rd. The Trail Blazers are the 19th-ranked 3-point defensive team, allowing 36.6% from behind the arc.

Portland is 11-10 against the spread this season. They are 4-7 against the spread as an away team. The Trail Blazers are 3-0 against the spread when they have no rest. Portland is 9-3 against the spread as an underdog. The over is 13-7 when Portland has played this season. The under is 2-1 when Portland has played on the heels of a back-to-back. The under is 3-1 when they have played Eastern Conference foes.

Key injuries 

  • Matisse Thybulle (thumb), questionable 
  • Donovan Clingan (illness), questionable 
  • Scoot Henderson (hamstring), out 
  • Jrue Holiday (calf), out 

Cleveland winners of 4 of last 6 home games

Cleveland is 13-9 overall this season. The Cavaliers are in sixth place in the Eastern Conference this season. They are 4.5 games back of the Pistons for first place. Cleveland is 8-4 when they have played at home. They have lost three of their last four games coming into this matchup. Cleveland has won four of their last six games at home.

In their last game, the Cavaliers defeated Indiana 135-119 on the road on Monday, Dec. 1. It was a convincing win for Cleveland after they secured the lead in the first few minutes. The Cavaliers never relinquished the lead after the opening minutes of the game. Cleveland shot 51% from the field and 35% from behind the 3-point line. Cleveland out-rebounded Indiana 48-36 in the win, while they also forced 14 turnovers. Donovan Mitchell poured in a game-high 43 points on 16-for-27 points.

Mitchell leads the team with 30.6 points and 5.5 assists per game. Evan Mobley is grabbing a team-high 9 rebounds per game, too.

Cleveland ranks 11th in offensive efficiency and 12th in defensive efficiency. The Cavaliers are the 17th-ranked team in rebounding.

Cleveland is averaging 119.6 points per game, which ranks seventh in the league. They are the 19th-ranked shooting team, making 46.3% from the field. The Cavaliers are hitting 35.3% from behind the 3-point line, placing them 19th.

On defense, Cleveland is allowing 115.8 points per game, which ranks 12th. They are the 14th-ranked defense, allowing 46.7% from the field. Opponents are making 36.3% from behind the 3-point line, which ranks Cleveland 16th.

Cleveland is 7-15 against the spread this season. The Cavaliers are 3-9 against the spread when playing at home. They are 4-8 against the spread after a win. They are also 1-2 against the spread vs the West. The under is 12-10 when the Cavaliers have played this year. The under is 7-5 after a Cleveland win. The under is 3-0 against the West. The under is also 9-3 when the Cavaliers have played at home.

Key injuries 

  • Lonzo Ball (illness), probable
  • Sam Merrill (hand), out
  • Max Strus (foot), out
  • Jarrett Allen (finger), out
  • Larry Nance Jr. (calf), out

Portland Trail Blazers vs Cleveland Cavaliers Picks

Trail Blazers vs Cavaliers Spread Pick

  • Portland Trail Blazers +10 (5 Units)

Cleveland has had a hard time of blowing teams out this year, especially against teams that they should beat. The Cavaliers are 3-9 against the spread at home and 4-8 against the spread after a win. Cleveland’s lacking consistency on the offensive end, which is fueled by injuries across the board. Different lineups are consistently disrupting any flow that the team has this year. Portland hasn't been great, but they’ve done a really good job of keeping games close. The Trail Blazers are 3-0 against the spread when they have no rest. They are also 9-3 against the spread as an underdog. Deni Avdija is becoming an All-Star caliber player and should lead this team to a strong game against the Cavaliers.

Take Portland to cover. 

Trail Blazers vs Cavaliers Over/Under Pick

  • Under 238.5 (5 units)

Cleveland and Portland are two of the fastest teams in the NBA. The Trail Blazers rank third in pace, while the Cavaliers are the seventh fastest team. This is why the total is so high for this game, but it won’t be reached. Cleveland’s defense is underrated, ranking 12th in defensive efficiency. The Trail Blazers also rank 23rd in offensive efficiency. This will make for a low-scoring game as the under is 9-3 when Cleveland has played at home. The under is 2-1 when Portland has played on the heels of a back-to-back.

Take the under on Wednesday.  

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