New York Yankees vs Boston Red Sox, Picks and Prediction, Saturday, September 13, 2025

By: Liam Keating Published 09/13/2025, 03:31 AM ET
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It’s one of the best rivalries in baseball and it all goes down on Saturday, Sept. 13. Read our New York Yankees vs Boston Red Sox prediction along with our other MLB picks for the day. The Yankees and Red Sox are both in a wild-card spot as they both look to clinch a playoff berth in the coming weeks. The Red Sox have dominated the Yankees during the regular season. The Yankees are set to start Max Fried while Brayan Bello gets the nod for Boston. These two teams will meet with the first pitch set for 4:10 P.M. EST.

Yankees leading American League Wild Card race

New York is in second place in the American League East division. They are at least three games back of Toronto for the divisional lead. The Yankees are leading the AL wild card race as they have a 4.5 game lead over the field for a playoff spot. The Yankees are above .500 when playing on the road this year. Entering Friday night, the Yankees are 2-8 this year against the Red Sox. They are coming off of a series where they lost two of three games against Detroit.

Max Fried gets the start for the Yankees in this matchup. The left-handed pitcher is 16-5 with a 3.02 ERA in 29 starts this season. His last start saw him throw seven innings against Toronto on Sept. 7. He allowed three runs and six hits in a 4-3 win. New York is 19-10 when Fried has started this season. They are also 9-6 when he has started on the road. They are 0-2 when he has started against Boston, though. He’s thrown 13 innings and he’s allowed two runs and 10 hits against the Red Sox, while the Yankees' offense hasn’t scored a run in those two innings.

The Yankees are hitting .249 this season, which ranks 14th in the league. They have scored the most runs, while they rank 14th in hits. New York has hit the most home runs while they have struck out the fourth most times. They are hitting .257 during road games, but they have a .236 batting average in the second half of the season. They have a .235 batting average in September and a .218 batting average in 10 games versus Boston.

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Red Sox pushing for wild card spot

Boston is in third place in the American League East division. They are at least 3.5 games back of the Blue Jays for the divisional lead and they are one game out of the Yankees for second place. The Red Sox are in second place in the American League wild-card race. They do have a four-game lead over the field as they are looking strong to make the playoffs. Boston has been dominant at home with their 44-28 record coming into this series. Entering Friday’s game, the Red Sox have won three of their last four games.

On Saturday, Brayan Bello will start for the Red Sox against the Yankees. He is 11-6 with a 3.12 ERA in 25 starts and one relief appearance. His last start saw him throw six innings against the Diamondbacks on Sept. 7. He allowed three runs and four hits in a 7-4 win. The Red Sox are 16-10 when Bello has pitched this year. He has pitched twice against the Yankees this year, with both outings ending in wins. He’s thrown a total of 14 innings and he’s allowed six hits and zero runs during that stretch.

The Red Sox are hitting .254 this season, which ranks fifth-best in the league. They have scored the fifth most runs and they rank fifth in this. Boston has hit the 12th most home runs, but they have struck out the seventh most times. They are hitting .264 at home this season and .251 since the All-Star break. They have a .287 batting average in nine games this month. The Red Sox are hitting .264 in 10 games versus the Yankees.

New York Yankees vs Boston Red Sox Pick

Spread Pick for New York Yankees vs Boston Red Sox

  • Boston Red Sox -1.5 (5 units) 

Boston has simply had the Yankees' number this year. Coming into the series, they are 8-2 versus their rivals in the Bronx. The pitching and offense have been great against them and with their home crowd pushing them towards a divisional lead, the Red Sox will have the momentum in this game. They are starting Brayan Bello, who has not wavered against the Yankees’ lineup. He’s pitched 14 innings against them and has allowed zero runs and six hits in two starts. The Yankees can’t hit him and their offense is reeling at the moment. They have. .218 batting average versus Boston this season and a .235 average in September. The Red Sox are hitting .264 versus New York and are in fine form, hitting .287 this month. The Yankees are starting Max Fried and they are 9-6 when he has started on the road, but he has lost both starts versus Boston. This will be a low scoring game with the Red Sox’s lineup getting the needed runs late in the game.

Take Boston to cover. 

Over/Under Pick for New York Yankees

  • Under 8.5 runs (5 units)

The two starting pitchers have been great against each other this season. Brayan Bello has allowed zero runs and just six hits in 14 innings versus the Yankees this year. New York’s Max Fried thrown 13 innings and he’s allowed two runs and 10 hits against Boston. Expect another pitcher’s duel in this rivalry matchup especially with the Yankees hitting .235 this month and .218 against Boston this season.

Take the under on Saturday. 

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